Epidemiology and biology of cutaneous human papillomavirus

Cutaneous human papillomaviruses (HPVs) include b- and g-HPVs, in addition to a small fraction of a-HPVs. b-HPVs were first isolated from patients with the rare genetic disorder Epidermodysplasia verruciformis, and they are associated with the development of nonmelanoma skin cancer at sun-exposed skin sites in these individuals. Organ transplant recipients also have greater susceptibility to b-HPV infection of the skin and an increased risk of developing nonmelanoma skin cancer. In both immunosuppressed and immunocompromised individuals, cutaneous HPVs are ubiquitously disseminated throughout healthy skin and may be an intrinsic part of the commensal flora. Functional analysis of E6 and E7 proteins of specific cutaneous HPVs has provided a mechanistic comprehension of how these viruses may induce carcinogenesis. Nevertheless, additional research is crucial to better understand the pathological implications of the broad distribution of these HPVs

School diagnostic: Perceptions of educational professionals

Aim: The school is a privileged context to prevent certain problems that may begin during the development of young students. The main objective is to assess the perceptions of educational professionals about the school structure, functioning, and organization, as well as students’ behaviors. Method: We developed an exploratory study using a questionnaire, applied to a sample of 81 educational agents, teachers and non-teachers, aged between 25 and 62 years (M = 45.8, SD = 10.6). Results: Despite the positive perception of the participants about the physical school environment, it is necessary to create spaces for leisure and sport, logistic conditions and multidisciplinary teams in order to maximize the overall good functioning of schools. Adding to this, participants described the participation of parents in the school life as negative; they also identified several disruptive behaviours among students and referred to a general lack of active participation in life school. Conclusion: It is important to create action plans in schools, which should be multimodal and multi-agent in order to have intervention perspectives with connected actions developed by different educational agents.info:eu-repo/semantics/publishedVersio

Café: consumo regular, dependência e consequências para a saúde

A cafeína é uma substância que integra a composição de produtos consumidos em todo o mundo, nomeadamente, o café. Entre as consequências desse consumo, contam-se os malefícios e a sua acção sobre o Sistema Nervoso Central. Após apresentar uma breve história do café, este artigo procura expor a multiplicidade de efeitos nefastos da sua ingestão. No entanto, salienta-se também o papel do café que, enquanto bebida e enquanto espaço de convívio, facilita a comunicação e promove a interacção. Caffeine is a psychoactive substance, which takes part in the composition of a large diversity of regularly consumed products all over the world, especially coffee. Coffee consumption has several harmful consequences at various levels, with baneful effects on the Central Nervous System. After presenting a brief history of coffee, this article tries to expose the multiplicity of its harmful effects. We also present coffee as a drink and as a space (coffee-house) which promotes communication and interaction

Drug abuse and trafficking in universities: an emerging social phenomenon

According to Nova’s Policy for Self-Archiving, self-archiving of proofed chapters can be posted on the author’s website free of charge six months after publication. For Subject and Institutional Repositories, proofed chapters can be uploaded 12 months after publication. For more information, please see: https://novapublishers.com/open-access/Higher education is the environment in which the future senior managers that will guide the forthcoming of societies are wrought. Therefore, and in social terms, everything that people learn and develop in these higher education institutions has a crucial and a determinant impact. Young people acquiring skills and knowledge related to the technical and scientific fields in which they work in also end up acquiring competencies and knowledge in non-academic fields, such as anti-social behaviour or even criminal conducts. This is the case of drug use in a university context, which has been so studied in recent decades, and of drug trafficking in a university environment, widely known to all, but still little investigated in scientific terms. Therefore, and taking into consideration that universities play a social role that has a strong impact on the lives of young people and societies, this chapter is precisely dedicated to the phenomena of drug trafficking, and its use/abuse in universities. It is a serious social problem in which young students not only consume illegal drugs, but also frequently take an active part in illicit activities associated with drug trafficking, often compromising their future and causing undeniable social damage. It should be noted that the university context is a privileged target for the powerful individuals who manipulate these illegal drugs markets. It is therefore very important to pay attention and study this social problem of serious consequences. In this chapter, a comprehensive literature review and results of a study about drug trafficking and abuse in university context will be presented, in order to better understand the nature of this problem. Final considerations regarding the prevention/intervention on these phenomena are also presented.info:eu-repo/semantics/publishedVersio

Drug Abuse and Trafficking in Universities: An Emerging Social Phenomenon

According to Nova’s Policy for Self-Archiving, self-archiving of proofed chapters can be posted on the author’s website free of charge six months after publication. For Subject and Institutional Repositories, proofed chapters can be uploaded 12 months after publication. For more information, please see: https://novapublishers.com/open-access/Higher education is the environment in which the future senior managers that will guide the forthcoming of societies are wrought. Therefore, and in social terms, everything that people learn and develop in these higher education institutions has a crucial and a determinant impact. Young people acquiring skills and knowledge related to the technical and scientific fields in which they work in also end up acquiring competencies and knowledge in non-academic fields, such as anti-social behaviour or even criminal conducts. This is the case of drug use in a university context, which has been so studied in recent decades, and of drug trafficking in a university environment, widely known to all, but still little investigated in scientific terms. Therefore, and taking into consideration that universities play a social role that has a strong impact on the lives of young people and societies, this chapter is precisely dedicated to the phenomena of drug trafficking, and its use/abuse in universities. It is a serious social problem in which young students not only consume illegal drugs, but also frequently take an active part in illicit activities associated with drug trafficking, often compromising their future and causing undeniable social damage. It should be noted that the university context is a privileged target for the powerful individuals who manipulate these illegal drugs markets. It is therefore very important to pay attention and study this social problem of serious consequences. In this chapter, a comprehensive literature review and results of a study about drug trafficking and abuse in university context will be presented, in order to better understand the nature of this problem. Final considerations regarding the prevention/intervention on these phenomena are also presented.info:eu-repo/semantics/publishedVersio

