Hot Exoplanet Atmospheres Resolved with Transit Spectroscopy (HEARTS) VIII. Nondetection of sodium in the atmosphere of the aligned planet KELT-10b

We searched for potential atmospheric species in KELT-10b, focusing on sodium doublet lines (Na i; 589 nm) and the Balmer alpha line (H $\alpha$; 656 nm) in the transmission spectrum. Furthermore, we measured the planet-orbital alignment with the spin of its host star. We used the Rossiter-McLaughlin Revolutions technique to analyze the local stellar lines occulted by the planet during its transit. We used the standard transmission spectroscopy method to probe the planetary atmosphere, including the correction for telluric lines and the Rossiter-McLaughlin effect on the spectra. We analyzed two new light curves jointly with the public photometry observations. We do not detect signals in the Na i and H $\alpha$ lines within the uncertainty of our measurements. We derive the 3-sigma upper limit of excess absorption due to the planetary atmosphere corresponding to equivalent height Rp to 1.8Rp (Na i) and 1.9Rp (H $\alpha$). The analysis of the Rossiter-McLaughlin effect yields the sky-projected spin-orbit angle of the system $\lambda$ = -5.2 $\pm$ 3.4 and the stellar projected equatorial velocity $v_{eq} \sin{i_\star}$ = 2.58 $\pm$ 0.12 km/s. Photometry results are compatible within 1 -sigma with previous studies. We found no evidence of Na i and H $\alpha$, within the precision of our data, in the atmosphere of KELT-10b. Our detection limits allow us to rule out the presence of neutral sodium or excited hydrogen in an escaping extended atmosphere around KELT-10b. We cannot confirm the previous detection of Na i at lower altitudes with VLT/UVES. We note, however, that the Rossiter-McLaughlin effect impacts the transmission spectrum on a smaller scale than the previous detection with UVES. Analysis of the planet-occulted stellar lines shows the sky-projected alignment of the system, which is likely truly aligned due to tidal interactions of the planet with its cool (Teff < 6250 K) host star.Comment: Accepted in A&

Regularization Independent Analysis of the Origin of Two Loop Contributions to N=1 Super Yang-Mills Beta Function

We present a both ultraviolet and infrared regularization independent analysis in a symmetry preserving framework for the N=1 Super Yang-Mills beta function to two loop order. We show explicitly that off-shell infrared divergences as well as the overall two loop ultraviolet divergence cancel out whilst the beta function receives contributions of infrared modes.Comment: 7 pages, 2 figures, typos correcte

On the equivalence between Implicit Regularization and Constrained Differential Renormalization

Constrained Differential Renormalization (CDR) and the constrained version of Implicit Regularization (IR) are two regularization independent techniques that do not rely on dimensional continuation of the space-time. These two methods which have rather distinct basis have been successfully applied to several calculations which show that they can be trusted as practical, symmetry invariant frameworks (gauge and supersymmetry included) in perturbative computations even beyond one-loop order. In this paper, we show the equivalence between these two methods at one-loop order. We show that the configuration space rules of CDR can be mapped into the momentum space procedures of Implicit Regularization, the major principle behind this equivalence being the extension of the properties of regular distributions to the regularized ones.Comment: 16 page

Mitochondrial Haplogroup H1 in North Africa: An Early Holocene Arrival from Iberia

The Tuareg of the Fezzan region (Libya) are characterized by an extremely high frequency (61%) of haplogroup H1, a mitochondrial DNA (mtDNA) haplogroup that is common in all Western European populations. To define how and when H1 spread from Europe to North Africa up to the Central Sahara, in Fezzan, we investigated the complete mitochondrial genomes of eleven Libyan Tuareg belonging to H1. Coalescence time estimates suggest an arrival of the European H1 mtDNAs at about 8,000–9,000 years ago, while phylogenetic analyses reveal three novel H1 branches, termed H1v, H1w and H1x, which appear to be specific for North African populations, but whose frequencies can be extremely different even in relatively close Tuareg villages. Overall, these findings support the scenario of an arrival of haplogroup H1 in North Africa from Iberia at the beginning of the Holocene, as a consequence of the improvement in climate conditions after the Younger Dryas cold snap, followed by in situ formation of local H1 sub-haplogroups. This process of autochthonous differentiation continues in the Libyan Tuareg who, probably due to isolation and recent founder events, are characterized by village-specific maternal mtDNA lineages

