441 research outputs found
Satisfacción laboral y ecoeficiencia en la Dirección Regional de Salud del Callao, 2017
El presente estudio tuvo por finalidad relacionar las variables satisfacción laboral y
ecoeficiencia, en la Dirección Regional de Salud del Callao; una investigación de tipo
básica, alcance descriptivo correlacional, no experimental de enfoque cuantitativo,
diseño transversal, y método hipotético deductivo. Se realizó mediante la técnica de
encuestas, -validadas internacionalmente y por el juicio de expertos- al personal
profesional que cumple labores administrativas de la Dirección Regional de Salud –
DIRESA Callao en el año 2017; la muestra consistió de 76 personas.
Los instrumentos utilizados presentaron una alta confiabilidad con un alfa de
Cronbach de 0,925 para el cuestionario de satisfacción laboral de Meliá y Peiró,
modificado por Chiang et al (2008), adaptado, que consta de 37 items, distribuidos en
seis dimensiones: trabajo en general, ambiente físico, trabajo en equipo,
reconocimiento, relación jefe subordinado y remuneración. El cuestionario de Marrou
y García (2014), para la ecoeficiencia, modificado por Hinostroza (2015), adaptado,
obtuvo una confiabilidad de 0,904, consta de 43 ítems y las dimensiones gestión de la
energía, capacitación y gestión de residuos sólidos.
Los resultados determinaron la inexistencia de correlación entre las variables
satisfacción laboral y ecoeficiencia (r= -0,046) y la significancia bilateral de 0,690, por
lo cual se aceptó la hipótesis nula, afirmándose que no existe relación entre las
variables estudiadas en la Dirección Regional de Salud–DIRESA Callao en el año
2017. Las correlaciones entre la satisfacción laboral y las dimensiones de la
ecoeficiencia mostraron resultados similares: gestión de la energía (r=0,029),
capacitación (r=-0,046) y gestión de residuos sólidos (r=-0,019), aceptándose la
hipótesis nula en cada caso
Abandoning ‘a Lifetime of Habits’ to Avoid the ‘Sins of the Past’: De-Congregating Institutions with Deeply Ingrained Traditions
While many studies have identified the problem of reproducing small institutions in community settings, few have explored why. This article explores how staff preserve and defend institutionalised beliefs and practices in community settings. We apply the concepts of disruptive and defensive institutional work to analyse the findings of qualitative interviews at six Irish residential institutions that were identified as priority sites for a national de-congregation programme. Reflecting on their roles, staff conceptualised their practices as historical, traditional, and reflective of a bygone era. However, the findings indicate that it would be misleading to represent institutional practices as relics of the past. The programme offered an olive branch for staff members who wanted to distance themselves from a ‘lifetime of habits’ and ‘sins of the past’
Family quality of life and the building of social connections: practical suggestions for practice and policy
Copyright (c) 2018 Meaghan Edwards, Trevor Parmenter, Patricia O'Brien, Roy Brown
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.Family quality of life literature suggests that families with a member with an intellectual/developmental disability frequently face major difficulties in building social connections with others. They experience low levels of social support, face challenges in community inclusion, and are at risk of social isolation. These challenges may also be faced by other types of marginalized families. Families experiencing serious illness, families experiencing intrafamily violence, and migrant families or those seeking political asylum, for example, may also become isolated and find themselves without pathways to connections with others. We present practical suggestions intended for families and professionals interested in action and intervention at the personal, community, program, and policy levels to encourage the growth of social connections and prevent isolation of families experiencing social exclusion. The suggestions will come from families with a member with a disability and the findings of a study examining the social support of families as it relates to quality of life
Evidence Collection for the Unconscious and Unconsented Patient
Forensic nurses are faced with making an ethical decision when an unconscious patient presents with signs of sexual assault. If the patient is unable to consent, the nurses need to decide whether or not to perform a forensic exam. Hospitals have policies in place regarding consent for emergency care, but not all of them consider the collection of forensic evidence. The window of opportunity for forensic collection may disappear before contacts are made or proper consent is established.\ud
Ethical, legal, and policy considerations that complicate this scenario are discussed
Swift Observations of GRB 050603: An afterglow with a steep late time decay slope
We report the results of Swift observations of the Gamma Ray Burst GRB
050603. With a V magnitude V=18.2 about 10 hours after the burst the optical
afterglow was the brightest so far detected by Swift and one of the brightest
optical afterglows ever seen. The Burst Alert Telescope (BAT) light curves show
three fast-rise-exponential-decay spikes with =12s and a fluence of
7.6 ergs cm in the 15-150 keV band. With an ergs it was also one of the most energetic
bursts of all times. The Swift spacecraft began observing of the afterglow with
the narrow-field instruments about 10 hours after the detection of the burst.
The burst was bright enough to be detected by the Swift UV/Optical telescope
(UVOT) for almost 3 days and by the X-ray Telescope (XRT) for a week after the
burst. The X-ray light curve shows a rapidly fading afterglow with a decay
index =1.76. The X-ray energy spectral index was
=0.71\plm0.10 with the column density in agreement with the
Galactic value. The spectral analysis does not show an obvious change in the
X-ray spectral slope over time. The optical UVOT light curve decays with a
slope of =1.8\plm0.2.
