Detection Statistics of Pulse Signals at Declinations from +42o+42^o to +52o+52^o at the Frequency 111 MHz

A search for pulse signals was carried out in a new sky area included in the monitoring program for the search for pulsars and transients. Processing of several months data recorded in six frequency channels with a total bandwidth of 2.5 MHz showed that, on average, 4 pulses per hour are observed in each of the 24 connected stationary beams. Of these pulses, 18.3% are similar to those of pulsars. They are visible in one or two neighboring beams and have a pronounced dispersion shift, that is, they are recorded first at a high and then at a low frequency, which indicates the possible passage of the signal through the interstellar medium. Almost 68% of such detected pulses belong to six known pulsars with dispersion measures from 9 to 141 $pc/cm^3$, and almost all of the remaining pulses are either noise of an unknown nature or artifacts of the proposed pulse separation technique. An additional study of the selected array of 3650 obvious pulsar pulses revealed 13 pulses belonging to four rotating radio transients (RRATs). Their dispersion measures are in the range of 17-51 $pc/cm^3$. A search for regular (periodic) RRAT emission was carried out using power spectra summed over 121 days. Periodic radiation was not detected, but for two RRATs, upper estimates of the periods were obtained from measurements of the time intervals between pulses. The upper estimates of the integrated flux density of the detected RRATs are in the range 2-4 mJy at the frequency 111 MHz.Comment: published in Astronomy Report, translated by Yandex translator with correction of scientific lexis, 6 pages, 3 figures, 2 table

Morphological characteristics of brain lesions in HIV infection.

Currently, diseases of the central nervous system are a common cause of death of patients with HIV infection. The article presents results of retrospective analysis of etiotropic structure of 186 lethal cases and typical pathological changes of brain tissue of patients aged 21 to 61 years who had confirmed diagnosis of HIV and died of diseases associated with CNS damage in the Municipal infectious hospital in the city ofDnepr(Ukraine) in the period from 2011 to 2016. The most common causes of death in patients with HIV infection and CNS infection were cerebral tuberculosis (75.0%) including co-infection (n = 35) and meningoencephalitis that developed as a result of yeast fungal (15.6%). In the study of neuropathological processes in the autopsy material of the brain tissue of patients with HIV, various multifocal and diffuse morphological changes have been identified that can be presented in this work in the form of 4 groups: 1) Multiple nonspecific changes associated with both direct action of HIV and co-factors : infection, inflammation, hypoxia, etc., 2) Viral-induced vasculitis with hemorrhages, 3) Subacute aseptic encephalitis, 4) HIV-associated opportunistic infections. General pathomorphological changes in brain tissue are revealed that can cause similarities of clinical manifestations, can complicate differential diagnosis of cerebral lesions of various etiologies, and lead to a divergence of pre and postmortal diagnoses

The heart left ventricle diastolic function during exercises of different power in athletes

Целью исследования явилось изучение динамики показателей диастолической функции сердца спортсменов во время физических нагрузок различной мощности по данным эхокардиографии. Обследованы 68 спортсменов в возрасте от 12 до 27 лет, которые занимались плаваньем и волейболом. Посредством эходопплеркардиогрфического исследования установлены особенности кардиогемодинамических сдвигов у спортсменов во время физических нагрузок различной мощности. В работе доказано, что физические нагрузки средней и субмаксимальной мощности приводят к пропорциональному увеличению показателей диастолической функции сердца: скорости раннего диастолического наполнения левого желудочка (Е) до 81,9±20,0 см/с и скорости раннего диастолического движения створок митрального клапана (е’) до 16,6±5,7 см/с, что сохраняет их соотношение на уровне 6,73±2,83 у.е. Ранними симптомами физического перенапряжения сердечно-сосудистой системы были признаки нарушения релаксации миокарда во время диастолы, симптомы которого проявлялись при выполнении нагрузок максимальной мощности и приводили к большему приросту Е в сравнении с е’, что выражалось в увеличении Е/е’ до 7,33±3,69 у.е. (р<0,05). Продолжение выполнения физической нагрузки приводило к снижению глобальной систолической функции левого желудочка сердца. Дополнительным ранним показателем физического перенапряжения можно считать длительность нисходящей части раннего диастолического потока, которая при надпороговых нагрузках сокращалась более чем на 50 мс. The aim of the research was to investigate diastolic left ventricle function in athletes performing exercises requiring varying power using echocardiography. We surveyed 68 athletes aged from 12 to 27 years who were involved in swimming and volleyball. Echocardiography was used to assess cardiohaemodynamic changes in athletes using a bicycle ergometer to exercise at varying intensities. Exercising at submaximal and average power produces a proportional increase in indices of diastolic function of the heart: maximum speed of early diastolic mitral inflow streams (E) to 81,9±20,0 сm/s and maximum speed of early diastolic and mitral annulus velocity (е’) to 16,6±5,7 сm/s. It led to constant ratio E/e’ 6,73±2,83 units. The early symptoms of physical strain on the cardiovascular system were signs of myocardial relaxation violation during diastole. Symptoms appeared during the maximum power load and led to a large increase in E compared to e‘, which was manifested in the Е/е’ increase to 7,33±3,69 units (р<0,05). Continued physical activity lowered the global systolic function of the left ventricle. Additional early indicator of physical strain is length of early diastolic inflow deceleration time, which at above-threshold load was reduced more than 50 ms

