Spatial productivity spillovers across Spanish municipalities

Whilst a great deal of e¤ort has been dedicated to identification of agglomeration effects on labour productivity, the measurement of spatial productivity spillovers is a question that has been addressed only occasionally along the New Economic Geography literature. We estimate agglomeration effects, nonetheless conditioned to the possible existence of spatial productivity spillovers across Spanish municipalities in year 2001. To this respect, we find that agglomeration effects are in the same order of magnitude than thoseencountered when measured in the standard way. Further, these agglomeration efects coexist with very strong spatial productivity spillovers in a close neighbourhood of 10 km. Finally, these spatial e¤ects are shown to quickly diminish as distance increases.IV estimation, elevation, spatial externalities, productivity, neighbourhood, Spain

The European Map of Job Flows

The European Map of Job Flows (EMJF) is a term used to denote a dataset of meso- and macro-level variables describing different aspect of labour mobility within national labour markets in Europe. In this paper, EMJF is centred on the notion of job “flows”, namely the changes in the level of employment at different breakdowns and levels of aggregation. EMJF is very rich in information content due to the wide variety of possible breakdown of the data and in this sense it is a “map” mostly in the virtual sense, namely, that it is not possible to visualise in the form of geographic maps all the wealth of available information. In terms of its value as a research product and tool, EMJF is mostly an intermediate product in the sense that it is a convenient means to organise the relevant information, which could subsequently be used for different analytical and research purposes. It provides both for cross-sections/snapshots of job flows at different point in time but also it allows their assessment and analysis over longer periods of time. In this sense, EMJF can be widely used for various types of labour-market analysis and research. EMJF’s visual components can also be a convenient tool for policy makers dealing with labour market policies at different level (regional, national or supra-national) in the decision-making process. Here we present a Compilation of a EMJF on the basis of firm-level data In this sense the job flows are built up on the basis of firm-level data for individual countries, following a common methodology. We adopt an approach of establishing such a EMJF on the basis of the AMADEUS dataset developed by the consultancy Bureau van Dijk. The dataset in its most extended version contains balance sheet data and ownership data for almost 14 million firms from 43 different European countries (September 2009 update). For many EU countries the dataset has in principle access to the entire universe of firms which have to report a balance sheet. In terms of countries, the geographic coverage of AMADEUS encompasses information for all the 27 members of the European Union (albeit with different qualities in terms of national coverage) as well as other 16 European countries that complete the geographical and political definition of the continent. Another interesting feature of the database is given by the detailed definition of a firm's location, with data available on the region (NUTS2) and the city in which the firm operates. This project deliverable presents the main results from the final stage of MICRO-DYN work on the EMJF. It discusses the approach to building the EMJF on the basis of AMADEUS data and illustrates the analytical potential of the EMJF as a research tool with a range of Europe-wide analytical exercises. Probably the most important outcome of this research effort is the demonstrated capability to perform meta-analysis at the European level of important labour market characteristics on the basis of firm-level data.job flows, europe, labor market, microdata

Diseño e implementación de divisor de frecuencia e integración del SoC CDR adaptativo a jitter con LFSR para pruebas y PLL interno con tecnología bicmos de 130 nm

Los lazos de seguimiento de fase se encuentran en una amplia gama de aplicaciones tales como los sistemas de comunicaciones inalámbricas, circuitos digitales y electrónica de discos duros, generando señales de fase amarrada con señales de entrada externas. Los lazos de seguimiento de fase están compuestos de un detector de frecuencia de fase, una bomba de carga, un filtro de lazo, un oscilador controlado por voltaje y un divisor de frecuencia en la ruta de realimentación. En este trabajo se presenta el diseño y la implementación física en tecnología BiCMOS8HP con proceso de litografía de 130 nm de un divisor de alta frecuencia para la retroalimentación de lazo de seguimiento de fase. Este diseño está compuesto por divisores asíncronos y diversos multiplexores para la selección de frecuencias externas o internas. El flujo de diseño de circuitos integrados para aplicaciones específicas implementado en este trabajo se describe paso a paso con detalle para que el trabajo pueda replicarse por cualquier persona interesada. Durante el flujo se presentan las herramientas y archivos utilizados en cada uno de los pasos. Además del diseño, las simulaciones aplicadas en cada una de las etapas del diseño se describen a detalle mostrando el código de la cama de pruebas y las formas de onda de los resultados obtenidos. Al final se muestra el diseño físico realizado y las verificaciones realizadas previas a la generación de los archivos para su exportación

Regulation of Ace2-dependent genes requires components of the PBF complex in schizosaccharomyces pombe

The division cycle of unicellular yeasts is completed with the activation of a cell separation program that results in the dissolution of the septum assembled during cytokinesis between the 2 daughter cells, allowing them to become independent entities. Expression of the eng1+ and agn1+ genes, encoding the hydrolytic enzymes responsible for septum degradation, is activated at the end of each cell cycle by the transcription factor Ace2. Periodic ace2+ expression is regulated by the transcriptional complex PBF (PCB Binding Factor), composed of the forkhead-like proteins Sep1 and Fkh2 and the MADS box-like protein Mbx1. In this report, we show that Ace2-dependent genes contain several combinations of motifs for Ace2 and PBF binding in their promoters. Thus, Ace2, Fkh2 and Sep1 were found to bind in vivo to the eng1+ promoter. Ace2 binding was coincident with maximum level of eng1+ expression, whereas Fkh2 binding was maximal when mRNA levels were low, supporting the notion that they play opposing roles. In addition, we found that the expression of eng1+ and agn1+ was differentially affected by mutations in PBF components. Interestingly, agn1+ was a major target of Mbx1, since its ectopic expression resulted in the suppression of Mbx1 deletion phenotypes. Our results reveal a complex regulation system through which the transcription factors Ace2, Fkh2, Sep1 and Mbx1 in combination control the expression of the genes involved in separation at the end of the cell division cycle