Uniparental Genetic Heritage of Belarusians: Encounter of Rare Middle Eastern Matrilineages with a Central European Mitochondrial DNA Pool

Ethnic Belarusians make up more than 80% of the nine and half million people inhabiting the Republic of Belarus. Belarusians together with Ukrainians and Russians represent the East Slavic linguistic group, largest both in numbers and territory, inhabiting East Europe alongside Baltic-, Finno-Permic- and Turkic-speaking people. Till date, only a limited number of low resolution genetic studies have been performed on this population. Therefore, with the phylogeographic analysis of 565 Y-chromosomes and 267 mitochondrial DNAs from six well covered geographic sub-regions of Belarus we strove to complement the existing genetic profile of eastern Europeans. Our results reveal that around 80% of the paternal Belarusian gene pool is composed of R1a, I2a and N1c Y-chromosome haplogroups – a profile which is very similar to the two other eastern European populations – Ukrainians and Russians. The maternal Belarusian gene pool encompasses a full range of West Eurasian haplogroups and agrees well with the genetic structure of central-east European populations. Our data attest that latitudinal gradients characterize the variation of the uniparentally transmitted gene pools of modern Belarusians. In particular, the Y-chromosome reflects movements of people in central-east Europe, starting probably as early as the beginning of the Holocene. Furthermore, the matrilineal legacy of Belarusians retains two rare mitochondrial DNA haplogroups, N1a3 and N3, whose phylogeographies were explored in detail after de novo sequencing of 20 and 13 complete mitogenomes, respectively, from all over Eurasia. Our phylogeographic analyses reveal that two mitochondrial DNA lineages, N3 and N1a3, both of Middle Eastern origin, might mark distinct events of matrilineal gene flow to Europe: during the mid-Holocene period and around the Pleistocene-Holocene transition, respectively

A checklist of native freshwater fish from Brantas River, East Java, Indonesia

Hasan V, Mamat NB, South J, Ottoni FP, Widodo MS, Arisandi P, Isroni W, Jerikho R, Samitra D, Faqih AR, Simanjuntak CPH, Mukti AT. 2022. A checklist of native freshwater fish from Brantas River, East Java, Indonesia. Biodiversitas 23: 6031-6039. This study aims to provide information on the freshwater fish species composition of the Brantas River, the second-largest river in Java, Indonesia. All samples used in this study were the caught activities during Fish Resource Survey (form May 5, 2021 to August 20, 2022). Sampling was carried out in four stations of the Brantas River, representing upstream, the Karangkates Reservoir, midstream, and downstream. This work recorded 42 fish species divided into 35 genera and 21 families. Cyprinidae was the dominant family, comprising 12 genera and 15 species. According to the IUCN Red List, most fish species inhabiting the Brantas River have a conservation status of Least Concern (LC) or Data Deficient (DD), except for Rasbora lateristriata which is categorized as Vulnerable (VU). Genera Tor and Neolissochilus are rarely found in Javanese waters. We suggest that the conservation status of these species should be reviewed. Information on habitat use and ecological interactions of fish occurring in the Brantas River are needed urgently to make appropriate conservation decisions and plans. Therefore, we suggest that more collections need to be carried out in the studied river, as well as studies based on eDNA analysis and research incorporating both morphological and molecular data

Guidance on Noncorticosteroid Systemic Immunomodulatory Therapy in Noninfectious Uveitis : Fundamentals Of Care for UveitiS (FOCUS) Initiative

