162 research outputs found

    Modeling The Nigerian Stock Exchange Data Characterized with Heteroscedasticity Disturbances Using Bayesian Approach

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    The stock exchange plays a crucial role in influencing the development of a country’s economy and growth.. This paper examines the Nigerian Stock Exchange data in the presence of heteroscedasticity disturbances parameters of Nigerian Stock Exchange using a wide range of variables. The results indicate that Bayesian estimation is reliable since the parameter estimates are consistent. Finally, Bayesian estimation when heteroscedasticity structure is present performs better than the homoscedasticity counterpart. Keywords: Bayesian estimation, heteroscedasticity, homoscedasticity, prior, posterior distribution

    Doe productivity indices and sire effects of a heterogeneous rabbit population in South-western Nigeria

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    Doe productivity indices are important in evaluating rabbit population since it influences the efficiency and profitability of rabbit production for small-holders and commercial rabbit production. Rabbits for this study were obtained from heterogeneous populations reared in south-western Nigeria, and a total of fifty-six adult rabbits (6 months old) comprising of 49 does and 7 sires were randomly allocated into sire families. Reproductive data were taken from each breeding doe and recorded for each sire family. The reproductive data obtained include annual productivity indices for each doe and sire family at birth, weaning and at week 12 post-partum. The total number of kits delivered at each kindling were recorded as the litter size at birth , the numbers weaned/doe/year were derived by multiplying the average litter size at weaning by number of litters/doe/year. The numbers of fryers/doe/year were obtained by multiplying average number weaned/doe by number of litters/doe/year multiplied by post weaning survival. Annual fryer yield (kg)/doe/year were obtained by multiplying total number of fryers/doe/year with live market weight (kg). Kilogram meat/doe/year were derived from the product of annual fryer yield (kg)/doe/year and the dressing percentage (0.55). Descriptive and inferential statistics were computed using SAS® 2004. Results showed that, the long kindling interval (93 to 115 days ) between two consecutive litters affected overall numerical doe productivity with a range of 6 to 27, 3 to 21 and 3 to 18 kits per doe/year at kindling, weaning and 12th week of age respectively. Annual fryer yield/doe/year was 20.24 Kg and the projected Kg meat/doe/year was 11.13 Kg. Mortality was highest in the first two weeks of life and continued to occur throughout the period of the study though at varying degrees across sire families. There was significant sire effect (P<0.05) in litter size at weaning and kindling- interval in the sire families. It was concluded that, the major factors affecting doe productivity indices in this population were low litter size at birth, long kindling interval and pre-weaning mortality. Thus, future genetic improvement programmes targeted towards productivity for this rabbit population must consider selection for traits which include increased litter size at birth, short kindling interval and low pre-weaning mortality in the maternal lines while litter size at weaning and kindling interval must be considered for the paternal lines

    Equine Influenza Virus and Vaccines

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    Equine influenza virus (EIV) is a constantly evolving viral pathogen that is responsible for yearly outbreaks of respiratory disease in horses termed equine influenza (EI). There is currently no evidence of circulation of the original H7N7 strain of EIV worldwide; however, the EIV H3N8 strain, which was first isolated in the early 1960s, remains a major threat to most of the world’s horse populations. It can also infect dogs. The ability of EIV to constantly accumulate mutations in its antibody-binding sites enables it to evade host protective immunity, making it a successful viral pathogen. Clinical and virological protection against EIV is achieved by stimulation of strong cellular and humoral immunity in vaccinated horses. However, despite EI vaccine updates over the years, EIV remains relevant, because the protective effects of vaccines decay and permit subclinical infections that facilitate transmission into susceptible populations. In this review, we describe how the evolution of EIV drives repeated EI outbreaks even in horse populations with supposedly high vaccination coverage. Next, we discuss the approaches employed to develop efficacious EI vaccines for commercial use and the existing system for recommendations on updating vaccines based on available clinical and virological data to improve protective immunity in vaccinated horse populations. Understanding how EIV biology can be better harnessed to improve EI vaccines is central to controlling EI

    Orbital apex syndrome caused by aspergilloma in an immunocompromised patient with cutaneous lymphoma: A case report of a rare entity

