1,690 research outputs found

    Factors Used to Determine the Teaching Load for Chairs in Public Community Colleges

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    After a 10 minute presentation of a recently completed national study of the practices used by public community colleges to determine chair teaching load, attendees will be provided a framework and procedure for determining chair teaching load on their campus, and will then engage in a spirited but structured discussion of the factors to be considered and a process for assigning weights to each

    Legal Crib Sheets: Promoting Deep Levels of Processing and Learning

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    The article demonstrates that legal crib sheets encourage deep levels of information processing, an activity that should enhance students\u27 learning and long-term memory. Levels of processing theory states that memory processes exist on a depth continuum; comprehension and synthesis are examples of deep cognitive processes that enhance memory, whereas simple repetition or examining surface characteristics of words are examples of shallow cognitive processes (Craik & Lockhart, 1972). The use of legal crib sheets allowed students to attain significantly higher overall mean test scores while not affecting their long-term retention of the material. Deeper levels of processing occurred because the students manipulated course infOrmation in preparing legal crib sheets

    Fluorescent Chemosensors for Toxic Organophosphorus Pesticides: A Review

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    Many organophosphorus (OP) based compounds are highly toxic and powerful inhibitors of cholinesterases that generate serious environmental and human health concerns. Organothiophosphates with a thiophosphoryl (P=S) functional group constitute a broad class of these widely used pesticides. They are related to the more reactive phosphoryl (P=O) organophosphates, which include very lethal nerve agents and chemical warfare agents, such as, VX, Soman and Sarin. Unfortunately, widespread and frequent commercial use of OP-based compounds in agricultural lands has resulted in their presence as residues in crops, livestock, and poultry products and also led to their migration into aquifers. Thus, the design of new sensors with improved analyte selectivity and sensitivity is of paramount importance in this area. Herein, we review recent advances in the development of fluorescent chemosensors for toxic OP pesticides and related compounds. We also discuss challenges and progress towards the design of future chemosensors with dual modes for signal transduction. © 2010 by the authors; licensee MPDI, Basel, Switzerland

    Continuous-flow left ventricular assist device outflow graft stenting: Indications and outcomes

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    Introduction: Stenosis in the continuous-flow left ventricular assist device (CF-LVAD) outflow graft can be caused by various mechanical and anatomical factors. Increasingly, percutaneous management has been utilized to re-establish adequate CF-LVAD flow. We sought to evaluate indications for such interventions and their outcomes. Methods: An electronic search was performed to identify all studies in the English literature reporting CF-LVAD outflow graft stenting for various etiologies. Twenty-one studies consisting of 26 patients were included in the analysis. Results: Median patient age was 59 years [45.8-67.0] and 65.4% (17/26) were male. 58.3% (14/24) of patients had HeartWare HVAD, 37.5% (9/24) had HeartMate II LVAD, and 4.2% (1/24) had HeartMate III LVAS. Median time from device placement to outflow graft stenting was 24.0 months [7.8-30.4]. 76.9% of patients (20/26) presented with heart failure. 34.6% (9/26) had outflow graft thrombosis, 34.6% (9/26) stenosis, 11.5% (3/26) kinking, 11.5% (3/26) pseudoaneurysm, 3.8% (1/26) external graft compression, and 3.8% (1/26) had a bronchialarterial fistula. 88.5% (23/26) procedures led to immediate flow improvement with the remaining 11.5% (3/26) receiving additional stenting. Post-intervention flows were significantly improved (4.7 L/min [4.1-4.8] post-intervention vs 2.9 L/min [2.0-3.5] initial, p=0.01). 96.2% (25/26) patients were discharged from the hospital. The 30-day mortality was 6.7% (1/15). Overall mortality during the median follow-up of 90 days [7.0-240.0] was 9.5% (2/21). Discussion: Outflow graft stenting appears to effectively alleviate CF-LVAD outflow graft obstruction with low mortality. Longer-term follow up is necessary to determine the longevity of such an intervention but early results are promising

    Molecular hierarchy of mammary differentiation yields refined markers of mammary stem cells

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    The partial purification of mouse mammary gland stem cells (MaSCs) using combinatorial cell surface markers (Lin-CD24+CD29hCD49fh) has improved our understanding of their role in normal development and breast tumorigenesis. Despite the significant improvement in MaSC enrichment, there is presently no methodology that adequately isolates pure MaSCs. Seeking new markers of MaSCs, we characterized the stem-like properties and expression signature of label-retaining cells from the mammary gland of mice expressing a controllable H2b-GFP transgene. In this system, the transgene expression can be repressed in a doxycycline-dependent fashion, allowing isolation of slowly dividing cells with retained nuclear GFP signal. Here, we show that H2b-GFPh cells reside within the predicted MaSC compartment and display greater mammary reconstitution unit frequency compared with H2b-GFPneg MaSCs. According to their transcriptome profile, H2b-GFPh MaSCs are enriched for pathways thought to play important roles in adult stem cells. We found Cd1d, a glycoprotein expressed on the surface of antigen-presenting cells, to be highly expressed by H2b-GFPh MaSCs, and isolation of Cd1d+ MaSCs further improved the mammary reconstitution unit enrichment frequency to nearly a single-cell level. Additionally, we functionally characterized a set of MaSC-enriched genes, discovering factors controlling MaSC survival. Collectively, our data provide tools for isolating a more precisely defined population of MaSCs and point to potentially critical factors for MaSC maintenance

    The association of nutrition behaviors and physical activity with general and central obesity in Caribbean undergraduate students

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    Objective. To quantify the prevalence of obesity and obesity-related factors in a cross-sectional, observational study of Caribbean students using the results of three recent surveys of health behavior among undergraduates in Barbados, Grenada, and Jamaica. Methods. A total of 1578 Caribbean undergraduate students from Barbados, Grenada, and Jamaica (ages 18.30 years) completed questionnaires and had physical measurements recorded. Multivariable logistic regression was used to estimate odds ratios (ORs) for the association of nutrition behaviors with prevalence of obesity (body mass index ≥ 30 kg/m2); elevated waist-to-height ratio (W/ht) (> 0.50); and high waist circumference (WC) (> 88 cm in females, > 102 cm in males). Models were adjusted for age, year in university, socioeconomic status, and sex. Results. There was a higher prevalence of obesity (13% versus 10%), high WC (21% versus 7%), and high W/ht (35% versus 25%) in females relative to males. Compared to females, males had reduced odds of obesity (OR 0.46), high WC (OR 0.22), and high W/ht (OR 0.61) (P < 0.05 for all). Both females (46%) and males (24%) reported high levels of physical inactivity. Fruit and vegetable consumption was low (approximately two servings per day). Many students reported avoiding fatty foods (40%); this behavior was associated with high W/ht (OR 1.68), obesity (OR 1.90), and high WC (OR 1.82) (P < 0.05 for all). Irregular breakfast consumption, age, and year of study were also positively associated with obesity. Physical activity was not significantly associated with any obesity measure. Conclusions. There was a low prevalence of healthy behaviors and a high prevalence of obesity in this sample of Caribbean young adults

    Dissipative dynamics of vortex lines in superfluid 4^{4}He

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    We propose a Hamiltonian model that describes the interaction between a vortex line in superfluid 4^{4}He and the gas of elementary excitations. An equation of irreversible motion for the density operator of the vortex, regarded as a macroscopic quantum particle with a finite mass, is derived in the frame of Generalized Master Equations. This enables us to cast the effect of the coupling as a drag force with one reactive and one dissipative component, in agreement with the assumption of the phenomenological theories of vortex mutual friction in the two fluid model.Comment: 16 pages, no figures, to be published in PR
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