Invariance Violation Extends the Cosmic Ray Horizon ?

We postulate in the present paper that the energy-momentum relation is modified for very high energy particles to violate Lorentz invariance and the speed of photon is changed from the light velocity c. The violation effect is amplified, in a sensitive way to detection, through the modified kinematical constraints on the conservation of energy and momentum, in the absorption process of gamma-rays colliding against photons of longer wavelengths and converting into an electron-positron pair. For gamma-rays of energies higher than 10 TeV, the minimum energy of the soft photons for the reaction and then the absorption mean free path of gamma-rays are altered by orders of magnitude from the ones conventionally estimated. Consideration is similarly applied to high energy cosmic ray protons. The consequences may require the standard assumptions on the maximum distance that very high energy radiation can travel from to be revised.Comment: 14 pages, 1 figure, to be published in Ap J Letter

Preregistration house officers in general practice: review of evidence

OBJECTIVES: To examine the strengths and weaknesses of the national and local schemes for preregistration house officers to spend four months in general practice, to identify any added value from such placements, and to examine the impact on career choices. DESIGN: Review of all studies that reported on placements of preregistration house officers in general practice. SETTING: 19 accounts of preregistration house officers’ experience in general practice, ranging from single case reports to a national evaluation study, in a variety of locations in Scotland and England. PARTICIPANTS: Views of 180 preregistration house officers, 45 general practitioner trainers, and 105 consultant trainers. MAIN OUTCOME MEASURES: Main findings or themes weighted according to number of studies reporting them and weighted for sample size. RESULTS: The studies were unanimous about the educational benefits of the placements. The additional learning included communication skills, social and psychological factors in illness, patient centred consultations, broadening of knowledge base, and dealing with uncertainty about diagnosis and referral. CONCLUSIONS: Despite the reported benefits and recommendations of the scheme, it is not expanding. General practitioner trainers reported additional supervision that was unremunerated. The reforms of the senior house officer grade may resolve this problem by offering the placements to senior house officers, who require less supervision

The Discovery of an Active Galactic Nucleus in the Late-type Galaxy NGC 3621: Spitzer Spectroscopic Observations

We report the discovery of an Active Galactic Nucleus (AGN) in the nearby SAd galaxy NGC 3621 using Spitzer high spectral resolution observations. These observations reveal the presence of [NeV] 14 um and 24 um emission which is centrally concentrated and peaks at the position of the near-infrared nucleus. Using the [NeV] line luminosity, we estimate that the nuclear bolometric luminosity of the AGN is ~ 5 X 10^41 ergs s^-1, which corresponds based on the Eddington limit to a lower mass limit of the black hole of ~ 4 X 10^3 Msun. Using an order of magnitude estimate for the bulge mass based on the Hubble type of the galaxy, we find that this lower mass limit does not put a strain on the well-known relationship between the black hole mass and the host galaxy's stellar velocity dispersion established in predominantly early-type galaxies. Mutli-wavelength follow-up observations of NGC 3621 are required to obtain more precise estimates of the bulge mass, black hole mass, accretion rate, and nuclear bolometric luminosity. The discovery reported here adds to the growing evidence that a black hole can form and grow in a galaxy with no or minimal bulge.Comment: 5 pages, 7 figures, Accepted for publication in ApJ Letter

Membrane Adhesion and the Formation of Heterogeneities: Biology, Biophysics, and Biotechnology

a. The University of Texas at Austin, Department of Physics and Center for Nonlinear Dynamics, 2515 Speedway, Stop C1610, Austin, Texas 78712-1199, USA. E-mail: [email protected] b.The University of Texas at Austin, Department of Molecular Biosciences, Institute for Cellular and Molecular Biology, Austin, Texas 78712-1199, USAMembrane adhesion is essential to many vital biological processes. Sites of membrane adhesion are often associated with heterogeneities in the lipid and protein composition of the membrane. These heterogeneities are thought to play functional roles by facilitating interactions between proteins. However, the causal links between membrane adhesion and membrane heterogeneities are not known. Here we survey the state of the field and indicate what we think are understudied areas ripe for development.This work is supported by startup funds from UT Austin and a gift from ExxonMobile to VDG and by NIH R01 R01 GM089896 to T.J.O.Center for Nonlinear Dynamic

The response of ground-dwelling spiders (Araneae) and hoverflies (Diptera: Syrphidae) to afforestation assessed using within site tracking

