Neural network modeling of Herglotz—Wiechert inversion of multiparametric travel-time curves of seismic waves

Using artificial neural networks to solve a problem of plotting travel-time curves of seismic waves can create nonlinear travel-time model of P and S phases of seismic waves arrangement as a function of several arguments: source depth, magnitude, back azimuth and epicenter distance. Construction of three-dimensional travel-time relationships and their use for modeling of hadographs and their inversion are considered on examples of seismic records Ukrainian seismic stations. Examples of inversion locus within the model Herglotz—Wiechert and features of application of the model in a real environment for single seismic stations, and generalization for arbitrary coordinate of the source and the point of signal registration in the Black Sea region are given.Використання мереж штучних нейронів у задачі побудови годографів сейсмічних хвиль дає змогу створювати нелінійні моделі поля часів поширення P- і S-фаз сейсмічних хвиль як функцій декількох аргументів: глибини розміщення вогнища, магнітуди, азимуту надходження хвиль і епіцентральної відстані. Побудову тривимірних годографів розглянуто на прикладах сейсмічних записів українських сейсмостанцій і їх використання для моделювання годографів та інверсії останніх. Наведено приклади інверсії годографа в рамках моделі Герглотца— Віхерта, а також особливості застосування моделі в реальному середовищі для одиничних сейсмостанцій і узагальнення для випадку довільних координат джерела і точки реєстрації сигналу в Чорноморському регіоні

Translation peculiarities of idioms: cultural aspect, metaphorical grounds

Idioms are found in every language and learning them is an important aspect of mastering a language. The English language is no exception as it contains a large number of idioms, which are extensively used. Due to their rigid structure and quite unpredictable meaning, idioms are often considered difficult to learnyesBelgorod State Universit

INFLUENCE OF OXYGENATOR EXTRACORPORAL CIRCUIT TREATMENT WITH ADAPTATION COMPOSITION (AdC) ON MORPHOLOGICAL CHANGES OF ERYTHROCYTES.

Summary. The study highlights a method of treatment extracorporeal circuit with «adaptation composition» (AdC) for the reduction of negative impact on state of erythrocytes. Materials and methods. A total of 90 patients were enrolled, they were divided into two groups. The group 1 (45 patients, 39/6 male/female) included patients who underwent surgical procedures without treatment of an extracorporeal circuit with AdC. The group 2 (45 patients, 39/6 male/female) included patients who underwent surgery with the treatment of an extracorporeal circuit with AdC. According to the study protocol, patient blood was sampling for complete blood cell count (CBC) and erythrocyte morphology at 4 stages of surgery: before surgery, at 10 min. CPB-time, at 60 min. CPB-time and after separation from CPB. Results. The albumin of AdC creates a protective nanolayer on the surface of the oxygenator membrane and tubes. There were no statistically significant differences of parameters in the groups before CPB. Level of Ht 2 (group 2) at 60 min CPB-time and after CPB, were lower than Ht 1 (group 1) (p=0.021 and p=0.035 correspondingly) because MCV1 was higher (р=0.025 and p<0.0001 correspondingly). The increase MCHC in groups at 10 min. CPB-time relatives with the decrease in MCV at 10 min CPB-time. At 60 min, there are changes of RDWa2 76.05 ± 5.46 and RDWa1 72.35 ± 7.26, p<0.000. After CPB higher content of reticulocytes (р <0.0001), echinocytes (р <0.0001) and spherocytes (р <0.0001) is observed in group 1. The lowering of mechanical resistance (р = 0.04) and increasing membrane permeability for urea were in group 1. After CPB the best aсid hemolysis resistance was in group 2 (р = 0.05), erythrocytes were more resistant to hypoosmotic factor (р = 0.01) in group 2. Conclusion. The treatment of oxygenator with AdC reduces the negative influence СРВ on state of RBC. Membranes of erythrocytes were more resistant to traumatic factors in the group with AdC.В роботі висвітлюється метод обробки экстракорпорального контура оксигенатора «адаптуючою композицією» (adaptation composition – AdC) для зменшення негативного впливу штучного кровообігу на стан еритроцитів. Матеріали і методи. В дослідження було включено 90 пациентов, які були розподілені на дві групи. Пацієнтам першої групи (45 хворих, 39/6 чол./жін.) оперативні втручання виконували без обробки контуру оксигенатору адаптуючою композицією (AdC). Оперативні втручання у пацієнтів другої групи (45 пацієнтів - 36/9 чол./жін.) проводились з обробкою AdC. Згідно протоколу дослідження, у пацієнтів набирали кров для загального аналізу крові та морфологічного дослідження еритроцитів на 4 етапах оперативного втручання: до початку операції, на 10 хв. ШК, на 60 хв. ШК та в кінці операції. Результати та їх обговорення. Альбумін в складі AdС створює наношар на поверхні магистралей та мембрани оксигенатора. Між групами до ШК не було статистично значущої різниці у показниках. Рівень Ht 2 (група 2) на 60 хв. ШК ти після ШК був нижче, ніж Ht 1 (група 1) (p=0,021 і p=0,035 відповідно) через зібльшення MCV 1 (р=0,025 і p <0,0001 відповідно). На 10 хв. ШК підвищення МСНС в групах пов'язано зі зниженням MCV на 10 хв. ШК. На 60 хв. від початку ШК відбувається зміна в RDWа2 76,05 ± 5,46 і RDWа1 72,35 ± 7,26, р <0,0001. Після ШК в групі 1 визначається більш високий вміст ретикулоцитів (р <0,0001), ехіноцитів (р <0,0001) і сфероцитів (р <0,0001). В групі 1 після ШК відбувається зниження механічної стійкості еритроцитів (р = 0,04) та підвищена проникність мембрани еритроцитів для сечовини. Після ШК більша резистентність еритроцитів до кислотного гемолізу була в групі 2 (р = 0,05), також в групі 2 еритроцити були більш стійкими до гіпоосмотичному фактору (р = 0,01). Висновки. Обробка оксигенатора адаптуючою композицією призводить до зменшення негативного впливу ШК на стан еритроцитів. Мембрани еритроцитів були більш резистентні до дії факторів що ушкоджують в групі з використанням AdC