Cardiovascular system and musculoskeletal changes of the sportsmen with polymorphisms of col1a1 gene

Целью исследования явилось определение влияния полиморфизма гена COL1A1 на состояние сердечно-сосудистой системы и опорно-двигательного аппарата у спортсменов. Обследованы 85 спортсменов в возрасте от 9 до 32 лет (средний возраст составил 23,2±4,3), которые занимались игровыми и циклическими видами спорта. Изменения в опорно-двигательном аппарате у спортсменов определяли с помощью антропометрии и соматоскопии, для оценки кардиогемодинамических сдвигов применяли эходопплеркардиогрфическое обследование, полиморфизм гена COL1A1 определяли методом полимеразной цепной реакции. Результаты исследования полиморфизма rs1800012 гена COL1A1 показали значительную распространенность среди исследуемых спортсменов гетерозиготного варианта GT, который встречался с частотой 67,1%, при этом гомозиготный вариант гена – ТТ установлен в 3,5%. Фенотипически генотип ТТ полиморфизма rs1800012 гена COL1A1 проявлялся в долихостеномелии, гипермобильности суставов, увеличении частоты деформаций позвоночника и эластичности кожи, уменьшении толщины кожи и, как следствие, в увеличении общего показателя вовлечения соединительной ткани в диспластический процесс, что связано с нарушени ем качественного состава соединительнотканного каркаса. Функционально неблагоприятный генотип ТТ приводит к изменениям морфологии сердца и крупных сосудов и отклонениям в процессах релаксации миокарда.The purpose of the study of the study is an identification of the extension and impact of polymorphism of COL1A1 gene on cardiovascular system and musculoskeletal state of athletes. 85 people in the ages from 9 to 32 (the average age was 23.2±4.3 years) with polymorphisms rs 1800012 of COL1A1 gene were examined during this investigation. With the help of anthropometry and somatoscopy skeletal abnormalities were established. To cardiohemodynamic investigation was used echocardiography. Polymorphisms of COL1A1 gene analysis was done by polymerase chain reaction method. The study results of polymorphism of COL1A1gene rs 1800012 expansion pointed at the critical extension of heterozygous gene GT in the selected for analysis population however heterozygous gene TT is found only with frequency of 3.5%. Associated trait of genotype TT of polymorphisms of COL1A1gene rs 1800012 involves dolichostenomelia, joints’ hypermobility, frequency increase of back bone deflection and as a result rising CT exhaustion level in dysplastic process that is corresponded with abnormality of CT skeleton qualitative composition. Functionary unfavorable genotype TT leads to the changes in heart morphology, major vessels and myocardium relaxation process deflection

Detection of two new RRATs at 111 MHz

A search for pulse signals in a area with declinations of +52\degr <\delta <+55\degr was carried out on the LPA LPI radio telescope. When processing ten months of observations recorded in six frequency channels with a channel width of 415 kHz and a total bandwidth of 2.5 MHz, 22 thousand events were found with a pronounced dispersion delay of signals over frequency channels, i.e. having signs of pulsar pulses. It turned out that the found pulses belong to four known pulsars and two new rotating radio transients (RRATs). An additional pulse search conducted in 32-channel data with a channel width of 78 kHz revealed 8 pulses for the transient J0249+52 and 7 pulses for the transient J0744+55. Periodic radiation of transients was not detected. The analysis of observations shows that the found RRATs are most likely pulsars with nullings, where the proportion of nulling is greater than 99.9\%.Comment: published in Astronomy Reports, translated by Yandex translator with correction of scientific lexis, 5 pages, 2 figures, 1 tabl