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    A 57-year-old man with a history of chemotherapy because of cutaneous lymphoma presented with an orbital apex syndrome. The cranial computed tomography scan revealed a tumour in the orbital apex, extending intradurally. With a suspected diagnosis of a neoplastic lesion, the patient underwent orbital surgery with optic nerve decompression. Histology revealed an aspergilloma. No other foci were seen and treatment with antifungals was started. In immunocompromised patients with intracranial tumours, infection is always a major consideration in the differential diagnosis, even if the reason for immunosuppression (in this case chemotherapy) dates back several months. Misdiagnosing an orbital apex lesion as a cancer and treating patients primarily with corticosteroids can be life threatening. Removal or biopsy of such lesions is essential in further treatment since antifungals have to be administered as fast as possible

    Giardia Infection in Recently Acclimatized Kalahari Red Goats in Nigeria

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    Prevalence of Giardia duodenalis in recently acquired and acclimatized Kalahari Red goats in Nigeria was determined using a commercially produced enzyme-linked immunosorbent assay (ELISA) kit. Giardia duodenalis coproantigens were detected in 46.9% of the faecal samples collected from 98 Kalahari Red goats. The highest (58.1%) and lowest rates (38.2%) were recorded in pre-weaned goat kids up to three months of age and adults goats over one year of age respectively. Infection was higher in females (56.8%) and diarrhoeic goats (75.0%) than males (38.9%) and non-diarrhoeic goats (45.7%) respectively. No significant difference (p>0.05) was observed in the infection rates among age categories, sexes and stool consistencies of the goats. The results of this study showed a high prevalence of Giardia infection in the Kalahari Red goat herd which may imply that they are susceptible to giardiasis if managed under conditions that may facilitate transmission from infected indigenous animals.Key words: ELISA, Giardia, goat, Kalahari Red, Nigeria

    Healthcare facilities in Nigeria: redefining standards and developing performance benchmarks for the professionalisation of FM practices

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    Healthcare in Nigeria is delivered by three tiers of government: the federal, state, and local government. Public hospital buildings suffer as facilities management (FM) functions are often neglected with significant effect on the operation of public hospitals in Nigeria. Most government hospitals have no tools for measuring FM performance. The aim of the study is to propose a performance measurement framework by redefining standards and developing performance benchmarks to improve current practices and to professionalise FM. The research adopted mixed qualitative and quantitative approaches to explore key issues and barriers to FM practices with stakeholders responsible for the management of hospital assets. The findings provided pointers on how to develop performance measurement in FM. Adoption of the FM performance measurement framework will assist policy makers in public hospitals in Nigeria to drive key organisational changes in the way assets are managed to support healthcare delivery and the professionalisation of FM

    Effect of pre-processing conditions on oil point pressure of sheanut (Vitellaria paradoxa) kernel

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    Oil point pressure of sheanut kernel was determined under different pre-processing conditions of moisture content, heating temperature, heating time and particle size. Results show that the pressure decreased as moisture content increased from 4% to 6%, and thereafter, increased with further increase in moisture content. It equally decreased with increase in temperature and heating time. Highest oil point pressure value was 2.6389MPa for coarse kernel particles at 4% moisture content heated at 50oC for 5 min, and 1.5554MPa for fine particles at 10% moisture content heated at 50°C for 5 min. Lowest value for coarse and fine kernel particles was 0.929MPa and 0.6380MPa respectively and this was obtained at the conditions of 6% moisture content, 100oC and 15 min heating time. ANOVA showed that all the pre-processing variables and their interactions significantly affected the oil point pressure of at 1% level of significance. This was confirmed using Response Surface Methodology. Multiple regression analysis yielded equations that expressed oil point pressure as a function of kernel moisture content, heating temperature and heating time. The models yielded coefficients that enabled oil point pressure of the kernel to be predicted with high coefficient of determination

    Exercise-induced bronchospasm and its associated factors among secondary school students in an urban community