In many countries throughout the world, the area of plantation forests continues to increase and they now dominate many landscapes. In recent decades, forest cover in Ireland has expanded largely due to commercial afforestation with non-native conifers. This study provides the first within-site assessment of the response of two important arthropod groups to afforestation in agricultural grasslands in Ireland. Five sites were studied 1 year before and 7 years after afforestation using pitfall trapping for active ground-dwelling spiders and Malaise trapping for hoverflies. Both species groups were studied in grassland habitat, and spiders were also sampled in field boundary hedgerow habitat. Afforestation within the study sites had a positive effect on ground-dwelling spider diversity over the first 7 years; total species richness increased in afforested grassland and hedgerow habitats, and forest specialist species richness increased in afforested grassland habitat. This was concurrent with, and most likely influenced by, the increase in habitat structure created by the forest vegetation, litter and deadwood layers and the increase in canopy cover. There was no effect of afforestation on hoverfly species richness over the first 7 years, possibly due to confounding effects of hoverfly movements across landscapes. Spider and hoverfly species compositions were also positively affected by afforestation. These results indicated that afforestation in our study sites, set within a predominantly agricultural landscape, benefitted arthropod diversity by increasing habitat diversity. Hedgerow habitats were also an important contributor to biodiversity in these newly planted forests. Ecologically oriented planning and management of afforestation must consider the influence of habitat quality in forest plantations, including the protection of biodiversity rich habitats and the quality of the land being afforested, to improve the contribution to biodiversity enhancement and conservation

Established cardiovascular disease and CVD risk factors in a primary care population of middle-aged Irish men and women

Contemporary Irish data on the prevalence of major cardiovascular disease (CVD) risk factors are sparse. The primary aims of this study were (1) to estimate the prevalence of major cardiovascular disease risk factors, including Type 2 Diabetes Mellitus, in the general population of men and women between the ages of 50 and 69 years; and (2) to estimate the proportion of individuals in this age group at high absolute risk of cardiovascular disease events on the basis of pre-existing cardiovascular disease or as defined by the Framingham equation. Participants were drawn from the practice lists of 17 general practices in Cork and Kerry using stratified random sampling. A total of 1018 people attended for screening (490 men, 48%) from 1473 who were invited, a response rate of 69.1%. Cardiovascular disease risk factors and glucose intolerance are common in the population of men and women aged between 50 and 69 years. Almost half the participants were overweight and a further quarter met current international criteria for obesity, one of the highest recorded prevalence rates for obesity in a European population sample. Forty per cent of the population reported minimal levels of physical activity and 19% were current cigarette smokers. Approximately half the sample had blood pressure readings consistent with international criteria for the diagnosis of hypertension, but only 38% of these individuals were known to be hypertensive. Eighty per cent of the population sample had a cholesterol concentration in excess of 5 mmol/l. Almost 4% of the population had Type 2 Diabetes Mellitus, of whom 30% were previously undiagnosed. A total of 137 participants (13.5%) had a history or ECG findings consistent with established cardiovascular disease. Of the remaining 881 individuals in the primary prevention population, a total of 20 high-risk individuals (19 male) had a risk of a coronary heart disease event 30% over ten years according to the Framingham risk equation, giving an overall population prevalence of 2.0% (95% CI 1.3 - 3.0). At a risk level 20% over ten years, an additional 91 individuals (8.9%) were identified. Thus a total of 24.4% of the population were at risk either through pre-existing CVD (13.5%) or an estimated 10-year risk exceeding 20% according to the Framingham risk equation (10.9%). Thus a substantial proportion of middle-aged men are at high risk of CVD. The findings emphasise the scale of the CVD epidemic in Ireland and the need for ongoing monitoring of risk factors at the population level and the need to develop preventive strategies at both the clinical and societal level

Summertime Influences of Tidal Energy Advection on the Surface Energy Balance in a Mangrove Forest

Mangrove forests are ecosystems susceptible to changing water levels and temperatures due to climate change as well as perturbations resulting from tropical storms. Numerical models can be used to project mangrove forest responses to regional and global environmental changes, and the reliability of these models depends on surface energy balance closure. However, for tidal ecosystems, the surface energy balance is complex because the energy transport associated with tidal activity remains poorly understood. This study aimed to quantify impacts of tidal flows on energy dynamics within a mangrove ecosystem. To address the research objective, an intensive 10-day study was conducted in a mangrove forest located along the Shark River in the Everglades National Park, FL, USA. Forest–atmosphere turbulent exchanges of energy were quantified with an eddy covariance system installed on a 30-m-tall flux tower. Energy transport associated with tidal activity was calculated based on a coupled mass and energy balance approach. The mass balance included tidal flows and accumulation of water on the forest floor. The energy balance included temporal changes in enthalpy, resulting from tidal flows and temperature changes in the water column. By serving as a net sink or a source of available energy, flood waters reduced the impact of high radiational loads on the mangrove forest. Also, the regression slope of available energy versus sink terms increased from 0.730 to 0.754 and from 0.798 to 0.857, including total enthalpy change in the water column in the surface energy balance for 30-min periods and daily daytime sums, respectively. Results indicated that tidal inundation provides an important mechanism for heat removal and that tidal exchange should be considered in surface energy budgets of coastal ecosystems. Results also demonstrated the importance of including tidal energy advection in mangrove biophysical models that are used for predicting ecosystem response to changing climate and regional freshwater management practices