1,342 research outputs found

    Analysis of a Waveguide-Fed Metasurface Antenna

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    The metasurface concept has emerged as an advantageous reconfigurable antenna architecture for beam forming and wavefront shaping, with applications that include satellite and terrestrial communications, radar, imaging, and wireless power transfer. The metasurface antenna consists of an array of metamaterial elements distributed over an electrically large structure, each subwavelength in dimension and with subwavelength separation between elements. In the antenna configuration we consider here, the metasurface is excited by the fields from an attached waveguide. Each metamaterial element can be modeled as a polarizable dipole that couples the waveguide mode to radiation modes. Distinct from the phased array and electronically scanned antenna (ESA) architectures, a dynamic metasurface antenna does not require active phase shifters and amplifiers, but rather achieves reconfigurability by shifting the resonance frequency of each individual metamaterial element. Here we derive the basic properties of a one-dimensional waveguide-fed metasurface antenna in the approximation that the metamaterial elements do not perturb the waveguide mode and are non-interacting. We derive analytical approximations for the array factors of the 1D antenna, including the effective polarizabilities needed for amplitude-only, phase-only, and binary constraints. Using full-wave numerical simulations, we confirm the analysis, modeling waveguides with slots or complementary metamaterial elements patterned into one of the surfaces.Comment: Original manuscript as submitted to Physical Review Applied (2017). 14 pages, 14 figure

    A Role for the SmpB-SsrA System in Yersinia pseudotuberculosis Pathogenesis

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    Yersinia utilizes a sophisticated type III secretion system to enhance its chances of survival and to overcome the host immune system. SmpB (small protein B) and SsrA (small stable RNA A) are components of a unique bacterial translational control system that help maintain the bacterial translational machinery in a fully operational state. We have found that loss of the SmpB-SsrA function causes acute defects in the ability of Yersinia pseudotuberculosis to survive in hostile environments. Most significantly, we show that mutations in smpB-ssrA genes render the bacterium avirulent and unable to cause mortality in mice. Consistent with these observations, we show that the mutant strain is unable to proliferate in macrophages and exhibits delayed Yop-mediated host cell cytotoxicity. Correspondingly, we demonstrate that the smpB-ssrA mutant suffers severe deficiencies in expression and secretion of Yersinia virulence effector proteins, and that this defect is at the level of transcription. Of further interest is the finding that the SmpB-SsrA system might play a similar role in the related type III secretion system that governs flagella assembly and bacterial motility. These findings highlight the significance of the SmpB-SsrA system in bacterial pathogenesis, survival under adverse environmental conditions, and motility

    Mean platelet volume in brucellosis: correlation between brucella standard serum agglutination test results, platelet count, and C-reactive protein.

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    Background: Brucellosis, a zoonotic infection, was most widely diagnosed by the Brucella standard serum agglutination test (SAT). No previous publication has demonstrated a correlation between the degree of Brucella SAT agglutination positivity and the severity of brucellosis infection.Objective: To contribute to the clarification of the relationship between patelets and brucellosis. It is also aimed at evaluating the usefulness of the SAT titer as a measure of brucellosis severity.Material and Methods: We compared the control (n=60) and patients (n=96) groups in terms of mean platelet volume (MPV), C-reactive protein (CRP) and platelet values. Patients were grouped according to their degree of agglutination positivity titers and compared by means of CRP, MPV and platelet values. We also investigated the relationship among logarithmic values of MPV, platelet and CRP parameters for each group.Results: Although statistically meaningful difference was observed between control and patients group in terms of MPV and platelet value, there were no statistically significant differences observed among patients groups. The physiological negative correlation between MPV and platelet count was not encountered in group 2 and 3. Logarithmic values of CRP were not correlated with logarithmic values of MPV and platelet counts.Conclusion: The MPV could be a new parameter to evaluate hematologic abnormalities in patients with brucellosis. The SAT titer was not a useful measure for evaluation of the severity of brucellosis.Keywords: Brucella, CRP, platelet count, mean platelet volume, agglutinatio

    Raman Enhancement on a Broadband Meta-Surface

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    Cataloged from PDF version of article.Plasmonic metamaterials allow confinement of light to deep subwavelength dimensions, while allowing for the tailoring of dispersion and electromagnetic mode density to enhance specific photonic properties. Optical resonances of plasmonic molecules have been extensively investigated; however, benefits of strong coupling of dimers have been overlooked. Here, we construct a plasmonic meta-surface through coupling of diatomic plasmonic molecules which contain a heavy and light meta-atom. Presence and coupling of two distinct types of localized modes in the plasmonic molecule allow formation and engineering of a rich band structure in a seemingly simple and common geometry, resulting in a broadband and quasi-omni-directional meta-surface. Surface-enhanced Raman scattering benefits from the simultaneous presence of plasmonic resonances at the excitation and scattering frequencies, and by proper design of the band structure to satisfy this condition, highly repeatable and spatially uniform Raman enhancement is demonstrated. On the basis of calculations of the field enhancement distribution within a unit cell, spatial uniformity of the enhancement at the nanoscale is discussed. Raman scattering constitutes an example of nonlinear optical processes, where the wavelength conversion during scattering may be viewed as a photonic transition between the bands of the meta-material

