4 research outputs found
Evaluation of the cytotoxic and genotoxic potential of Khat (Catha edulis Forsk) extracts on human T lymphoblastoid cell line
This paper reports on an investigation of the cytotoxic and genotoxic potential of khat extract using a human T lymphoblastoid cell line (CEM). Exponentially growing CEM cells were cultured for 12 h in the presence of khat extract (0-2000 μg ml-1). Statistically significant, dose-dependent increases in; CEM cell death at dose (> 400 μg ml-1), in DNA damage at dose (>200 μg ml-1) and in micronuclei frequency, at dose (>200 μg ml-1) were observed. The genetic damage effects of khat extract on human cell line observed in this study could serve as a major contribution towards the understanding and creating of awareness of an increased risk of cancer amongst long-term khat consumers
Additional file 1: of Dexmedetomidine and intravenous acetaminophen for the prevention of postoperative delirium following cardiac surgery (DEXACET trial): protocol for a prospective randomized controlled trial
Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) checklist. The document represents the SPIRIT Checklist. (DOC 135 kb
Additional file 1: of Intraoperative oxygen concentration and neurocognition after cardiac surgery: study protocol for a randomized controlled trial
Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) checklist. The document represents the SPIRIT Checklist. (DOC 121 kb