19,728 research outputs found

    Is Accurate Understanding of Global Warming Necessary to Promote Willingness to Sacrifice?

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    Although not definitive, the authors\u27 study suggests potential benefits from having a general public better informed about global climate change. They find, e.g., that accurate information appears to increase willingness to accept personal sacrifice

    Poly(ADP-Ribose) Polymerase 1 Accelerates Single-Strand Break Repair in Concert with Poly(ADP-Ribose) Glycohydrolase

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    Single-strand breaks are the commonest lesions arising in cells, and defects in their repair are implicated in neurodegenerative disease. One of the earliest events during single-strand break repair (SSBR) is the rapid synthesis of poly(ADP-ribose) (PAR) by poly(ADP-ribose) polymerase (PARP), followed by its rapid degradation by poly(ADP-ribose) glycohydrolase (PARG). While the synthesis of poly(ADP-ribose) is important for rapid rates of chromosomal SSBR, the relative importance of poly(ADP-ribose) polymerase 1 (PARP-1) and PARP-2 and of the subsequent degradation of PAR by PARG is unclear. Here we have quantified SSBR rates in human A549 cells depleted of PARP-1, PARP-2, and PARG, both separately and in combination. We report that whereas PARP-1 is critical for rapid global rates of SSBR in human A549 cells, depletion of PARP-2 has only a minor impact, even in the presence of depleted levels of PARP-1. Moreover, we identify PARG as a novel and critical component of SSBR that accelerates this process in concert with PARP-1

    Coupled Fluctuations near Critical Wetting

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    Recent work on the complete wetting transition has emphasized the role played by the coupling of fluctuations of the order parameter at the wall and at the depinning fluid interface. Extending this approach to the wetting transition itself we predict a novel crossover effect associated with the decoupling of fluctuations as the temperature is lowered towards the transition temperature T_W. Using this we are able to reanalyse recent Monte-Carlo simulation studies and extract a value \omega(T_W)=0.8 at T_W=0.9T_C in very good agreement with long standing theoretical predictions.Comment: 4 pages, LaTex, 1 postscript figur

    Gas-liquid critical point in ionic fluids

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    Based on the method of collective variables we develop the statistical field theory for the study of a simple charge-asymmetric 1:z1:z primitive model (SPM). It is shown that the well-known approximations for the free energy, in particular DHLL and ORPA, can be obtained within the framework of this theory. In order to study the gas-liquid critical point of SPM we propose the method for the calculation of chemical potential conjugate to the total number density which allows us to take into account the higher order fluctuation effects. As a result, the gas-liquid phase diagrams are calculated for z=24z=2-4. The results demonstrate the qualitative agreement with MC simulation data: critical temperature decreases when zz increases and critical density increases rapidly with zz.Comment: 18 pages, 1 figur

    Possible effects of charge frustration in Nax_xCoO2_2: bandwidth suppression, charge orders and resurrected RVB superconductivity

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    Charge frustration due to further neighbor Coulomb repulsion can have dramatic effects on the electronic properties of Nax_xCoO2_2 in the full doping range. It can significantly reduce the effective mobility of the charge carriers, leading to a low degeneracy temperature ϵFT\epsilon_F \lesssim T. Such strongly renormalized Fermi liquid has rather unusual properties--from the point of view of the ordinary metals with ϵFT\epsilon_F \gg T--but similar to the properties that are actually observed in the Nax_xCoO2_2 system. For example, we show that the anomalous thermopower and Hall effect observed in Na0.7_{0.7}CoO2_2 may be interpreted along these lines. If the repulsion is strong, it can also lead to charge order; nevertheless, away from the commensurate dopings, the configurational constraints allow some mobility for the charge carriers, i.e., there remains some ``metallic'' component. Finally, the particularly strong bandwidth suppression around the commensurate x=1/3x=1/3 can help resurrect the RVB superconductivity, which would otherwise not be expected near this high doping. These suggestions are demonstrated specifically for a tJtJ-like model with an additional nearest neighbor repulsion.Comment: 15 pages, 17 figure

    Thermodynamic properties of spin-1/2 transverse XY chain with Dzyaloshinskii-Moriya interaction: Exact solution for correlated Lorentzian disorder

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    We extend the consideration of the spin-1/2 transverse XY chain with correlated Lorentzian disorder (Phys. Rev. B {\bf 55,} 14298 (1997)) for the case of additional Dzyaloshinskii-Moriya interspin interaction. It is shown how the averaged density of states can be calculated exactly. Results are presented for the density of states and the transverse magnetization.Comment: 2 figure

    Expansion dynamics of Lennard-Jones systems

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    The dynamics of the expansion of a Lennard-Jones system, initially confined at high density and subsequently expanding freely in the vacuum, is confronted to an expanding statistical ensemble, derived in the diluted quasi-ideal Boltzmann approximation. The description proves to be fairly accurate at predicting average one-body global observables, but important deviations are observed in the configuration-space structure of the events. Possible implications for finite expanding physical systems are outlined

    Mapping the phase diagram of strongly interacting matter

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    We employ a conformal mapping to explore the thermodynamics of strongly interacting matter at finite values of the baryon chemical potential μ\mu. This method allows us to identify the singularity corresponding to the critical point of a second-order phase transition at finite μ\mu, given information only at μ=0\mu=0. The scheme is potentially useful for computing thermodynamic properties of strongly interacting hot and dense matter in lattice gauge theory. The technique is illustrated by an application to a chiral effective model.Comment: 5 pages, 3 figures; published versio

    Ionic fluids: charge and density correlations near gas-liquid criticality

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    The correlation functions of an ionic fluid with charge and size asymmetry are studied within the framework of the random phase approximation. The results obtained for the charge-charge correlation function demonstrate that the second-moment Stillinger-Lovett (SL) rule is satisfied away from the gas-liquid critical point (CP) but not, in general, at the CP. However in the special case of a model without size assymetry the SL rules are satisfied even at the CP. The expressions for the density-density and charge-density correlation functions valid far and close to the CP are obtained explicitely

    Criticality and phase separation in a two-dimensional binary colloidal fluid induced by the solvent critical behavior

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    We present an experimental and theoretical study of the phase behavior of a binary mixture of colloids with opposite adsorption preferences in a critical solvent. As a result of the attractive and repulsive critical Casimir forces, the critical fluctuations of the solvent lead to a further critical point in the colloidal system, i.e. to a critical colloidal-liquid--colloidal-liquid demixing phase transition which is controlled by the solvent temperature. Our experimental findings are in good agreement with calculations based on a simple approximation for the free energy of the system.Comment: 5 pages, 5 figures, to be published in Europhysics Letter
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