Specifics of defense and coping behavior among teachers experiencing a professional identity crisis

The issues addressed in the article are of particular relevance due to the necessity to provide research background for creating the system of psychological and pedagogical support for the professional development of teachers in the conditions of permanent changes in the system of education. The aim of the article is to describe specific interrelations between the reflection and the parameters of the teacher's axiological sphere (in particular, life-purpose orientations). The following research methods were used: theoretical analysis of psycholog-ical and educational literature, phenomenological method, questionnaires, and methods of mathematical and statistical data processing (descriptive statistics, comparative analysis (the Mann-Whitney U test). The results of the theoretical and empirical research provide ade-quate grounds for the conclusion that there is a definite interrelation between the parameters of reflection and the parameters of life-purpose orientations. It is proved that in the conditions of a professional identity crisis the teachers experience a significant reduction in the levels of life-purpose orientations, which in turn leads to intensification of reflection processes. At the same time, the obtained results suggest that the teachers can successfully overcome their professional crisis in case of formation of the cognitive component of the biographical reflection, aimed at the analysis of actions and means of understanding and organizing their life events. Implications of the research results. The research results expand our understanding of the essence and emotional experience of the professional identity crisis. They can be used in the designing the process of psychological support for the activities and professional development of teachers. © 2018 Authors

Уровень продукции IL-12β мононуклеарными лейкоцитами периферической крови в зависимости от клинической формы туберкулеза легких

The aim of this study was to evaluate the level of secretion of IL-12β by mononuclear leukocytes of peripheral blood under infiltrative and disseminated pulmonary tuberculosis. Blood mononuclear cells were isolated by gradient centrifugation, then cultured in complete culture medium; the level of IL-12β production was determined by the ELISA (ELISA). Peripheral blood served as the material of the research. It has been established, that under infiltrative pulmonary tuberculosis the levels of basal, protein and lipid-induced IL-12β production were significantly lower than in healthy donors and patients with disseminated pulmonary tuberculosis. Under disseminated pulmonary tuberculosis basal IL-12β production varies within normal limits; when stimulated by protein antigen, it increases, when influenced by lipid antigen — decreases.Проведена оценка уровня секреции IL-12β мононуклеарными лейкоцитами крови при инфильтративном и диссеминированном туберкулезе легких (ТЛ). Мононуклеары выделяли градиентным центрифугированием, культивировали в полной питательной среде, уровень продукции IL-12β определяли методом ИФА (ELISA). Установлено, что при инфильтративном ТЛ уровень базальной, белок- и липидиндуцированной продукции IL-12β значительно ниже, чем у здоровых доноров и больных диссеминированным ТЛ. При диссеминированном ТЛ базальная продукция IL-12β была в пределах нормы, при стимуляции белковым антигеном увеличивается, при действии липидного антигена — понижается

Interregional features in the taxonomic composition of the Russian segetal floras

The article contains a comparative analysis of the taxonomical structure of the weedy species composition (segetal flora) in eight regions of Russian Federation: Leningrad, Novgorod, Vologda, Rostov and Sverdlovsk Provinces, Udmurt Republic, Republic of Bashkortostan, and Altai Territory. The segetal flora comprised weeds of cereals, root crops and perennial grasses. The comparison was made separately for the native and alien weeds. The number of native species was higher than that of alien species and varied from 137 to 209 species. The number of alien weeds varied from 99 to 179 species. Vologda Province had the lowest diversity of both native and alien plant species. Udmurt Republic had the greatest native species diversity and Altai Territory had the greatest alien species diversity. The Asteraceae, Poaceae, Brassicaceae, Fabaceae, Lamiaceae, Caryophyllaceae and Scrophulariaceae families dominated in both the native and alien fractions. The authors compared the compositions of species, families and genera of native and alien weeds. Native and alien weedy species showed the greatest similarity in their composition in geographically close regions: European Russia and the Urals. As for geographically remote regions – Altai Territory and Rostov Province – native and alien weedy species compositions were distant. At the same time, the levels of similarity among the native species were lower than among the alien ones. This attests to greater variability in the species composition among native weeds than among alien ones

Strategy of students behavior during training at the Medical University

The authors present the results of the survey of students enrolled at the undergraduate medical faculty of the Urals State Medical University, the differences in the choice of behavioral strategies in the learning process, depending on gender. Also the authors show the strategy of behavior of the perceptions of the nature and properties of intelligence and personality.В работе представлены результаты анкетирования студентов, обучающихся на старших курсах лечебного факультета Уральского государственного медицинского университета. Показаны различия в выборе стратегии поведения в процессе обучения в зависимости от половой принадлежности. Также показана зависимость стратегии поведения от представлений о характере и свойствах интеллекта и личности

Strategy of students behavior during training at the Medical University

The authors present the results of the survey of students enrolled at the undergraduate medical faculty of the Urals State Medical University, the differences in the choice of behavioral strategies in the learning process, depending on gender. Also the authors show the strategy of behavior of the perceptions of the nature and properties of intelligence and personality.В работе представлены результаты анкетирования студентов, обучающихся на старших курсах лечебного факультета Уральского государственного медицинского университета. Показаны различия в выборе стратегии поведения в процессе обучения в зависимости от половой принадлежности. Также показана зависимость стратегии поведения от представлений о характере и свойствах интеллекта и личности

Генотипическая характеристика M. tuberculosis — возбудителей остропрогрессирующего деструктивного туберкулеза легких

