Fósiles ordovícicos del NO de Adamuz (Córdoba): aportación paleobiogeográfica a la concepción del limite entre las Zonas Centroibérica y Ossa Morena durante el Paleozoico

The Ordovician outcrop at NW Adamuz (Cordoba province), previously regarded as belonging to in the Ossa Morena Zone by some authors, contains several fossiliferous levels of Lower Llanvirn, Upper Llanvirn-Llandeilo and Caradoc (pre-Actonian) age. The Central Iberian affinities of the faunas constitute an additional argument for the consideration of the Obejo-Valsequillo-Puebla de la Reina Domain as the southern margin of the Central Iberian Zone during the Paleozoic

Geotraverse south (B-1) : (excursion guidebook. Day 1)

The purpose of this excursion is to make a quick geological reconnaissance of the main stratigraphic and tectonic characteristics of the terranes in the southern part of the Iberian Peninsula, starting with the Alcudian Terrane (days 1 and 2), Obejo-Valseguillo (day 2), Hornachos (day 2), Valencia de las Torres (day 3), Sierra Albarrana (day 3), Olivenza-Monesterio (days 4 and 5), Barrancos (day 5), Aracena (day 5), Pule do Lobo (day 5), and South Portuguese (day 6), by visiting strategic outcrops where the main points and problems can be discussed

Fósiles ordovícicos del NO de Adamuz (Córdoba): aportación paleobiogeográfica a la concepción del Iímite entre las Zonas Centroibérica y Ossa Morena durante el Paleozoico

3 páginas, 1 figura.-- Trabajo presentado en la 4ª Sesión Científica, Granada 1987.The Ordovician outcrop at NW Adamuz (Córdoba province), previously regarded as belonging to in the Ossa Morena Zone by some authors, contains several fossiliferous levels of Lower Llanvirn, Upper Llanvirn-Llandeilo and Caradoc (pre-Actonian) age. The Central lberian affinities of the faunas constitute an additional argument for the consideration of the Obejo-Valsequillo-Puebla de la Reina Domain as the southern margin of the Central Iberian Zone during the Paleozoic.Este artículo es una contribución al Proyecto "Bioestratigrafia y Paleocología del Paleozoico inferior del SO, del Macizo Hespérico", financiado por el CSIC-CAICYT.Peer reviewe

Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation.

Single-cell technologies are revolutionizing biology but are today mainly limited to imaging and deep sequencing. However, proteins are the main drivers of cellular function and in-depth characterization of individual cells by mass spectrometry (MS)-based proteomics would thus be highly valuable and complementary. Here, we develop a robust workflow combining miniaturized sample preparation, very low flow-rate chromatography, and a novel trapped ion mobility mass spectrometer, resulting in a more than 10-fold improved sensitivity. We precisely and robustly quantify proteomes and their changes in single, FACS-isolated cells. Arresting cells at defined stages of the cell cycle by drug treatment retrieves expected key regulators. Furthermore, it highlights potential novel ones and allows cell phase prediction. Comparing the variability in more than 430 single-cell proteomes to transcriptome data revealed a stable-core proteome despite perturbation, while the transcriptome appears stochastic. Our technology can readily be applied to ultra-high sensitivity analyses of tissue material, posttranslational modifications, and small molecule studies from small cell counts to gain unprecedented insights into cellular heterogeneity in health and disease

Detrital zircon geochronology of the Cretaceous succession from the Iberian Atlantic Margin: palaeogeographic implications

Detrital zircon U–Pb data performed on eight Cretaceous sandstone samples (819 age isotopic results) from the Lusitanian basin (west Portugal) constrain the history of uplift and palaeodrainage of western Iberia following break-up of Pangaea and opening of the North Atlantic Ocean. We examined the links between shifts in provenance and known basinwide unconformities dated to the late Berriasian, Barremian, late Aptian and Cenomanian–Turonian. The detrital zircon record of sedimentary rocks with wider supplying areas is relatively homogenous, being characterized by a clear predominance of late Palaeozoic ages (c. 375–275 Ma) together with variable proportions of ages in the range c. 800–460 Ma. These two groups of ages are diagnostic of sources within the Variscan Iberian Massif. A few samples also reveal significant amounts of middle Palaeozoic (c. 420–385 Ma) and late Mesoproterozoic to early Neoproterozoic (c. 1.2–0.9 Ga) zircon, which are almost absent in the basement to the east of the Lusitanian basin, but are common in terranes with a Laurussia affinity found in NW Iberia and the conjugate margin (Newfoundland). The Barremian unconformity marks a sudden rise in the proportion of c. 375–275 Ma zircon ages accompanied by a decrease in the abundance of the c. 420–385 Ma and c. 1.2–0.9 Ga ages. This shift in the zircon signature, which is contemporaneous with the separation of the Galicia Bank from Flemish Cap, reflects increased denudation of Variscan crystalline rocks and a reduction in source material from NW Iberia and adjoining areas. The late Aptian unconformity, which represents the largest hiatus in the sedimentary record, is reflected by a shift in late Palaeozoic peak ages from c. 330–310 Ma (widespread in Iberia) to c. 310–290 Ma (more frequent in N Iberia). It is considered that this shift in the age spectra resulted from a westward migration of catchment areas following major uplift in northern Iberia and some transport southward from the Bay of Biscay under the influence of a well-established Atlantic circulation