The steepness and the similarity of the optical and X-ray decay rates suggest
that the afterglow was observed after the jet break. We estimate a jet opening
angle of about 1-2Comment: 14 pages, accepted for publication in Ap
Contrasting origin of B chromosomes in two cervids (Siberian roe deer and grey brocket deer) unravelled by chromosome-specific DNA sequencing
Abstract
Background
B chromosomes are dispensable and variable karyotypic elements found in some species of animals, plants and fungi. They often originate from duplications and translocations of host genomic regions or result from hybridization. In most species, little is known about their DNA content. Here we perform high-throughput sequencing and analysis of B chromosomes of roe deer and brocket deer, the only representatives of Cetartiodactyla known to have B chromosomes.
Results
In this study we developed an approach to identify genomic regions present on chromosomes by high-throughput sequencing of DNA generated from flow-sorted chromosomes using degenerate-oligonucleotide-primed PCR. Application of this method on small cattle autosomes revealed a previously described KIT gene region translocation associated with colour sidedness. Implementing this approach to B chromosomes from two cervid species, Siberian roe deer (Capreolus pygargus) and grey brocket deer (Mazama gouazoubira), revealed dramatically different genetic content: roe deer B chromosomes consisted of two duplicated genomic regions (a total of 1.42-1.98 Mbp) involving three genes, while grey brocket deer B chromosomes contained 26 duplicated regions (a total of 8.28-9.31 Mbp) with 34 complete and 21 partial genes, including KIT and RET protooncogenes, previously found on supernumerary chromosomes in canids. Sequence variation analysis of roe deer B chromosomes revealed a high frequency of mutations and increased heterozygosity due to either amplification within B chromosomes or divergence between different Bs. In contrast, grey brocket deer B chromosomes were found to be more homogeneous and resembled autosomes in patterns of sequence variation. Similar tendencies were observed in repetitive DNA composition.
Conclusions
Our data demonstrate independent origins of B chromosomes in the grey brocket and roe deer. We hypothesize that the B chromosomes of these two cervid species represent different stages of B chromosome sequences evolution: probably nascent and similar to autosomal copies in brocket deer, highly derived in roe deer. Based on the presence of the same orthologous protooncogenes in canids and brocket deer Bs we argue that genomic regions involved in B chromosome formation are not random. In addition, our approach is also applicable to the characterization of other evolutionary and clinical rearrangements
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18 F-AV1451 PET imaging and multimodal MRI changes in progressive supranuclear palsy
Funder: PSP Association; doi: http://dx.doi.org/10.13039/100011707Abstract: Objectives: Progressive supranuclear palsy (PSP) is characterized by deposition of straight filament tau aggregates in the grey matter (GM) of deep nuclei and cerebellum. We examined the relationship between tau pathology (assessed via 18F-AV1451 PET) and multimodal MRI imaging using GM volume, cortical thickness (CTh), and diffusion tensor imaging (DTI). Methods: Twenty-three people with clinically probable PSP-Richardson’s syndrome (age 68.8 ± 5.8 years, 39% female) and 23 controls underwent structural 3 T brain MRI including DTI. Twenty-one patients also had 18F-AV1451 PET imaging. Voxelwise volume-based morphometry, surface-based morphometry, and DTI correlations were performed with 18F-AV1451 binding in typical PSP regions of interest (putamen, thalamus and dentate cerebellum). Clinical impairment was also assessed in relation to the different imaging modalities. Results: PSP subjects showed GM volume loss in frontotemporal regions, basal ganglia, midbrain, and cerebellum (FDR-corrected p < 0.05), reduced CTh in the left entorhinal and fusiform gyrus (p < 0.001) as well as DTI changes in the corpus callosum, internal capsule, and superior longitudinal fasciculus (FWE-corrected p < 0.05). In PSP, higher 18F-AV1451 binding correlated with GM volume loss in frontal regions, DTI changes in motor tracts, and cortical thinning in parietooccipital areas. Cognitive impairment was related to decreased GM volume in frontotemporal regions, thalamus and pallidum, as well as DTI alteration in corpus callosum and cingulum. Conclusion: This cross-sectional study demonstrates an association between in vivo proxy measures of tau pathology and grey and white matter degeneration in PSP. This adds to the present literature about the complex interplay between structural changes and protein deposition
Linking migration to community resilience in the receiving basin of a large-scale water transfer project
Large-scale water transfer projects (LWTPs) transfer water to urban and agricultural areas. The Majes-Siguas canal, established in 1983, is an LWTP that created a thriving agricultural area through irrigating the Majes district in the Atacama Desert of Peru. Like other LWTP receiving basins, the project has attracted an influx of migrants who work on the farms. At the same time, the Majes LWTP is the district’s only source of water and has an aging infrastructure which presents significant risks. While many studies critically analyze the consequences of LWTPs in water supply basins, few evaluate the resilience of communities living in LWTP receiving basins. In this study, we ask: what factors stifle or enable resilience of the agricultural community in the Majes-Siguas receiving basin? In 2019, we conducted semi-structured interviews with migrant and residents and water authorities, collected and reviewed historical documents, and conducted participant observations. Using this data, we analyze community resilience by identifying perceived risks, stressors, and vulnerabilities among and between groups of agricultural actors, their adaptations, and their perceptions of water management organizations’ responses. Results show that a single source of water, differential vulnerabilities between groups of agricultural actors, and limited organizational responsiveness stifled community resilience, while communal pooling and self-organization enabled community resilience. Attention to increasing inclusion of migrants in water management decision-making, addressing differential water and land rights, and cultivating space for migrant self-organization could enable the agricultural community to be more resilient
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