INDAHNYA PERBEDAAN SEBAGAI TEMA PENCIPTAAN KARYA SENI LUKIS

Abstrak Manusia adalah makhluk yang indah dan yang menyenangi keindahan. Keindahan pada dasarnya meliputi sejumlah kualitas pokok tertentu yang terdapat pada suatu hal. Kualitas keindahan ditunjukkan oleh kesatuan (unity), keselarasan (harmony), kesetangkupan (symmetry), keseimbangan (balance), dan perlawanan (contrast). Tulisan ini menjelaskan berbagai macam keindahan dalam perbedaan yang pada dasarnya sudah ada sejak penciptaan segala sesuatu di dunia ini. Perbedaan yang asli menjadi sangat indah karena dibentuk oleh berbagai macam keunikan yang melekat pada setiap ciptaan, seperti jenis, ukuran, warna, bentuk, fungsi, isi dan lain-lain. Judul tulisan ini, yaitu “Indahnya Perbedaan” tidak hanya dapat diterapkan dalam kehidupan semua ciptaan yang lain, tetapi juga dapat diterapkan dalam kehidupan bersama sebagai satu masyarakat. Kata kunci: keindahan, perbedaan dan keaslia

INDAHNYA PERBEDAAN SEBAGAI TEMA PENCIPTAAN KARYA SENI LUKIS

Abstrak Manusia adalah makhluk yang indah dan yang menyenangi keindahan. Keindahan pada dasarnya meliputi sejumlah kualitas pokok tertentu yang terdapat pada suatu hal. Kualitas keindahan ditunjukkan oleh kesatuan (unity), keselarasan (harmony), kesetangkupan (symmetry), keseimbangan (balance), dan perlawanan (contrast). Tulisan ini menjelaskan berbagai macam keindahan dalam perbedaan yang pada dasarnya sudah ada sejak penciptaan segala sesuatu di dunia ini. Perbedaan yang asli menjadi sangat indah karena dibentuk oleh berbagai macam keunikan yang melekat pada setiap ciptaan, seperti jenis, ukuran, warna, bentuk, fungsi, isi dan lain-lain. Judul tulisan ini, yaitu “Indahnya Perbedaan” tidak hanya dapat diterapkan dalam kehidupan semua ciptaan yang lain, tetapi juga dapat diterapkan dalam kehidupan bersama sebagai satu masyarakat. Kata kunci: keindahan, perbedaan dan keaslia

KECERNAAN IN VITRO PAKAN KOMPLIT YANG MENGANDUNG LEVEL ALGA HIJAU (Ulva lactuca) YANG BERBEDA SEBAGAI PENGGANTI RUMPUT LAPANGAN

The objective of this experiment was to investigate the effect of substitution of U. lactuca to field grass on the in vitro digestibility of complete feed. Parameters measured were dry matter and organic matter digestibility, as well as total VFA and NH3 concentrations. This study was following a Completely Randomized Design (CRD) with 6 treatments and 4 replications, i.e: R0 = 60% field grass + 40% concentrate, R1 = 48% field grass + 40% concentrate + 12 % U. lactuca, R2 = 36% field grass + 40% concentrate + 24% U. lactuca, R3 = 24 % field grass + 40% concentrate + 36% U. lactuca, R4 = 12% field grass + 40% concentrate + 48 % U. lactuca, R5 = 60% U. lactuca + 40% concentrate. The results showed that treatments had significant effect (P<0.01) on DMD and OMD as well as the total VFA and NH3 concentrations. The result of statistical analysis showed that U. lactuca was able to completely replace grass in the complete feed because DMD and OMD were higher (67,99% and 70,04%) from control treatment (65,38% and 66,73%). While total VFA and NH3 concentration were significantly (P<0.01)  higher in R3 (147.66 mM and 9.80 mM) compared to other treatments. It was concluded that the optimum level of the inclusion of U. lactuca in replacing field grass was 36%. ABSTRAK Penelitian dilakukan dengan tujuan untuk menguji pengaruh level U. lactuca sebagai pengganti rumput alam terhadap kecernaan in vitro pakan komplit. Parameter yang diukur adalah kecernaan bahan kering dan bahan organik serta konsentrasi VFA total dan ammonia (NH3). Penelitian ini disusun berdasarkan Rancangan Acak Lengkap (RAL) dengan 6 perlakuan dan 4 ulangan, yaitu: R0 = 60% rumput alam + 40% konsentrat, R1 = 48% rumput alam + 40% konsentrat + 12 % U. lactuca, R2 = 36% rumput alam + 40% konsentrat + 24% U. lactuca, R3 = 24 % rumput alam + 40% konsentrat + 36% U. lactuca, R4 = 12% rumput alam + 40% konsentrat + 48% U. lactuca, R5 = 60% U. lactuca + 40% konsentrat. Hasil penelitian menunjukkan bahwa perlakuan berpengaruh sangat nyata (P<0,01) terhadap KcBK dan KcBO serta konsentrasi VFA total dan NH3. Hasil analisis statistik menunjukkan bahwa U. lactuca dapat sepenuhnya menggantikan rumput alam dalam pakan komplit karena KcBK dan KcBO lebih tinggi (67,99% dan 70,04%) dari perlakuan kontrol (65,38% dan 66,73). Sedangkan konsentrasi VFA total dan NH3 meningkat mencapai puncaknya pada perlakuan R3 (147.66 mM dan 9.80 mM). Berdasarkan hasil penelitian ini, disimpulkan bahwa level kecernaan optimum U. lactuca menggantikan rumput alam adalah sebesar 36%

Interstitial Lung Abnormalities After Hospitalization for Covid-19 in Patients With Cancer: A Prospective Cohort Study

