Rapid virological surveillance of community influenza infection in general practice

No abstract available

Results from the Scottish national HAI prevalence survey

A national point prevalence survey was undertaken over the period of one calendar year in Scotland from October 2005 to October 2006. The prevalence of healthcare-associated infection (HAI) was 9.5% in acute hospitals and 7.3% in non-acute hospitals. The highest prevalence of HAI in acute hospital inpatients was found in the following specialties: care of the elderly (11.9%), surgery (11.2%), medicine (9.6%) and orthopaedics (9.2%). The lowest prevalence was found in obstetrics (0.9%). The most common types of HAI in acute hospital inpatients were: urinary tract infections (17.9% of all HAI), surgical site infections (15.9%) and gastrointestinal infections (15.4%). In non-acute hospitals one in ten inpatients in two specialties (combined) medicine (11.4%) and care of the elderly (7.8%) was found to have HAI, and one in 20 inpatients in psychiatry (5.0%) had HAI. In non-acute hospital patients, urinary tract infections were frequent (28.1% of all HAI) and similarly skin and soft tissue infection (26.8% of all HAI). When combined, these two HAI types affected 4% of all the inpatients in non-acute hospitals. This is the first survey of its kind in Scotland and describes the burden of HAI at a national level

Homogenisation and analysis of an expanded long-term monthly rainfall network for the Island of Ireland (1850-2010)

Long-term precipitation series are critical for understanding emerging changes to the hydrological cycle. To this end we construct a homogenised Island of Ireland Precipitation (IIP) network comprising 25 stations and a composite series covering the period 1850-2010, providing the second- longest regional precipitation archive in the British-Irish Isles. We expand the existing catalogue of long-term precipitation records for the island by recovering archived data for an additional eight stations. Following bridging and updating of stations HOMER homogenisation software is used to detect breaks using pairwise and joint detection. Twenty-five breakpoints are detected across 14 stations, and the majority (20) are corroborated by metadata. Assessment of variability and change in homogenised and extended precipitation records reveal positive (winter) and negative (summer) trends. Trends in records covering the typical period of digitisation (1941 onwards) are not always representative of longer records. Furthermore, trends in post-homogenisation series change magnitude and even direction at some stations. While cautionary flags are raised for some series, confidence in the derived network is high given attention paid to metadata, coherence of behaviour across the network and consistency of findings with other long-term climatic series such as England and Wales precipitation. As far as we are aware, this work represents the first application of HOMER to a long- term precipitation network and bodes well for use in other regions. It is expected that the homogenised IIP network will find wider utility in benchmarking and supporting climate services across the Island of Ireland, a sentinel location in the North Atlantic

An evaluation of persistent meteorological drought using a homogeneous Island of Ireland precipitation network

This paper investigates the spatial and temporal properties of persistent meteorological droughts using the homogeneous Island of Ireland Precipitation (IIP) network. Relative to a 1961-1990 baseline period it is shown that the longest observed run of below average precipitation since the 1850s lasted up to 5 years (10 half-year seasons) at sites in southeast and east Ireland, or 3 years across the network as a whole. Dry- and wet-spell length distributions were represented by a first-order Markov model which yields realistic runs of below average rainfall for individual sites and IIP series. This model shows that there is relatively high likelihood (p=0.125) of a 5 year dry-spell at Dublin, and that near unbroken dry runs of 10 years or more are conceivable. We suggest that the IIP network and attendant rainfall deficit modelling provide credible data for stress testing water supply and drought plans under extreme conditions