Phosphodiesterase isoforms and cAMP compartments in the development of new therapies for obstructive pulmonary diseases

The second messenger molecule 3′5′-cyclic adenosine monophosphate (cAMP) imparts several beneficial effects in lung diseases such as asthma, chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). While cAMP is bronchodilatory in asthma and COPD, it also displays anti-fibrotic properties that limit fibrosis. Phosphodiesterases (PDEs) metabolize cAMP and thus regulate cAMP signaling. While some existing therapies inhibit PDEs, there are only broad family specific inhibitors. The understanding of cAMP signaling compartments, some centered around lipid rafts/caveolae, has led to interest in defining how specific PDE isoforms maintain these signaling microdomains. The possible altered expression of PDEs, and thus abnormal cAMP signaling, in obstructive lung diseases has been poorly explored. We propose that inhibition of specific PDE isoforms can improve therapy of obstructive lung diseases by amplifying specific cAMP signals in discreet microdomains

A Milestone-Driven Approach for Lab Assignments Evaluation in Information Security

In this paper we describe a methodology for designing and evaluating lab assignments based on the fulfilment of milestones. The approach relies on the integration of ICTs with an automatic, milestone-based evaluation. The final goal of this methodology is to diminish educators’ workload on lab assignments, so they can focus on the development of the assigned tasks, and to enhance students’ experience by providing direct and real-time feedback on their progress. This approach encourages autonomous learning on the students and optimizes the time invested by the educators during the lab assignments. In order to validate our proposal we have applied this methodology in several courses related to Information Security. The results of this experience show that the methodology improves students’ performance, while facilitating the work of the educator.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Does hotel management matter to overcoming the COVID-19 crisis? The Spanish case

This paper analyses the influence that the initial actions and strategies pursued by hotel managers have on the recovery of occupancy after a crisis such as the COVID-19 pandemic. To do this, a specific survey is carried out on managers of Spanish hotels. The main findings show that labour actions, especially plans for temporary employment regulations, innovation and differentiation strategies, reorientation to closer markets and obtaining information from official sources as a guarantee of their certainty, are the measures that have a greater impact on the possibilities of recovering hotel activity. In addition, government measures that contribute to the improvement of the financial situation of firms can also play a relevant role in hotel recoveryThis research was supported by the Spanish Ministry of Science and Innovation (Research Project ECO2017-82445-R). We appreciate the comments of three anonymous reviewers who have significantly improved the articl

Gravitational fields as generalized string models

We show that Einstein's main equations for stationary axisymmetric fields in vacuum are equivalent to the motion equations for bosonic strings moving on a special nonflat background. This new representation is based on the analysis of generalized harmonic maps in which the metric of the target space explicitly depends on the parametrization of the base space. It is shown that this representation is valid for any gravitational field which possesses two commuting Killing vector fields. We introduce the concept of dimensional extension which allows us to consider this type of gravitational fields as strings embedded in D-dimensional nonflat backgrounds, even in the limiting case where the Killing vector fields are hypersurface orthogonal.Comment: latex, 25 page

Conceptual design of offshore platform supply vessel based on hybrid diesel generator-fuel cell power plant

Nowadays increasing fuel prices and upcoming pollutant emission regulations are becoming a growing concern for the shipping industry worldwide. While fuel prices will keep rising in future years, the new International Convention for the Prevention of Pollution from Ships (MARPOL) and Sulphur Emissions Control Areas (SECA) regulations will forbid ships to use heavy fuel oils at certain situations. To fulfil with these regulations, the next step in the marine shipping business will comprise the use of cleaner fuels on board as well as developing new propulsion concept. In this work a new conceptual marine propulsion system is developed, based on the integration of diesel generators with fuel cells in a 2850 metric tonne of deadweight platform supply vessel. The efficiency of the two 250 kW methanol-fed Solid Oxide Fuel Cell (SOFC) system installed on board combined with the hydro dynamically optimized design of the hull of the ship will allow the ship to successfully operate at certain modes of operation while notably reduce the pollutant emissions to the atmosphere. Besides the cogeneration heat obtained from the fuel cell system will be used to answer different heating needs on board the vesse

The efect on firms' Productivity of accessibility. The Spanish manufacturung sector

This paper evaluates the impact of accessibility on the productivity of Spanish manufacturing firms. We suggest the use of accessibility indicators to workers and commodities, integrating transport, land use, and individual components in their measurement, and computing real distances or travelling times using the Spanish full road network. The estimation is carried out in two steps. In the first one we estimate almost a hundred production functions using a panel of 155,937 firms along the 1999-2009 period from SABI database, applying Levinsohn and Petrin technique. From these estimations we derive the Total Factor Productivity function for year 2009, which is then explained in the second estimation step as a function of the accessibility indicators and additional control variables. Results evidence the crucial role of the accessibility to commodities, and a lesser but significant effect of workers’ accessibility on firms’ productivity