Core acid treatment influence on well reservoir properties in Kazan oil-gas condensate field

The research involves investigation of the influence of hydrochloric acid (HCI-12%) and mud acid ( mixture: HCl - 10 % and HF - 3 %) treatment on the Upper-Jurassic reservoir properties in Kazan oil-gas condensate field wells. The sample collection included three lots of core cylinders from one and the same depth (all in all 42). Two lots of core cylinders were distributed as following: first lot - reservoir properties were determined, and, then thin sections were cut off from cylinder faces; second lot- core cylinders were exposed to hydrochloric acid treatment, then, after flushing the reservoir properties were determined, and thin sections were prepared. Based on the quantitative petrographic rock analysis, involvin 42 thin sections, the following factors were determined: granulometric mineral composition, cement content, intergranular contacts and pore space structure. According to the comparative analysis of initial samples, the following was determined: content decrease of feldspar, clay and mica fragments, mica, clay and carbonate cement; increase of pore spaces while in the investigated samples- on exposure of rocks to acids effective porosity and permeability value range is ambiguous

GEMINGA: NEW OBSERVATIONS AT LOW RADIO FREQUENCIES

ABSTRACT. After nearly 10 years, we have succeeded to detect radio emission from Geminga more again. In this report we present new evidence for presence of radio emission from Geminga in the range 42-112 MHz. The observations were carried out on two sensitive transit radio telescopes We used three new digital receivers to detect the pulses and to obtain dynamic spectra.The examples of mean pulse profiles are presented. Exact value of the dispersion measure have been calculated using the simultaneous observations at three frequencies

Luminescent coordination polymers based on Ca²⁺ and octahedral cluster anions [{M₆Clⁱ₈}Clᵃ₆}²⁻ (M = Mo, W) : synthesis and thermal stability studies

Luminescent coordination polymers (CPs) based of inexpensive stable precursors are attractive materials for applications. Here we report the synthesis and evaluation of the stability and photophysical characteristics of the first examples of phosphorescent CPs based on octahedral molybdenum and tungsten cluster anions. Specifically 1D CP trans-[{Ca(OPPh₃)₄}{{M₆Clⁱ₈}Clᵃ₆}]∞ (M = Mo, W) can be obtained either directly at increased temperature or via intermediate phases [cis-Ca(OPPh₃)₄(H₂O)₂][{M₆Clⁱ₈}Clᵃ₆]∙2CH₃CN that are stable at room-temperature, but convert to the titled CP at temperatures above 100 °C

Method for assessing the information content of factors forming the cognitive independence of students

The article describes the problem of awakening the cognitive activity of students, arising due to revolutionary transformations in teaching technologies. It shows the need to study the factors that affect cognitive activity and assesses the information content of those factors. Based on the method of pair comparisons, a technology for ranking the factors affecting cognitive activity has been developed. A mathematical model of the formation and processing of expert assessment results and an example of calculations are given, and the feasibility of including the subsystem for evaluating factors affecting cognitive activity in the computer control system of the university is shown. The structure of an adaptive e-learning system based on the technology of taking into account the factors that form the cognitive independence of students is described Experiments carried out in 3 universities of Ukraine have shown that the use of the developed mathematical model and information technology allows to increase significantly academic performance and to decrease the frequency of refusals from independent work of students using the e-learning environment

Application of Basophil Activation Test with Anthraxin for Laboratory ( <I>in vitro</I>) Diagnostics of Anthrax

Demonstrated is the possibility to use in vitro basophil activation test with anthraxin, with registration of the results by means of flow cytometry, for anthrax diagnostics. This approach seems promising as it provides quantitative assessment of sensitization of the organism and does not cause its additional allergization. The duration of the analysis is 1h. The test is suggested for application, as an express one, for early and retrospective laboratory diagnostics of anthrax, estimation of post-vaccinal immunity