426 research outputs found
A Brighter Day for the Magic Lantern: Thoughts on the Impact of the New Copyright Act on Motion Pictures
New records of marine invertebrates from Ascension Island (central Atlantic)
The sea anemone Telmatactis forskalii, the zoanthid Isaurus tuberculatus, the nemertine Baseodiscus delineatus, the echinoderms Ophiocoma wendtii and Mithrodia clavigera, the molluscs Colubraria canariensis, Glyphepithema turtoni, Tonna pennata, Trivia candidula, Melanella eburnea, Melanella n.sp., Echineulima leucophaes, Stylocheilus striatus, Limaria hians, Pteria hirundo and Callistoctopus macropus, and the crustaceans Tetraclitella sp., Oxynaspis celata, Thor amboinensis and Parribacus antarcticus are recorded from Ascension Island for the first time. A new depth record is given for the sea anemone Telmatactis cricoides. An undescribed shrimp species of the genus Lysmata and the shrimp Lysmata moorei were observed to clean fish at night.info:eu-repo/semantics/publishedVersio
Access and nonâaccess site bleeding after percutaneous coronary intervention and risk of subsequent mortality and major adverse cardiovascular events:Systematic review and meta-analysis
Background: The prognostic impact of site-specific major bleeding complications after percutaneous coronary intervention (PCI) has yielded conflicting data. The aim of this study is to provide an overview of site-specific major bleeding events in contemporary PCI and study their impact on mortality and major adverse cardiovascular event outcomes. Methods and Results: We conducted a meta-analysis of PCI studies that evaluated site-specific periprocedural bleeding complications and their impact on major adverse cardiovascular events and mortality outcomes. A systematic search of MEDLINE and Embase was conducted to identify relevant studies and random effects meta-analysis was used to estimate the risk of adverse outcomes with site-specific bleeding complications. Twenty-five relevant studies including 2â400â645 patients that underwent PCI were identified. Both nonâaccess site (risk ratio [RR], 4.06; 95% confidence interval [CI], 3.21â5.14) and access site (RR, 1.71; 95% CI, 1.37â2.13) related bleeding complications were independently associated with an increased risk of periprocedural mortality. The prognostic impact of nonâaccess siteârelated bleeding events on mortality related to the source of anatomic bleeding, for example, gastrointestinal RR, 2.78; 95% CI, 1.25 to 6.18; retroperitoneal RR, 5.87; 95% CI, 1.63 to 21.12; and intracranial RR, 22.71; 95% CI, 12.53 to 41.15. Conclusions: The prognostic impact of bleeding complications after PCI varies according to anatomic source and severity. Nonâaccess site-related bleeding complications have a similar prevalence to those from the access site but are associated with a significantly worse prognosis partly related to the severity of the bleed. Clinicians should minimize the risk of major bleeding complications during PCI through judicious use of bleeding avoidance strategies irrespective of the access site used
A Northern Survey of Gamma-Ray Blazar Candidates
In preparation for GLAST, we have compiled a sample of blazar candidates to
increase the pool of well studied AGN from which GLAST counterparts will be
drawn. Sources were selected with our Figure of Merit (FoM) ranking; thus, they
have radio and X-ray properties very similar to the EGRET blazars.
Spectroscopic confirmation of these candidates is in progress, and more than
70% of these objects have been identified as flat spectrum radio quasars and BL
Lac objects. We present ~250 new optical blazar identifications based on
McDonald Observatory spectroscopy, 224 with redshifts. Of these, 167 are in our
FoM-selected set.
To motivate the Gamma-ray nature of these objects, we analyzed the current
release of the EGRET data for possible point sources at their radio positions.
We develop two distinct methods to combine multiple EGRET observations of a sky
position into a single detection significance. We report a detection of the
signal of the set of blazar candidates in the EGRET data at the > 3 sigma level
by both techniques. We predict that the majority of these blazar candidates
will be found by GLAST due to its increased sensitivity, duty cycle and
resolving power.Comment: ApJ Accepted (to appear 10 June 2005
Stroke following percutaneous coronary intervention : type-specific incidence, outcomes and determinants seen by the British Cardiovascular Intervention Society 2007-12
Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015. For permissions please email: [email protected] reviewedPostprin
Behind the Signs - a global review of fish sustainability information schemes
This paper presents the results of a global review of organisations that provide sustainable fisheries information â including ecolabels, recommendation lists and supermarkets â to consumers and supply chain intermediaries. It examined 17 organisations and key supermarkets that communicate on the sustainability of world fisheries and aquaculture products. Certification schemes assess a relatively small number of specific fisheries and indicate sustainability through labels. Recommendation lists cover more species and areas but in less detail. FAO guidelines for fisheries ecolabelling and aquaculture certification constituted the benchmarks with which improving conformance was found. However, significant variation in fisheriesâ assessment exists, affecting the accuracy and precision of information and advice provided. Inconsistent approaches and contradictory advice among certification schemes and recommendation lists potentially increase consumer confusion and reduce their credibility. The review identifies seven critical attributes schemes must address â scope, accuracy, independence, precision, transparency, standardisation and cost-effectiveness â and recommends that certification schemes and recommendation lists enhance their consistency and credibility through compliance with these attributes and FAO guidelines. Fish sustainability information schemes play an important role in securing a sustainable future for the oceans. Uptake of this reviewâs recommendations should reduce consumer confusion and increase confidence in the benefits of sustainable purchasing
Single circulating-tumor-cell-targeted sequencing to identify somatic variants in liquid biopsies in non-small-cell lung cancer patients
Non-small-cell lung cancer (NSCLC) accounts for most cancer-related deaths worldwide. Liquid biopsy by a blood draw to detect circulating tumor cells (CTCs) is a tool for molecular profiling of cancer using single-cell and next-generation sequencing (NGS) technologies. The aim of the study was to identify somatic variants in single CTCs isolated from NSCLC patients by targeted NGS. Thirty-one subjects (20 NSCLC patients, 11 smokers without cancer) were enrolled for blood draws (7.5 mL). CTCs were identified by immunofluorescence, individually retrieved, and DNA-extracted. Targeted NGS was performed to detect somatic variants (single-nucleotide variants (SNVs) and insertions/deletions (Indels)) across 65 oncogenes and tumor suppressor genes. Cancer-associated variants were classified using OncoKB database. NSCLC patients had significantly higher CTC counts than control smokers
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