Male frequent attenders of general practice and their help seeking preferences

Background: Low rates of health service usage by men are commonly linked to masculine values and traditional male gender roles. However, not all men conform to these stereotypical notions of masculinity, with some men choosing to attend health services on a frequent basis, for a variety of different reasons. This study draws upon the accounts of male frequent attenders of the General Practitioner's (GP) surgery, examining their help-seeking preferences and their reasons for choosing services within general practice over other sources of support. Methods: The study extends thematic analysis of interview data from the Self Care in Primary Care study (SCinPC), a large scale multi-method evaluation study of a self care programme delivered to frequent attenders of general practice. Data were collected from 34 semi-structured interviews conducted with men prior to their exposure to the intervention. Results: The ages of interviewed men ranged from 16 to 72 years, and 91% of the sample (n= 31) stated that they had a current health condition. The thematic analysis exposed diverse perspectives within male help-seeking preferences and the decision-making behind men's choice of services. The study also draws attention to the large variation in men's knowledge of available health services, particularly alternatives to general practice. Furthermore, the data revealed some men's lack of confidence in existing alternatives to general practice. Conclusions: The study highlights the complex nature of male help-seeking preferences, and provides evidence that there should be no 'one size fits all' approach to male service provision. It also provides impetus for conducting further studies into this under researched area of interest. © 2011 WPMH GmbH

Synthesis of Electrophiles Derived from Dimeric Aminoboranes and Assessing Their Utility in the Borylation of π Nucleophiles

Dimeric aminoboranes, [H2BNR2]2 (R = Me or CH2CH2) containing B2N2 cores, can be activated by I2, HNTf2 (NTf2 = [N(SO2CF3)2]), or [Ph3C][B(C6F5)4] to form isolable H2B(μ-NR2)2BHX (for X = I or NTf2). For X = [B(C6F5)4]− further reactivity, presumably between [H2B(μ-NMe2)2BH][B(C6F5)4] and aminoborane, forms a B3N3-based monocation containing a three-center two electron B-(μ-H)-B moiety. The structures of H2B(μ-NMe2)2BH(I) and [(μ-NMe2)BH(NTf2)]2 indicated a sterically crowded environment around boron, and this leads to the less common O-bound mode of NTf2 binding. While the iodide congener reacted very slowly with alkynes, the NTf2 analogues were more reactive, with hydroboration of internal alkynes forming (vinyl)2BNR2 species and R2NBH(NTf2) as the major products. Further studies indicated that the B2N2 core is maintained during the first hydroboration, and that it is during subsequent steps that B2N2 dissociation occurs. In the mono-boron systems, for example, iPr2NBH(NTf2), NTf2 is N-bound; thus, they have less steric crowding around boron relative to the B2N2 systems. Notably, the monoboron systems are much less reactive in alkyne hydroboration than the B2N2-based bis-boranes, despite the former being three coordinate at boron while the latter are four coordinate at boron. Finally, these B2N2 electrophiles are much more prone to dissociate into mono-borane species than pyrazabole [H2B(μ-N2C3H3)]2 analogues, making them less useful for the directed diborylation of a single substrate

Western Juniper (Juniperus occidentalis) and invasive annual grass mapping in Eastern Oregon

In 2011, the Institute for Natural Resources – Portland (INR) entered into an agreement with the Natural Resources Conservation Service through the Cooperative Ecosystem Study Unit to assist in evaluation of a targeted watershed restoration area in central Oregon. The primary objective of the agreement was to use remote sensing methodologies and widely available data sets to establish baseline landscape conditions that could be utilized by land managers as a planning tool and a measure of restoration project treatment success. Products and analysis developed by INR included: 1) A juniper percent canopy cover map for about 20 million acres in eastern Oregon and a juniper canopy cover increase/decrease map for a 17-year time interval between 1994 and 2011; 2) An exploratory analysis examining the feasibility of utilizing historic aerial photos to map historic juniper conditions; 3) A paired watershed analysis in Wheeler county examining outcomes of recent management activities; and 4) An exotic invasive annual map for 4.3 million acres spanning selected weed prioritization areas. The project was focused on using innovative remote sensing methods to identify the areas with existing juniper and invasive species concentrations. The resulting maps were intended to provide land managers with a preliminary planning tool describing existing baseline conditions across the region to help evaluate the effectiveness of different restoration treatments and identify priority areas for treatments