Neural network modeling of Herglotz—Wiechert inversion of multiparametric travel-time curves of seismic waves

Using artificial neural networks to solve a problem of plotting travel-time curves of seismic waves can create nonlinear travel-time model of P and S phases of seismic waves arrangement as a function of several arguments: source depth, magnitude, back azimuth and epicenter distance. Construction of three-dimensional travel-time relationships and their use for modeling of hadographs and their inversion are considered on examples of seismic records Ukrainian seismic stations. Examples of inversion locus within the model Herglotz—Wiechert and features of application of the model in a real environment for single seismic stations, and generalization for arbitrary coordinate of the source and the point of signal registration in the Black Sea region are given.Використання мереж штучних нейронів у задачі побудови годографів сейсмічних хвиль дає змогу створювати нелінійні моделі поля часів поширення P- і S-фаз сейсмічних хвиль як функцій декількох аргументів: глибини розміщення вогнища, магнітуди, азимуту надходження хвиль і епіцентральної відстані. Побудову тривимірних годографів розглянуто на прикладах сейсмічних записів українських сейсмостанцій і їх використання для моделювання годографів та інверсії останніх. Наведено приклади інверсії годографа в рамках моделі Герглотца— Віхерта, а також особливості застосування моделі в реальному середовищі для одиничних сейсмостанцій і узагальнення для випадку довільних координат джерела і точки реєстрації сигналу в Чорноморському регіоні

Thermogravimetric Analysis of Indicators of the Paste Based on Sour Cream

For forming structural-mechanical properties of sour milk pastes and guaranteeing their stability at storage, it is promising to use non-fried buckwheat in their recipes that allows to raise the food value of products additionally. The aim of the researches was the study of features of the condition of moisture of sour milk pastes, based on sour cream with introducing non-fried buckwheat in the amount 5,0 % of the mixture mass. A sample with modified starch Е 1410 was taken as a control in the amount 1,3 %.The study of the moisture condition was realized by the thermogravimetric method using a derivatograph Q-1500D (Paulik-Erdey) (Hungry). It was established, that the content of adsorptive moisture of the sour milk paste was 34,0 %, whereas in the control – 34,5 %, that confirm the effectiveness of using non-fried buckwheat as a moisture-binding component. Such properties of non-fried buckwheat may be explained by the presence of starch compounds and easily accessible protein in its composition, able to hydration in the process of preparation of a component and to keeping moisture at further storage of a product

Evaluation of the state of medical care in patients with arterial hypertension in combination with gout by retrospective analysis data.

The prevalence of cardiovascular diseases, especially arterial hypertension, continues to increase. An important problem is the management of the patient with a comorbid pathology in the primary link by the family physician. The purpose of this study was to assess the state of medical care in patients with arterial hypertension combined with gout, using a retrospective analysis of ambulatory cards, diagnostic and treatment data. There were analyzed 105 outpatient cards that met the inclusion criteria. The mean age of patients was 53.5±10.2 years. Among the examined patients there were 99 males (94.3%), and 6 (5.7%)females. Аrterial hypertension stage II has been reported in 100 (95.2%) patients, stage III – 5 (4.8%) patients. Аrterial hypertension 1 degree is established in 74 (70,5%) patients, 2 degrees – 21 (20%), 3 degrees – 10 (9,5%). The average duration of the gout was 4.4 [4; 2] years, arterial hypertension – 5.3 [3; 1] years. Acute gouty arthritis was present in 11 (10.5%) patients, chronic gouty arthritis – 85 (81%), and chronic tofi arthritis – 9 (8.5%). Patients seek medical help from their family doctor too late. Examination of patients with hypertension in combination with gout is not complete, this contributes to underestimation of total cardiovascular risk. In a number of cases, titration of the dose of allopurinol higher than 300 mg is not, performed so only a third of patients reach the target uric acid level

The role of assessment of quality of life and health with the index of vital activity in patients with arterial hypertension combined with gout in the family doctor practice.

