Embedded earrings as a result of misuse: Case report

Earrings-related complications are mostly caused by piercing. To our knowledge, there is no report regarding embedded earrings without the effect of piercing in the English-language literature. In this report, we describe two cases of embedding of earring pins while wearing but not having resulted from piercing

Case Report - Embedded earrings as a result of misuse: Case report

Earrings-related complications are mostly caused by piercing. To our knowledge, there is no report regarding embedded earrings without the effect of piercing in the English-language literature. In this report, we describe two cases of embedding of earring pins while wearing but not having resulted from piercing

Nevus Sebaceous and Accompanying Lesions: A Clinicopathologic Review of Seven Patients

Purpose: Benign lesions are frequently develops in nevus sebaceous, while malignancies mayalso be seen rarely. We aimed to review the pathologies developed from nevus sebaceous in ourpatients. Material and method: Seven patients with nevus sebaceous, whose diagnoses andmanagements had been carried out in our department during the last six years, were reviewed.Diagnoses were verified by the examination of a pathologist. Results: In addition to the seven sebaceous nevi that were five in the scalp and two in the cheek,syringocystadenoma papilliferum in a patient, eccrine spiroadenoma in one patient, and bothsyringocystadenoma papilliferum and tubular apocrine adenoma in a patient were seen. Totalsurgical excision was performed for all patients. No recurrence was noticed in any of the tumorsin the follow-up. Conclusion: Prophylactic excision has been suggested because of the probable neoplastictransformations in elderly. In our series, early excision had been performed in almost all patientsand no malignant transformation was detected. Concerning the neoplastic changes are seenusually at the ages of 40-70 and aesthetically disturbing lesions rise in adolescent period, wesuggest that excision can be delayed to adolescent period

Expression of Connexin 32 and Connexin 43 gap junction proteins in basal and squamous cell carcinomas

Gap junctions play a role in intercellular communication in the epithelium, muscle and nerve tissues, and many more tissues and organs. These linking regions and the proteins forming them are called connexins (Cx). Recent studies show that cellular homeostatic equilibrium can be influenced by connexins. In this study, the expression of Cx43 and Cx32 in basal cell carcinoma (BCC) and squamous cell carcinomas (SCC) is tried studied. A total of 45 cases, 23 male and 22 female, were included in the study. Twenty of the cases were SCC and twenty-five were BCC. Retrospective data from records were examined and specimens were investigated by immunohistochemistry staining. It was determined that the results of Cx 43 and Cx 32 staining changed according to the tumor type of cases (P = 0,020). It was determined that the results of Cx43 and Cx32 staining did not change according to the sex and age, BCC and SCC subtype, and location. Losses of Cx43 and Cx32 have been shown to be associated with tumor types. We believe that it can be used as a support marker of SCC and BCC differential diagnosis. [Med-Science 2023; 12(1.000): 192-6

Histological assessment of skin grafts stored in amniotic fluid and saline

We investigated the efficacy of amniotic fluid as a substance in which to store grafts; it is rich in nutrients, proteins, and growth factors, and has well-known antimicrobial features. We compared it with the widely-used and practical saline. Split-thickness grafts 4 x 4 cm were prepared from the back of 20 rats and divided into four groups (n = 5 each). The rolled grafts were wrapped in gauze dampened with saline or amniotic fluid and placed into refrigerators in sterile containers for storage. On days 7, 14, 21, and 28, histological examinations were made. A semiquantitative evaluation of the histological damage to the skin was made by scoring its degree of severity. Compared with saline, histological scores in the grafts stored in amniotic fluid were found to be significantly lower on the 14th, 21st, and 28th days (p values on days 14, 21, and 28; cell swelling: 0.014, 0.006, and 0.005, respectively; nuclear swelling: 0.003, 0.006, and 0.007, respectively; nuclear pleomorphism: 0.004, 0.005, and 0.003, respectively; nuclear haloes: 0.015, 0.005, and 0.005, respectively; nuclear pyknosis: 0.003, 0.005, and 0.003, respectively; dermo-epidermal clefting: 0.005, 0.003, and 0.003, respectively; eosinophilia and mitosis: 0.003, 0.006, and 0.004, respectively; dermal collagen: 0.003, 0.003, and 0.003, respectively). Amniotic fluid maintained preservation better for skin grafts than saline. Comparison with other modern storage media would be beneficial

Prevalence Of Temporomandibular Disorders In Pregnancy

Aim : To determine if the prevalence of systemic joint hypermobil-ity and temporomandibular disorders (TMD) is higher during preg-nancy or not and also to confirm a correlation between systemic joint hypermobility and TMD. Methods : 70 pregnant and 40 age-matched non pregnant women were enrolled in the study. 30% of the pregnant women were in the first trimester of gestation, 34.3% of them were in the second,and 35.7% of them were in the third trimester. All of the sub-jects completed a self-administered questionnaire, and underwent a standardized clinical examination using the Research Diagnostic Criteria for TMD (RDC/TMD). Hypermobility was determined ac-cording to the criteria of Beighton et al. Results : 7.1% of the pregnant women and 7.5% of the non-preg-nant women received an RDC/TMD Axis I diagnosis (p> 0.05). 31.4% of the pregnant women and 40% of the non-pregnant women had systemic joint hypermobility (p> 0.05). Among all subjects who received a RDC/TMD Axis I diagnosis, 35.3% had systemic joint hypermobility and among all subjects who did not meet criteria to receive a RDC/TMD Axis I diagnosis, 25% had systemic joint hypermobility (p> 0.05). Conclusion : The prevalence of TMD and systemic joint hypermo-bility were not high among pregnant women compared to age matched non-pregnant women. And we were not able to confirm a correlation between systemic joint hypermobility and TMD

Presence of Interferon Regulatory Factor-1 in Aggressive and Nonaggressive Histological Variants of Basal Cell Carcinoma Specimens

Background : Expression of Interferon regulatory factor-1 (IRF-1) has been demonstrated in a variety of cancers previously. To the best of our knowledge, there is only one report about the IRF-1 expression in basal cell carcinoma (BCC) specimens, which has demonstrated increased expression of the IRF-1 gene in BCC versus normal skin. Furthermore, IRF-1 expression has not been compared between aggressive and nonaggressive subtypes of BCC before. Aims : Our aim is to examine the relation between IRF-1 staining patterns of aggressive and nonaggressive histological subtypes of BCC. Materials and Methods : Thirty-seven archival tissue specimens from 33 BCC patients were stained for cytoplasmic and nuclear IRF-1. Twenty-five tumors were grouped as nonaggressive and 12 were grouped as aggressive histological variants, according to the established criteria. Results : IRF-1 was not only expressed in tumor cells, but also in some surrounding inflammatory cells. There was no significant difference between the groups for cytoplasmic or nuclear IRF-1 staining. Aggressive or nonaggressive histological subtypes did not show any statistical difference for gender, relapse, treatment method, or localization. When staining was compared with gender, relapse, treatment method, localization, and tumor grades, no significant difference was found. Conclusions : Interferon seems to be expressed in BCCs with both aggressive and non aggressive histology. Further studies are needed to elaborate the precise diagnostic and prognostic roles and utility of interferon in the treatment of BCC