Repeated century-scale droughts over the past 13,000 yr near the Hudson River watershed, USA

Author Posting. © The Author(s), 2009. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Quaternary Research 75 (2011): 523-530, doi:10.1016/j.yqres.2011.01.006.Sediment and ground-penetrating radar data from Davis Pond near the Hudson River valley reveal past droughts in a historically humid region that presently supplies water to millions of people in and around New York City. A minimum of eleven sandy paleoshoreline deposits in the lake date from 13.4-0.6 cal ka BP. The deposits span 1500 to 200 years between bracketing radiocarbon dates, and intrude into lacustrine silts up to 9.0 m below the modern lake surface in a transect of six cores. Three lowstands, ca. 13.4-10.9, 9.2 and 8.2 cal ka BP indicate low regional moisture balance when low temperatures affected the North Atlantic region. Consistent with insolation trends, water levels rose from ca. 8.0 cal ka BP to present, but five low stands interrupted the rise and are likely associated with ocean-atmosphere interactions. Similar to evidence from other studies, the data from Davis Pond indicate repeated multi-century periods of prolonged or frequent droughts super-imposed on long-term regional trends toward high water levels. The patterns indicate that water supplies in this heavily populated region have continuously varied at multiple time scales, and confirm that humid regions such as the northeastern USA are more prone to severe drought than historically expected.We thank The Ocean and Climate Change Institute at Woods Hole Oceanographic Institution and NSF Earth System History program grants (EAR-0602380 to J. Donnelly and EAR-0602408 to B. Shuman) for supporting this research

Decay accelerating factor in guinea-pig reproductive organs

Decay accelerating factor (DAF, CD55) expressed in human reproductive organs and gametes is thought to play a pivotal role in protection against autologous complement activation in the genital tract. To further investigate the role of DAF in reproduction, we analysed DAF distribution in reproductive organs using guinea-pigs that express multiple DAF isoforms. In males, significant staining was observed in testis on the elongated spermatids and spermatozoa. Levels of DAF mRNA with a shorter 3′ untranslated region were significantly enhanced in testis from 9 weeks of age, indicating the presence of DAF mRNA and protein synthesis of spermatozoa DAF in late haploid germ cells. Epididymal spermatozoa appeared to express DAF on the inner acrosomal membrane as well as over their entire surface. Significant DAF expression was also observed on the epithelium of seminal vesicles from 4 weeks of age, with no increase thereafter in the mRNA. C3 mRNA was not detected in this tissue. In females, DAF was detected on the plasma membranes of oocytes through follicle development and on the apical region of uterine epithelium, although the levels of DAF mRNA in these tissues were low. In addition, DAF was selectively expressed on the apical region of ciliated oviductal epithelial cells. The apical region of the ciliated cells comprising the efferent ductule epithelium was also stained significantly, even at 12 days of age, while other epididymal epithelial cells were hardly stained at any age, suggesting that DAF is constitutively expressed on cilia