The number of studies that assess the quality of life of patients with various comorbid diseases is increasing annually. Arterial hypertension and gout is no exception. There are difficulties in managing this category of patients at the primary stage in accordance with current recommendations. The purpose of the study was to analyze the effectiveness of use of questionnaires for assessing the quality of life (SF-36) and health (HAQ) with disability index (DI) in patients with arterial hypertension combined with gout in everyday clinical practice by the family doctor; to assess the correctness of maintaining this category of patients in accordance with current recommendations (EULAR, 2016). A sociological survey of general practitioners (n=30) was carried out by a specially developed questionnaire consisting of three sections. It was found that not all doctors prescribe an adequate dose of colchicine for exacerbation of gouty arthritis, and more than half of the doctors do not use preventive colchicine for 3-6 months after the attack. Most doctors do not use the assessment quality of life (SF-36) and Health Assessment Questionare (HAQ) with a disability index (DI) at admission, but most believe that the results of these questionnaires contain important information on the patient's condition and the prospects for their using at the outpatient stage

Magnetic force microscopy of atherosclerotic plaque.

In this work by methods of scanning probe microscopy, namely by atomic force microscopy and magnetic force microscopy the fragments of atherosclerotic plaque section of different nature were investigated. The fragments of atherosclerotic vessels with elements of immature plaque were taken during the coiled artery bypass surgery by alloprosthesis. As the result of investigation we found magnetically ordered phase of endogenous origin in the fragment of solid plaque of mixed structure. This phase is presents biogenic magnetic nanoparticles and their clusters with average size characteristic of 200-400 nm

Transformation of the Established Object-Spatial Environment of the Student Hostel

The inconsistency of the existing subject-spatial environment of typical student dormitories, built in the XX century, with the modern requirements of students'socialization during their studies at the university is revealed. Improving the comfort of living without reconstruction of hostels is possible due to the transformation of the subject environment. The developed plans for minimum redevelopment of floors, subject filling of the spatial environment of living rooms, taking into account anthropological, ergonomic, environmental requirements, will provide students with comfortable living

Antimicrobial and therapeutic effect of probiotics in cases of experimental purulent wounds

Probiotics based on bacteria of the genus Bacillus with a multifactorial mechanism of action are considered as a possible alternative to antibiotics in the treatment of purulent wounds. The aim of the study was to determine the antimicrobial and therapeutic effect of the Arederma probiotic preparation containing probiotic strains of the genus Bacillus in an experimental model of a purulent wound in animals. The antimicrobial efficacy of the probiotic against test strains and clinical isolates of pathogenic and opportunistic microorganisms was studied using the method of delayed antagonism. Staphylococcus aureus ATCC 6538 and Streptococcus pyogenes K-7 were used to model a purulent wound. From the surface of the wounds, bacteria of Staphylococcus, Streptococcus, Enterobacteriaceae, Pseudomonas genera and Enterobacteriaceae family were sown on appropriate selective media for the cultivation and enumeration of different groups of microorganisms by generally accepted microbiological research methods. The formation of a purulent wound in rabbits caused by mechanical skin damage and subsequent double infection with Staphylococcus aureus ATCC 6538 and Streptococcus pyogenes K-7 strains was accompanied with a pronounced inflammatory process, necrosis, the formation of purulent exudate and general intoxication. Representatives of the genera Staphylococcus and Streptococcus, microscopic fungi and, to a lesser extent, members of the family Enterobacteriaceae and Pseudomonas were found on the surface of purulent wounds, which confirmed the development of the infectious-inflammatory process. Treatment of purulent wounds with a suspension of probiotic preparation once a day for 4 days led to their faster healing (gradual attenuation of the inflammatory process, reduction of edema and discharge, as well as their disappearance) compared with untreated purulent wounds (control). Representatives of the Staphylococcus and Streptococcus genera, as well as microscopic fungi, presented in purulent wounds treated with probiotic preparation in much smaller numbers than in the control, and bacteria of the Pseudomonas genus and the Enterobacteriaceae family were not detected at all. The effective antimicrobial effect of this probiotic preparation against opportunistic and pathogenic microorganisms was confirmed by in vitro studies. Therefore, the Arederma probiotic preparation showed an effective therapeutic and antimicrobial effect in the experimental model of a purulent wound in animals, so it can be recommended for further preclinical and clinical studies