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    Introduction: Exercise-induced bronchospasm (EIB) is a transient narrowing of the airway that usually occurs shortly after exercise. It occurs commonly in people with asthma; however EIB has also been reported in individuals without clinical asthma. The study aimed to determine the prevalence and factors associated with EIB among secondary school students. Methods: It was a descriptive cross-sectional school- based study involving secondary school students aged between 10 and 17 years without previous history of asthma. Subjects undertook a six-minute running test, spirometry was done and the best of three FEV1 readings were obtained pre-exercise, at 5, 10, 15 and 30 minutes post exercise. The diagnosis of EIB was made when there was a decrease in FEV1 of ≥10% from baseline after exercise. Results: Of the 265participants studied, 34 (12.8%) had EIB at 5 minutes post exercise. EIB was significantly more in the 10–13 years age group (χ2 = 18.416, p = <0.001), there was no significant gender difference. The presence of allergic (vernal) conjunctivitis and rhinitis were both significantly associated with the development of EIB (χ2 = 13.574, p < 0.001 and 0.011 respectively). There was no significant association with previous history of wheeze and exposure to indoor air pollution such as cooking with biomass fuel and parental cigarette smoking. Conclusion: EIB exist among non-asthmatic school children, and it is more frequent in the early adolescent age-group. Students with allergic conjunctivitis and rhinitis are more likely to manifest exercise induced bronchospasm

    Prognostic Roles of C-Reactive Protein and Erythrocyte Sedimentation Rate As Acute Phase Reactants in Mentally Challenged Subjects

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    Background: A mental disorder is a psychiatric disease that presents as mild or severe disturbances in a person’s behavior, mood, or thought. Mental illnesses are very common because of excessive stress. Recent studies show that mental illnesses are on the rise generally because of increasing stress. In Nigeria, medical records suggest an upsurge in mental health cases since the onset of the country’s economic downturn and the consequent trauma following it. The erythrocyte sedimentation rate (ESR) is an indirect marker of serum acute-phase protein concentrations, whereas C-reactive protein (CRP) is a direct protein measurement and it is inherently more well-defined. This study thus evaluated the roles of ESR and CRP as sensitive markers of inflammation and correlated their levels with severity stratification and prognosis in schizophrenic patients. Materials and Methods: This is a case-control study, and it was carried out on 40 patients diagnosed with schizophrenia. Thirty (30) controls were matched for age and sex; 8 millimeters of venous blood was collected from each participant using ante-cubital veins. Samples collected were dispensed into appropriate bottles foranalysis of CRP and hematological parameters using standard laboratory procedures. Statistical analysis of the data was done appropriately and P-value of less than 0.05 was considered as significant. Results: At the end of the study, the mean granulocytes, ESR, and CRP were significantly higher in schizophrenia cases than in the controls, while the mean PCV, RBC, and hemoglobin were significantly lower in the subjects. CRP had a higher area than ESR under the ROC curve (AUROC). Conclusion: This study thus evaluated the role of ESR and CRP as sensitive markers of inflammation and acute phase reactants in schizophrenic patients. The findings showed that CRP was a better diagnostic or predictor treatment outcome of schizophrenia

    Effect of Manure Application on Herbage Yield, Nutritive Value and Performance of Wad Sheep Fed Panicum maximum

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    Effect of types of manure on herbage yield, nutritive value and performance of WAD Sheep fed native Panicum maximum was investigated. The experiment was laid out in a randomized complete block design with each plot replicated thrice. Poultry manure and sheep - goat manure were applied through broadcasting to an established Panicum maximum stand to supply 200kgN/ha and 0kgN/ha (control). Grass herbage harvested from experiment plot were fed as sole diets to West African dwarf sheep to determine feed intake (g/h/d), nutrient digestibility (%) and weight gain (g/h/d). Results showed that Panicum maximum fertilized with poultry manure produced (P<0.05) higher values for biomass yield, number of tillers, tiller height, leaf length and leaf width. The chemical composition of Panicum maximum fertilized with poultry manure produced (P<0.05) higher CP and GE compared to sheep-goat manure. Similar trend of result was observed on mineral composition of Panicum maximum fertilized with poultry manure produced (P<0.05) higher values for P, K, Ca, Mg, Fe, Zn and Cu compared to sheep-goat manure. The feed intake (g/h/d), nutrient digestibility (%) and weight gain of the animals fed Panicum maximum fertilized with poultry manure produced higher values compared to its counterpart. It was concluded based on data obtained from this study that poultry manure application will promote higher yield and nutritive value for the Panicum maximum. Animals fed with this as sole diet and as short feeding regime experienced high weight gain. Keywords: Poultry manure, sheep - goat manure, herbage yield, Panicum maximum, WAD Shee
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