The results of 77 M. tuberculosis clinical isolates genetic typing, allocated from patients with extensive destructive infiltrative and disseminated pulmonary tuberculosis are presented in the article. It is established that among genetically non-uniform Mycobacterium tuberculosis strains, circulating in Tomsk and the Tomsk Region, and causing acute progressive destructive pulmonary tuberculosis, 19% show multi drag resistance. Beijing family strains make 27% from the general population, have a high clusterization index (74%), level of their multi drag resistance in 3 times exceeds that at «not Beijing» strains for which the share of clustering strains makes 11%.В статье представлены результаты генетического типирования 77 клинических изолятов Mycobacterium tuberculosis, выделенных из мокроты больных распространенным деструктивным инфильтративным и диссеминированным туберкулезом легких. Установлено, что среди генетически неоднородных штаммов M. tuberculosis, циркулирующих на территории г. Томска и Томской области, вызывающих остропрогрессирующий распространенный деструктивный туберкулез легких, 19% проявляют множественную лекарственную устойчивость. Штаммы семейства Beijing (пекинская группа) составляют 27% от общей популяции возбудителя, имеют высокий показатель кластеризации (74%), уровень их множественной лекарственной устойчивости в 3 раза превышает таковой у «непекинских» штаммов, для которых доля кластеризующихся штаммов составляет 11%

Сегетальная флора некоторых регионов России: характеристика таксономической структуры

The authors' data on the weed species composition in 8 geographic regions of the Russian Federation were laid at the basis of this survey. The segetal flora comprised weeds of cereals, root crops, and perennial grasses. The composition and taxonomic structure of weed species were analyzed. The total number of weedy plants encompassed 686 plant species. The level of regional weed species diversity was positively related to the area planted. Altai Territory, Udmurtia, and Rostov Province had the greatest weed species diversity, with more than 300 species, while Vologda Province had the lowest diversity (193 species). Most species-rich plant families (Asteraceae Dumort., Poaceae Barnhart, Fabaceae Lindl., Brassicaceae Burnet), genera (Potentila L., Artemisia L., Veronica L., Chenopodium L., Silene L., Trifolium L.), their subsequences, contributions of single-species families (17-39%) and genera (57-74%) were relatively stable systematic structure indicators. Only 18% of the species were common for all the regions. In each region there were region-specific groups of species. Weed species compositions in geographically close regions - the European part of Russia and the Urals - showed the greatest similarity. As for geographically distant regions (Altai Territory and Rostov Province), their weedy species compositions were distant and contained large groups of region-specific species. © 2020 All-Russian Institute of Plant Genetic Resources -Federal Research Center. All rights reserved.This work was supported in part by the Russian Foundation for Basic Research (projects 17-44-020402 р_а, 19-016-00135), state budget funds (AAAA-A18-118011990151-7), and as part of the implementation of the state task on the topic: “Vascular plants of Eurasia: taxonomy, flora, plant resources” (AAAA-A19-119031290052-1)

Влияние противотуберкулезных препаратов резервного ряда на продукцию противовоспалительных цитокинов у больных туберкулезом легких

The results of research show the impact of ofloxacin, para-aminosalicylic acid (PASA) and capreomycin in conjunction with the BCG vaccine strain to the cytokine-production ability of mononuclear peripheral blood leukocytes for patients with infiltrative pulmonary tuberculosis prior to specific antituberculosis therapy. The results show that ofloxacin has inducing effect on the secretion of interleukin (IL) 4 and transforming growth factor (TGF) β; PASA and capreomycin have such effect for the products of IL10 and TGFβ. This influence has a negative effect during the active development of the pathological process and during specific treatment.Представлены результаты исследования влияния офлоксацина, парааминосалициловой кислоты (ПАСК) и капреомицина в комплексе с вакцинным штаммом БЦЖ на цитокинпродуцирующую способность мононуклеарных лейкоцитов периферической крови у больных инфильтративным туберкулезом легких до начала специфической противотуберкулезной терапии. Показано, что офлоксацин оказывает индуцирующие влияние на секрецию интерлейкина (interleukin — IL) 4 и трансформирующего фактора роста (transforming growth factor — TGF) β, ПАСК и капреомицин — на продукцию IL-10 и TGF-β, что в период активного развития патологического процесса и на этапе специфического лечения имеет отрицательное значение

A METHOD OF PRODUCTION A MICROFLUIDIC PAPER-BASED TEST SYSTEMS

The purpose of the work is to create a paper test system that can detect compounds by changing the fluorescence. The main goals in the design are low cost and high efficiency

Причины дисрегуляции иммунного ответа при туберкулезе легких: роль нарушений исходного состояния иммунологической реактивности организма

Genetically determinate and acquired disorders of immune reactivity in tuberculosis infection are discussed in this review. The changes in immunocompetent cells, manifested in a disorder of the structure of their cell membranes, proliferation processes, intracellular metabolism and functional activity, which cause reduced resistance of the organism to infection with Mycobacterium tuberculosis and contribute to the formation of secondary immunological deficiency in pulmonary tuberculosis are described.Рассматриваются генетически детерминированные и приобретенные нарушения иммунологической реактивности при туберкулезной инфекции. Описаны изменения в иммунокомпетентных клетках, проявляющиеся нарушением структуры их клеточных мембран, процессов пролиферации, внутриклеточного метаболизма и функциональной активности, которые обусловливают снижение устойчивости организма к заражению Mycobacterium tuberculosis и способствуют формированию вторичной иммунологической недостаточности при туберкулезе легких