1,504 research outputs found

    The estimation of airplane performance from wind tunnel tests on conventional airplane models

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    Calculations of the magnitude of the correction factors and the range of their variations for wind tunnel models used in making aircraft performance predictions were made for 23 wind tunnel models. Calculated performances were compared with those actually determined for such airplanes as have been built and put through flight test. Except as otherwise noted, all the models have interplane struts and diagonal struts formed to streamwise shape. Wires were omitted in all cases. All the models were about 18 inches in span and were tested in a 4-foot wind tunnel. Results are given in tabular form

    Binary separation in very thin nematic films: thickness and phase coexistence

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    The behavior as a function of temperature of very thin films (10 to 200 nm) of pentylcyanobiphenyl (5CB) on silicon substrates is reported. In the vicinity of the nematic/isotropic transition we observe a coexistence of two regions of different thicknesses: thick regions are in the nematic state while thin ones are in the isotropic state. Moreover, the transition temperature is shifted downward following a 1/h^2 law (h is the film thickness). Microscope observations and small angle X-ray scattering allowed us to draw a phase diagram which is explained in terms of a binary first order phase transition where thickness plays the role of an order parameter.Comment: 5 pages, 3 figures, submitted to PRL on the 26th of Apri

    Towards a Linked democracy model

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    In this chapter we lay out the properties of participatory ecosystems as linked democracy ecosystems. The goal is to provide a conceptual roadmap that helps us to ground the theoretical foundations for a meso-level, institutional theory of democracy. The identification of the basic properties of a linked democracy eco-system draws from different empirical examples that, to some extent, exhibit some of these properties. We then correlate these properties with Ostrom's design principles for the management of common-pool resources (as generalised to groups cooperating and coordinating to achieve shared goals) to open up the question of how linked democracy ecosystems can be governed

    The Chicken Yolk Sac IgY Receptor, a Mammalian Mannose Receptor Family Member, Transcytoses IgY across Polarized Epithelial Cells

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    In mammals the transfer of passive immunity from mother to young is mediated by the MHC-related receptor FcRn, which transports maternal IgG across epithelial cell barriers. In birds, maternal IgY in egg yolk is transferred across the yolk sac to passively immunize chicks during gestation and early independent life. The chicken yolk sac IgY receptor (FcRY) is the ortholog of the mammalian phospholipase A2 receptor, a mannose receptor family member, rather than an FcRn or MHC homolog. FcRn and FcRY both exhibit ligand binding at the acidic pH of endosomes and ligand release at the slightly basic pH of blood. Here we show that FcRY expressed in polarized mammalian epithelial cells functioned in endocytosis, bidirectional transcytosis, and recycling of chicken FcY/IgY. Confocal immunofluorescence studies demonstrated that IgY binding and endocytosis occurred at acidic but not basic pH, mimicking pH-dependent uptake of IgG by FcRn. Colocalization studies showed FcRY-mediated internalization via clathrin-coated pits and transport involving early and recycling endosomes. Disruption of microtubules partially inhibited apical-to-basolateral and basolateral-to-apical transcytosis, but not recycling, suggesting the use of different trafficking machinery. Our results represent the first cell biological evidence of functional equivalence between FcRY and FcRn and provide an intriguing example of how evolution can give rise to systems in which similar biological requirements in different species are satisfied utilizing distinct protein folds
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