    Grating coupler integrated photodiodes for plasmon resonance based sensing

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    Cataloged from PDF version of article.In this work, we demonstrate an integrated sensor combining a grating-coupled plasmon resonance surface with a planar photodiode. Plasmon enhanced transmission is employed as a sensitive refractive index (RI) sensing mechanism. Enhanced transmission of light is monitored via the integrated photodiode by tuning the angle of incidence of a collimated beam near the sharp plasmon resonance condition. Slight changes of the effective refractive index (RI) shift the resonance angle, resulting in a change in the photocurrent. Owing to the planar sensing mechanism, the design permits a high areal density of sensing spots. In the design, absence of holes that facilitate resonant transmission of light, allows an easy-to-implement fabrication procedure and relative insensitivity to fabrication errors. Theoretical and experimental results agree well. An equivalent long-term RI noise of 6.3 x 10(-6) RIU/root Hz is obtained by using an 8 mW He-Ne laser, compared to a shot-noise limited theoretical sensitivity of 5.61 x 10(-9) RIU/root Hz. The device features full benefits of grating-coupled plasmon resonance, such as enhancement of sensitivity for non-zero azimuthal angle of incidence. Further sensitivity enhancement using balanced detection and optimal plasmon coupling conditions are discussed

    Electrochemically tunable ultrafast optical response of graphene oxide

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    Cataloged from PDF version of article.We demonstrate reversible and irreversible changes in the ultrafast optical response of multilayer graphene oxide thin films upon electrical and optical stimulus. The reversible effects are due to electrochemical modification of graphene oxide, which allows tuning of the optical response by externally applied bias. Increasing the degree of reduction in graphene oxide causes excited state absorption to gradually switch to saturable absorption for shorter probe wavelengths. Spectral and temporal properties as well as the sign of the ultrafast response can be tuned either by changing the applied bias or exposing to high intensity femtosecond pulses. © 2011 American Institute of Physics

    A real-time, scalable, fast and highly resource efficient decoder for a quantum computer

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    Quantum computers promise to solve computing problems that are currently intractable using traditional approaches. This can only be achieved if the noise inevitably present in quantum computers can be efficiently managed at scale. A key component in this process is a classical decoder, which diagnoses the errors occurring in the system. If the decoder does not operate fast enough, an exponential slowdown in the logical clock rate of the quantum computer occurs. Additionally, the decoder must be resource efficient to enable scaling to larger systems and potentially operate in cryogenic environments. Here we introduce the Collision Clustering decoder, which overcomes both challenges. We implement our decoder on both an FPGA and ASIC, the latter ultimately being necessary for any cost-effective scalable solution. We simulate a logical memory experiment on large instances of the leading quantum error correction scheme, the surface code, assuming a circuit-level noise model. The FPGA decoding frequency is above a megahertz, a stringent requirement on decoders needed for e.g. superconducting quantum computers. To decode an 881 qubit surface code it uses only 4.5%4.5\% of the available logical computation elements. The ASIC decoding frequency is also above a megahertz on a 1057 qubit surface code, and occupies 0.06 mm2^2 area and consumes 8 mW of power. Our decoder is optimised to be both highly performant and resource efficient, while its implementation on hardware constitutes a viable path to practically realising fault-tolerant quantum computers.Comment: 11 pages, 4 figure

    Systematic Review of Health Literacy and Health Promotion in School-Aged Adolescents

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    Background: The literature has identified gaps in adolescent health literacy (AHL) measurements, as well as how the health literacy (HL) level is related to health promotion (HP) aspects. This study aimed to examine the tools used to measure HL and determine its relation with HP among adolescents. Methods: Three online databases (HINARI, PubMed, and DOAJ) were searched to conduct a systematic assessment of papers published between January 1, 2016, and January 1, 2021. In this review, 373 articles were identified from these databases. After removing duplicates and screening titles and abstracts of articles, 49 full texts were selected for full-text reading. After comprehensive reading, 23 papers were appraised for qualitative synthesis. Results: Of the 23 reviewed papers, 21 focused on assessing AHL measures, and 15 addressed the association between AHL and HP. Seven studies used the HL School-Aged Children instrument. The findings suggested that the methodological and conceptual underpinnings of HL measures are insufficient. Furthermore, HL acts as an independent and positive mediator for many facets of HP. Conclusion: This review offers a warning to practitioners and educationists interested in measuring HL as the number of measurement tools is quite huge with different tools applying different scales
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