INTRODUCTION: Survivors of SARS-CoV-2 pneumonia often develop persistent respiratory symptom and interstitial lung abnormalities (ILAs) after infection. Risk factors for ILA development and duration of ILA persistence after SARS-CoV-2 infection are not well described in immunocompromised hosts, such as cancer patients. METHODS: We conducted a prospective cohort study of 95 patients at a major cancer center and 45 patients at a tertiary referral center. We collected clinical and radiographic data during the index hospitalization for COVID-19 pneumonia and measured pneumonia severity using a semi-quantitative radiographic score, the Radiologic Severity Index (RSI). Patients were evaluated in post-COVID-19 clinics at 3 and 6 months after discharge and underwent comprehensive pulmonary evaluations (symptom assessment, chest computed tomography, pulmonary function tests, 6-min walk test). The association of clinical and radiological factors with ILAs at 3 and 6 months post-discharge was measured using univariable and multivariable logistic regression. RESULTS: Sixty-six (70%) patients of cancer cohort had ILAs at 3 months, of whom 39 had persistent respiratory symptoms. Twenty-four (26%) patients had persistent ILA at 6 months after hospital discharge. In adjusted models, higher peak RSI at admission was associated with ILAs at 3 (OR 1.5 per 5-point increase, 95% CI 1.1-1.9) and 6 months (OR 1.3 per 5-point increase, 95% CI 1.1-1.6) post-discharge. Fibrotic ILAs (reticulation, traction bronchiectasis, and architectural distortion) were more common at 6 months post-discharge. CONCLUSIONS: Post-COVID-19 ILAs are common in cancer patients 3 months after hospital discharge, and peak RSI and older age are strong predictors of persistent ILAs

Variants in GNAI1 cause a syndrome associated with variable features including developmental delay, seizures, and hypotonia

Purpose: Neurodevelopmental disorders (NDDs) encompass a spectrum of genetically heterogeneous disorders with features that commonly include developmental delay, intellectual disability, and autism spectrum disorders. We sought to delineate the molecular and phenotypic spectrum of a novel neurodevelopmental disorder caused by variants in the GNAI1 gene. Methods: Through large cohort trio-based exome sequencing and international data-sharing, we identified 24 unrelated individuals with NDD phenotypes and a variant in GNAI1, which encodes the inhibitory Gαi1 subunit of heterotrimeric G-proteins. We collected detailed genotype and phenotype information for each affected individual. Results: We identified 16 unique variants in GNAI1 in 24 affected individuals; 23 occurred de novo and 1 was inherited from a mosaic parent. Most affected individuals have a severe neurodevelopmental disorder. Core features include global developmental delay, intellectual disability, hypotonia, and epilepsy. Conclusion: This collaboration establishes GNAI1 variants as a cause of NDDs. GNAI1-related NDD is most often characterized by severe to profound delays, hypotonia, epilepsy that ranges from self-limiting to intractable, behavior problems, and variable mild dysmorphic features

GW190412: Observation of a Binary-Black-Hole Coalescence with Asymmetric Masses

We report the observation of gravitational waves from a binary-black-hole coalescence during the first two weeks of LIGO’s and Virgo’s third observing run. The signal was recorded on April 12, 2019 at 05∶30∶44 UTC with a network signal-to-noise ratio of 19. The binary is different from observations during the first two observing runs most notably due to its asymmetric masses: a ∼30 M_⊙ black hole merged with a ∼8 M_⊙ black hole companion. The more massive black hole rotated with a dimensionless spin magnitude between 0.22 and 0.60 (90% probability). Asymmetric systems are predicted to emit gravitational waves with stronger contributions from higher multipoles, and indeed we find strong evidence for gravitational radiation beyond the leading quadrupolar order in the observed signal. A suite of tests performed on GW190412 indicates consistency with Einstein’s general theory of relativity. While the mass ratio of this system differs from all previous detections, we show that it is consistent with the population model of stellar binary black holes inferred from the first two observing runs

Properties and Astrophysical Implications of the 150 M_⊙ Binary Black Hole Merger GW190521

The gravitational-wave signal GW190521 is consistent with a binary black hole (BBH) merger source at redshift 0.8 with unusually high component masses, 85⁺²¹₋₁₄ M_⊙ and 66⁺¹⁷₋₁₈ M_⊙, compared to previously reported events, and shows mild evidence for spin-induced orbital precession. The primary falls in the mass gap predicted by (pulsational) pair-instability supernova theory, in the approximate range 65–120 M_⊙. The probability that at least one of the black holes in GW190521 is in that range is 99.0%. The final mass of the merger 142⁺²⁸₋₁₆ M_⊙) classifies it as an intermediate-mass black hole. Under the assumption of a quasi-circular BBH coalescence, we detail the physical properties of GW190521's source binary and its post-merger remnant, including component masses and spin vectors. Three different waveform models, as well as direct comparison to numerical solutions of general relativity, yield consistent estimates of these properties. Tests of strong-field general relativity targeting the merger-ringdown stages of the coalescence indicate consistency of the observed signal with theoretical predictions. We estimate the merger rate of similar systems to be 0.13_(-0.11)^(+0.30) Gpc⁻³ yr⁻¹. We discuss the astrophysical implications of GW190521 for stellar collapse and for the possible formation of black holes in the pair-instability mass gap through various channels: via (multiple) stellar coalescences, or via hierarchical mergers of lower-mass black holes in star clusters or in active galactic nuclei. We find it to be unlikely that GW190521 is a strongly lensed signal of a lower-mass black hole binary merger. We also discuss more exotic possible sources for GW190521, including a highly eccentric black hole binary, or a primordial black hole binary