Supplemental material available at www.aaojournal.org. Supported by AbbVie, Inc., and the Fundamentals of Care for Uveitis Initiative National Faculty. This manuscript was developed subsequent to an AbbVie-sponsored literature review of noninfectious, nonanterior uveitis. The meeting was conducted to understand the available literature regarding the management of patients with noninfectious, nonanterior uveitis. The program involved a total of 139 experts from 28 countries, who were selected for participation by AbbVie. However, AbbVie was not involved in the development of the manuscript. The authors maintained complete control over the content and this manuscript reflects the opinions of the authors. AbbVie selected the discussion participants and reviewed the final manuscript draft for scientific accuracy, but the authors determined the final content. All authors made substantial contributions to the article or critically revised it for important intellectual content and approved the final manuscript. AbbVie provided funding to invited participants, including honoraria for their attendance at the meetings. Travel to and from the meetings was reimbursed. No payments were made to the authors for the development of this manuscript. Dhinakaran Sambandan, PhD, and Shula Sarner, PhD, of Lucid Partners, Burleighfield House, Buckinghamshire, United Kingdom, provided medical writing and editorial support to the authors in the development of this manuscript; financial support for these services was provided by AbbVie. AbbVie reviewed the manuscript, but was not involved in the methodology, data collection and analysis, or completion of this manuscript.Peer reviewedPublisher PD

TOI-858 B b: A hot Jupiter on a polar orbit in a loose binary

We report the discovery of a hot Jupiter on a 3.28-day orbit around a 1.08 M$_{Sun}$ G0 star that is the secondary component in a loose binary system. Based on follow-up radial velocity observations of TOI-858 B with CORALIE on the Swiss 1.2 m telescope and CHIRON on the 1.5 m telescope at the Cerro Tololo Inter-American Observatory (CTIO), we measured the planet mass to be $1.10\pm 0.08$ M$_{J}$ . Two transits were further observed with CORALIE to determine the alignment of TOI-858 B b with respect to its host star. Analysis of the Rossiter-McLaughlin signal from the planet shows that the sky-projected obliquity is $\lambda = 99.3\pm 3.8$. Numerical simulations show that the neighbour star TOI-858 A is too distant to have trapped the planet in a Kozai-Lidov resonance, suggesting a different dynamical evolution or a primordial origin to explain this misalignment. The 1.15 Msun primary F9 star of the system (TYC 8501-01597-1, at $\rho$ ~11") was also observed with CORALIE in order to provide upper limits for the presence of a planetary companion orbiting that star.Comment: Accepted for publication in A&

Guidance on noncorticosteroid systemic immunomodulatory therapy in noninfectious uveitis: fundamentals of care for uveitis (focus) initiative

Topic: An international, expert-led consensus initiative to develop systematic, evidence-based recommendations for the treatment of noninfectious uveitis in the era of biologics. Clinical Relevance: The availability of biologic agents for the treatment of human eye disease has altered practice patterns for the management of noninfectious uveitis. Current guidelines are insufficient to assure optimal use of noncorticosteroid systemic immunomodulatory agents. Methods: An international expert steering committee comprising 9 uveitis specialists (including both ophthalmologists and rheumatologists) identified clinical questions and, together with 6 bibliographic fellows trained in uveitis, conducted a Preferred Reporting Items for Systematic Reviews and Meta-Analyses protocol systematic reviewof the literature (English language studies from January 1996 through June 2016; Medline [OVID], the Central Cochrane library, EMBASE,CINAHL,SCOPUS,BIOSIS, andWeb of Science). Publications included randomized controlled trials, prospective and retrospective studies with sufficient follow-up, case series with 15 cases or more, peer-reviewed articles, and hand-searched conference abstracts from key conferences. The proposed statements were circulated among 130 international uveitis experts for review.Atotal of 44 globally representativegroupmembersmet in late 2016 to refine these guidelines using a modified Delphi technique and assigned Oxford levels of evidence. Results: In total, 10 questions were addressed resulting in 21 evidence-based guidance statements covering the following topics: when to start noncorticosteroid immunomodulatory therapy, including both biologic and nonbiologic agents; what data to collect before treatment; when to modify or withdraw treatment; how to select agents based on individual efficacy and safety profiles; and evidence in specific uveitic conditions. Shared decision-making, communication among providers and safety monitoring also were addressed as part of the recommendations. Pharmacoeconomic considerations were not addressed. Conclusions: Consensus guidelines were developed based on published literature, expert opinion, and practical experience to bridge the gap between clinical needs and medical evidence to support the treatment of patients with noninfectious uveitis with noncorticosteroid immunomodulatory agents