13,318 research outputs found
Low-density genotype panel for both parentage verification and discovery in a multi-breed sheep population
peer-reviewedThe generally low usage of artificial insemination and single-sire mating in sheep, compounded by mob lambing (and lambing outdoors), implies that parentage assignment in sheep is challenging. The objective here was to develop a low-density panel of single nucleotide polymorphisms (SNPs) for accurate parentage verification and discovery in sheep. Of particular interest was where SNP selection was limited to only a subset of chromosomes, thereby eliminating the ability to accurately impute genome-wide denser marker panels. Data used consisted of 10,933 candidate SNPs on 9,390 purebred sheep. These data consisted of 1,876 validated genotyped sire–offspring pairs and 2,784 validated genotyped dam–offspring pairs. The SNP panels developed consisted of 87 SNPs to 500 SNPs. Parentage verification and discovery were undertaken using 1) exclusion, based on the sharing of at least one allele between candidate parent–offspring pairs, and 2) a likelihood-based approach. Based on exclusion, allowing for one discordant offspring–parent genotype, a minimum of 350 SNPs was required when the goal was to unambiguously identify the true sire or dam from all possible candidates. Results suggest that, if selecting SNPs across the entire genome, a minimum of 250 carefully selected SNPs are required to ensure that the most likely selected parent (based on the likelihood approach) was, in fact, the true parent. If restricting the SNPs to just a subset of chromosomes, the recommendation is to use at least a 300-SNP panel from at least six chromosomes, with approximately an equal number of SNPs per chromosome
Towards a Coulomb gas of instantons in the SO(4)xU(1) Higgs model on R_4
The Higgs model on is extended by a term so
that the action receives a nonvanishing contribution from the interactions of
2-instantons and 3-instantons, and can be expressed as the inverse of the
Laplacian on in terms of the mutual distances of the instantons. The
one-instanton solutions of both the basic and the extended models have been
studied in detail numerically.Comment: 29 pages LaTeX, 4 Figures available from authors on reques
Towards predicting post-editing productivity
Machine translation (MT) quality is generally measured via automatic metrics, producing scores that have no meaning for translators who are required to post-edit MT output or for project managers who have to plan and budget for transla- tion projects. This paper investigates correlations between two such automatic metrics (general text matcher and translation edit rate) and post-editing productivity. For the purposes of this paper, productivity is measured via processing speed and cognitive measures of effort using eye tracking as a tool. Processing speed, average fixation time and count are found to correlate well with the scores for groups of segments. Segments with high GTM and TER scores require substantially less time and cognitive effort than medium or low-scoring segments. Future research involving score thresholds and confidence estimation is suggested
All-optical memory based on the injection locking bistability of a two-color laser diode
We study the injection locking bistability of a specially engineered
two-color semiconductor Fabry-Perot laser. Oscillation in the uninjected
primary mode leads to a bistability of single mode and two-color equilibria.
With pulsed modulation of the injected power we demonstrate an all-optical
memory element based on this bistability, where the uninjected primary mode is
switched with 35 dB intensity contrast. Using experimental and theoretical
analysis, we describe the associated bifurcation structure, which is not found
in single mode systems with optical injection.Comment: 5 pages, 5 figure
Changing social contracts in climate-change adaptation
Risks from extreme weather events are mediated through
state, civil society and individual action
1
,
2
. We propose evolving
social contracts as a primary mechanism by which adaptation
to climate change proceeds. We use a natural experiment
of policy and social contexts of the UK and Ireland affected
by the same meteorological event and resultant flooding in
November 2009. We analyse data from policy documents and
from household surveys of 356 residents in western Ireland and
northwest England. We find significant differences between
perceptions of individual responsibility for protection across
the jurisdictions and between perceptions of future risk from
populations directly affected by flooding events. These explain
differences in stated willingness to take individual adaptive
actions when state support retrenches. We therefore show
that expectations for state protection are critical in mediating
impacts and promoting longer-term adaptation. We argue
that making social contracts explicit may smooth pathways to
effective and legitimate adaptation
The Governance of Globalization: The Political Economy of Anglo-American Hegemony, 1793-2003
Modern globalization (which includes free flows of trade and factors of production across frontiers, stable rates of exchange, the containment of warfare and mercantilism, the preservation of the environment and latterly the protection of cities against rogue states and terrorism) are among the public goods provided for the world economy as a whole are represented as a beginning outcome of 6 decades of "hegemony" exercised by governments in Washington from l941 to 2003. The view promulgated largely by Anglo-American social scientists that the United Kingdom (and before that other powers) also supplied significant public goods for the international order has been degraded in this paper into theory without history. In short the assertion that American Hegemony can be perceived as a succession to the Pax Britannica from l793-l914 is virtually a myth.
