OPTIMAL CROP INSURANCE OPTIONS FOR ALABAMA COTTON-PEANUT PRODUCERS: A TARGET-MOTAD ANALYSIS

Target-MOTAD was used to determine the optimal crop insurance options for two representative cotton and peanut farms in southern Alabama. Results showed that, for one of the farms, no crop insurance option was risk reducing given the yield history. For the other farm, risk reduction involved shifting to higher levels of insurance coverage.Risk and Uncertainty,

Farmers and Social Security Reform

Agricultural Finance,

Dominance: An Objective Measure in Preschoolers

Psycholog

Symptomatology of Menopause as a Function of Estrogen Replacement Therapy and Sex Role

Psycholog

Farmers and Social Security Reform

Deals with the possible effect of the Social Security system reform on farmers. Background on the social security system being implemented; Summary of proposals for reform; Possible cost of implementing the personal savings account system

National Certification Initiative for Employment Support Professionals: Promoting Quality Integrated Employment Services

This article describes a recent certification initiative to build an international network of professionals who have the knowledge and skills to provide quality integrated employment services to individuals with a variety of disabilities. An overview of the history and conceptual framework guiding the development of the Employment Support Professional Certification Program will be followed by a presentation of findings from a preliminary survey study of 93 professionals who have been certified. Survey respondents identified both personal and professional motivations for pursuing the Certified Employment Support Professional (CESP) designation, including the desire to (a) achieve a sense of accomplishment and personal satisfaction, (b) demonstrate a professional standard of competence and commitment to the profession, and (c) garner professional credibility and enhanced opportunities for career advancement. The authors describe ongoing efforts and recommendations for validating the credentialing program and for increasing the number of certified professionals equipped to establish and expand equitable employment opportunities for individuals with disabilities

The Iowa Homemaker vol.30, no.5

Gift Wrapping Specials, Patricia Keast, page 3 What’s Afoot, Margaret Schaeffer, page 4 Finish That Seam, Barbara Short, page 5 Dance Club in Action, Patricia Binder, page 6 Plastic, Plastic, Everywhere, Marjorie Miller, page 8 Vidhyalaya, Universidad, Universitat, Peg Piaggi, page 9 What’s New, Nancy Voss, page 10 Cooks’ Christmas Favorites, Ruth Behnke, page 12 Alums in the News, Jane Novak, page 14 Here’s An Idea, Carol Dee Legg, page 16 Make It a Record Christmas, Barbara Short, page 2

A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis.

Primary biliary cholangitis (PBC) is typically associated with elevated serum bile acid levels and pruritus, but pruritus is often refractory to treatment with existing therapies. This phase 2 study assessed the efficacy and safety of maralixibat, a selective, ileal, apical, sodium-dependent, bile acid transporter inhibitor, in adults with PBC and pruritus. Adults with PBC and pruritus who had received ursodeoxycholic acid (UDCA) for ≥6 months or were intolerant to UDCA were randomized 2:1 to maralixibat (10 or 20 mg/day) or placebo for 13 weeks in combination with UDCA (when tolerated). The primary outcome was change in Adult Itch Reported Outcome (ItchRO™) average weekly sum score (0, no itching; 70, maximum itching) from baseline to week 13/early termination (ET). The study enrolled 66 patients (maralixibat [both doses combined], n = 42; placebo, n = 24). Mean ItchRO™ weekly sum scores decreased from baseline to week 13/ET with maralixibat (-26.5; 95% confidence interval [CI], -31.8, -21.2) and placebo (-23.4; 95% CI, -30.3, -16.4). The difference between groups was not significant (P = 0.48). In the maralixibat and placebo groups, adverse events (AEs) were reported in 97.6% and 70.8% of patients, respectively. Gastrointestinal disorders were the most frequently reported AEs (maralixibat, 78.6%; placebo, 50.0%). Conclusion: Reductions in pruritus did not differ significantly between maralixibat and placebo. However, a large placebo effect may have confounded assessment of pruritus. Lessons learned from this rigorously designed and executed trial are indispensable for understanding how to approach trials assessing pruritus as the primary endpoint and the therapeutic window of bile acid uptake inhibition as a therapeutic strategy in PBC

Development of an Extra-vehicular (EVA) Infrared (IR) Camera Inspection System

Designed to fulfill a critical inspection need for the Space Shuttle Program, the EVA IR Camera System can detect crack and subsurface defects in the Reinforced Carbon-Carbon (RCC) sections of the Space Shuttle s Thermal Protection System (TPS). The EVA IR Camera performs this detection by taking advantage of the natural thermal gradients induced in the RCC by solar flux and thermal emission from the Earth. This instrument is a compact, low-mass, low-power solution (1.2cm3, 1.5kg, 5.0W) for TPS inspection that exceeds existing requirements for feature detection. Taking advantage of ground-based IR thermography techniques, the EVA IR Camera System provides the Space Shuttle program with a solution that can be accommodated by the existing inspection system. The EVA IR Camera System augments the visible and laser inspection systems and finds cracks and subsurface damage that is not measurable by the other sensors, and thus fills a critical gap in the Space Shuttle s inspection needs. This paper discusses the on-orbit RCC inspection measurement concept and requirements, and then presents a detailed description of the EVA IR Camera System design