Campus Criminal Victimization among Higher Education Students: A Diagnosis of Local Security in Porto

This study addressed and characterized direct and indirect criminal victimization among college students and examined the associations between victimization and other variables. The participants were 775 students of both genders with a mean age of 21.76 years. Data were collected through self-reports using the “Diagnosis of Local Security Questionnaire”. Overall, 8.6% of the students reported direct victimization, and 39.7% reported indirect victimization. The most reported crimes were robbery and theft, while the least prevalent were sexual offense, domestic violence, and fraud. Most incidents involved a stranger and occurred at night in the street. Direct victimization was associated with gender, age, marital status, student level, attendance status, and institution domain. There were significant associations between indirect victimization and nationality, student type, attendance status, and institution domain. The perception of (in)security was significantly associated with victimization. Therefore, physical and social measures are necessary to reduce crime and increase security.FCT (Foundation for Science and Technology)info:eu-repo/semantics/publishedVersio

Do you feel safe in the urban space? From perceptions to associated variables

This study aims to provide answers to the following questions: Do you feel safe at Historic Centre of Porto (HCP)? Do you think that crime is increasing? What are the most and less frequent crimes? And the most feared crimes? What conditions promote criminal occurrences? What incivilities occur at HCP? What measures can be taken to increase security? What variables are related to the perception of insecurity? Through the application of the Diagnosis of Local Security Questionnaire, 554 participants that attended HCP were assessed (58.5% women, mean age = 43.82). One in five participants reported feelings of insecurity due to the presence of crime/danger. Robbery, theft, and drugs traffic were perceived as the most common crimes; participants were especially fearful about robbery and theft. Nationality, education, criminal variables, adequacy and satisfaction with policing, seek for formal support, and years living/studying/working at HCP were variables related to perception of (in)security.Este estudio tiene como objetivo proporcionar respuesta a las siguientes preguntas: ¿se siente seguro en el Centro Histórico de Oporto (CHO)?, ¿cree que la delincuencia está aumentando?, ¿cuáles son los delitos más y menos frecuentes?, ¿y los crímenes más temidos?, ¿qué condiciones fomentan los actos delictivos?, ¿qué faltas de civismo ocurren en el CHO?, ¿qué medidas se podrían tomar para aumentar la seguridad?, ¿qué variables están relacionadas con la percepción de inseguridad? Mediante la aplicación del Cuestionario de Diagnóstico de Seguridad Local se evaluó a 554 participantes que asistieron al CHO (58.5% mujeres, edad media 43.82). Uno de cada cinco participantes manifestó sensación de inseguridad debido a la presencia de delitos/peligro. El robo, el hurto y el tráfico de drogas se percibían como los delitos más comunes; los participantes temían principalmente el robo y el hurto. La nacionalidad, la educación, las variables penales, la adecuación y la satisfacción con el trabajo policial, la búsqueda de apoyo formal y los años de vida/estudio/trabajo en el CHO fueron variables relacionadas con la percepción de (in)seguridad.info:eu-repo/semantics/publishedVersio

Violence against the elderly: narrative of a case

info:eu-repo/semantics/publishedVersio

Análise biográfica de indivíduos com história de consumo de substâncias

O estudo, exploratório e descritivo, visou a busca de uma eventual constância nos trajectos existenciais de indivíduos toxicodependentes. A amostra, homogénea, constou de 10 participantes com história de abuso de substâncias, portadores do vírus de imunodeficiência humana em fase de síndroma de imunodeficiência adquirida sujeitos a tratamento antiretrovírico e à administração de metadona. Verificou-se a presença de características comuns, nomeadamente em termos afectivos, de pobreza de imaginário e de participação em actos de delito, entre outras similaridades

Análise biográfica de indivíduos com história de consumo de substâncias

O estudo, exploratório e descritivo, visou a busca de uma eventual constância nos trajectos existenciais de indivíduos toxicodependentes. A amostra, homogénea, constou de 10 participantes com história de abuso de substâncias, portadores do vírus de imunodeficiência humana em fase de síndroma de imunodeficiência adquirida sujeitos a tratamento antiretrovírico e à administração de metadona. Verificou-se a presença de características comuns, nomeadamente em termos afectivos, de pobreza de imaginário e de participação em actos de delito, entre outras similaridades.The study, exploratory and descriptive, has as an aim the search of occasional stability in the course of individuals with drug addiction. The homogeneous sample consists in 10 participants with substance abuse history, porters of human immunodeficiency virus in phase of acquired immunodeficiency syndrome submitted to antiretroviruses treatment and to methadone administration. It was verified that the individuals reveal common characteristcs, namely, showed a poor speech of imaginary, a relation style lacking of affections, and have actively participated in crime activities.info:eu-repo/semantics/publishedVersio