Take a stand on your decisions, or take a sit: posture does not affect risk preferences in an economic task
Physiological and emotional states can affect our decision-making processes, even when these states are seemingly insignificant to the decision at hand. We examined whether posture and postural threat affect decisions in a non-related economic domain. Healthy young adults made a series of choices between economic lotteries in various conditions, including changes in body posture (sitting vs. standing) and changes in elevation (ground level vs. atop a 0.8-meter-high platform). We compared three metrics between conditions to assess changes in risk-sensitivity: frequency of risky choices, and parameter fits of both utility and probability weighting parameters using cumulative prospect theory. We also measured skin conductance level to evaluate physiological response to the postural threat. Our results demonstrate that body posture does not significantly affect decision making. Secondly, despite increased skin conductance level, economic risk-sensitivity was unaffected by increased threat. Our findings indicate that economic choices are fairly robust to the physiological and emotional changes that result from posture or postural threat
Observation of quantum interference as a function of Berry's phase in a complex Hadamard optical network
Emerging models of quantum computation driven by multi-photon quantum
interference, while not universal, may offer an exponential advantage over
classical computers for certain problems. Implementing these circuits via
geometric phase gates could mitigate requirements for error correction to
achieve fault tolerance while retaining their relative physical simplicity. We
report an experiment in which a geometric phase is embedded in an optical
network with no closed-loops, enabling quantum interference between two photons
as a function of the phase.Comment: Comments welcom
Antiphase dynamics in a multimode semiconductor laser with optical injection
A detailed experimental study of antiphase dynamics in a two-mode
semiconductor laser with optical injection is presented. The device is a
specially designed Fabry-Perot laser that supports two primary modes with a THz
frequency spacing. Injection in one of the primary modes of the device leads to
a rich variety of single and two-mode dynamical scenarios, which are reproduced
with remarkable accuracy by a four dimensional rate equation model. Numerical
bifurcation analysis reveals the importance of torus bifurcations in mediating
transitions to antiphase dynamics and of saddle-node of limit cycle
bifurcations in switching of the dynamics between single and two-mode regimes.Comment: 7 pages, 9 figure
Lens or Binary? Chandra Observations of the Wide Separation Broad Absorption Line Quasar Pair UM425
We have obtained a 110 ksec Chandra ACIS-S exposure of UM425, a pair of QSOs
at z=1.47 separated by 6.5 arcsec, which show remarkably similar emission and
broad absorption line (BAL) profiles in the optical/UV. Our 5000 count X-ray
spectrum of UM425A (the brighter component) is well-fit with a power law
(photon spectral index Gamma=2.0) partially covered by a hydrogen column of
3.8x10^22 cm^-2. The underlying power-law slope for this object and for other
recent samples of BALQSOs is typical of radio-quiet quasars, lending credence
to the hypothesis that BALs exist in every quasar. Assuming the same Gamma for
the much fainter image of UM425B, we detect an obscuring column 5 times larger.
We search for evidence of an appropriately large lensing mass in our Chandra
image and find weak diffuse emission near the quasar pair, with an X-ray flux
typical of a group of galaxies at redshift z ~ 0.6. From our analysis of
archival HST WFPC2 and NICMOS images, we find no evidence for a luminous
lensing galaxy, but note a 3-sigma excess of galaxies in the UM425 field with
plausible magnitudes for a z=0.6 galaxy group. However, the associated X-ray
emission does not imply sufficient mass to produce the observed image
splitting. The lens scenario thus requires a dark (high M/L ratio) lens, or a
fortuitous configuration of masses along the line of sight. UM425 may instead
be a close binary pair of BALQSOs, which would boost arguments that
interactions and mergers increase nuclear activity and outflows.Comment: 13 pages, 9 figures, Accepted for publication in the Astrophysical
Journa
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