158 research outputs found
On the Challenges of Collaborative Data Processing
The last 30 years have seen the creation of a variety of electronic
collaboration tools for science and business. Some of the best-known
collaboration tools support text editing (e.g., wikis). Wikipedia's success
shows that large-scale collaboration can produce highly valuable content.
Meanwhile much structured data is being collected and made publicly available.
We have never had access to more powerful databases and statistical packages.
Is large-scale collaborative data analysis now possible? Using a quantitative
analysis of Web 2.0 data visualization sites, we find evidence that at least
moderate open collaboration occurs. We then explore some of the limiting
factors of collaboration over data.Comment: to appear as a chapter in an upcoming book (Collaborative Information
Behavior
Interaction of (3-Aminopropyl)triethoxysilane With Late Ar-N 2 Afterglow: Application to Nanoparticles Synthesis
International audienceFrom results of in situ FTIR absorption and optical emission spectroscopy, the interaction of (3âaminopropyl)triethoxysilane (APTES) with late Ar-N2 afterglow is shown to occur mainly with N atoms. They react preferentially with carbon from CHx groups in the precursor, leading to the synthesis of CN bonds. No production of NH radical is observed, demonstrating the lack of direct reaction between active nitrogen and APTES. The -NH2 group is not affected by the afterglow. One of the C-C bonds of the propylamine group in the APTES is likely broken. These nanoparticles present secondary amides due to reactions with active nitrogen. They are amorphous and react in air to produce a salt
Performances comparĂ©es du HDL-cholestĂ©rol et du ratio cholestĂ©rol total/HDL pour le dĂ©pistage du syndrome mĂ©tabolique chez des adultes du Sud-BĂ©nin (Afrique de lâOuest)
Les critĂšres de dĂ©finition du Syndrome mĂ©tabolique (SMet) nâidentifient pas convenablement les sujets dâorigine africaine Ă risque. Lâobjectif Ă©tait de dĂ©terminer lequel du ratio cholestĂ©rol total/HDL-cholestĂ©rol (CT/HDL-C) et du HDL-CholestĂ©rol est le meilleur prĂ©dicteur du SMet chez les adultes bĂ©ninois. LâĂ©tude de type transversal, issue dâune enquĂȘte longitudinale sur le risque cardiomĂ©tabolique a inclu 416 sujets ĂągĂ©s de 29 Ă 69 ans. Les composantes du SMet considĂ©rĂ©es sont : lâobĂ©sitĂ© abdominale, la tension artĂ©rielle Ă©levĂ©e, la glycĂ©mie Ă©levĂ©e, le HDL-C bas et les triglycĂ©rides Ă©levĂ©s. La comparaison des aires sous les courbes (AUC) de la « fonction dâefficacitĂ© du rĂ©cepteur » (ROC) de prĂ©diction de lâexistence deux composantes du SMet autre que lâobĂ©sitĂ© abdominale, a permis de dĂ©terminer le meilleur prĂ©dicteur. Les prĂ©valences du SMet Ă©taient de 13,9% selon la dĂ©finition harmonisĂ©e, 12,3% lorsque le HDL-C bas est remplacĂ©e par CT/HDL-C Ă©levĂ©. Les prĂ©valences du HDL-bas et du CT/HDL-C Ă©levĂ© sont de 37,7% et 22,6%, respectivement. Pour le dĂ©pistage du SMet, lâAUC du CT/HDL-C est de 0,69 (IC 95% 0,61-0,77) chez les femmes et 0,68 (IC 95% 0,59-0,77) chez les hommes. LâAUC du HDL-C est de 0,45 (IC 95% 0,37-0,53) chez les femmes et 0,40 (IC 95% 0,30-0,44) chez les hommes. Le HDL-C et le CT/HDL-C ont une faible capacitĂ© prĂ©dictive pour le SMet, mais la composante CT/HDL-C prĂ©dit mieux le SMet que le HDL-C isolĂ©. Toutefois, lâutilisation de lâun ou lâautre des deux paramĂštres ne modifie pas substantiellement la prĂ©valence du SMet dans la population dâĂ©tude.© 2016 International Formulae Group. All rights reserved.Mots clĂ©s: Syndrome mĂ©tabolique, lipoprotĂ©ines, ratio CT/HDL-C, Sud-BĂ©ninEnglish Title: Comparative performance of HDL-cholesterol and total cholesterol / HDL ratio for screening of metabolic syndrome in Southern Benin adults (West Africa)English AbstractCurrent definition criteria of the metabolic syndrome (MetS) do not adequately identify at risk African origin subjects. The objective was to determine which of total cholesterol/HDL-cholesterol (TC/HDL-C) and HDL-cholesterol is the best predictor of metabolic syndrome (SMet) in Benin adults. This cross-sectional study was nested in a four-year follow-up study on cardiometabolic risk factors and included 416 adults aged 29-69 years. Components of MetS considered were abdominal obesity, high blood pressure (BP), high fasting glucose, low HDL-C and high triglycerides. Areas under the "Receiver operator characteristic" curves (AUC)for CT/HDL-C and HDL-C in predicting the presence of at least two other components of SMet were compared in order to determine the best predictor of SMet. The prevalence of SMet was 13.9%, when replacing low HDL-C by high TC/HDL-C and 15.3% when both dyslipidemia indicators are combined. The prevalence of low HDL-C and high TC/HDL-C was 37.7% and 22.6%, respectively (p<0.001). Screening for SMet, the AUC of TC/HDL-C were 0.69 (95% CI 0.61-0.77) for women and 0.68 (95% CI 0.59-0.77) in men. The AUC of HDL-C were 0.45 (95% CI 0.37-0.53) for women and 0.40 (95% CI 0.30-0.44) for men. Both TC/HDL-C and HDL-C showed some weak predictive values for SMet, but TC/HDL-C ratio predicted SMet better than HDL-C.© 2016 International Formulae Group. All rights reserved.Keywords: Metabolic syndrome, lipoprotein, ratio CT/HDL-C, Southern Beni
Ćdipe stories au NTH8 ou lâabsolue libertĂ©
Sylvie Mongin-Algan et Guy Naigeon, appuyĂ©s par les comĂ©diens du compagnonnage, rouvrent lâenquĂȘte Ćdipe sur la trace de questions et de preuves passĂ©es inaperçues. De Sophocle, Ă Jouanneau, Huston ou Freud, en passant par Shakespeare, Cocteau, Mouawad : leurs Ă©crits, parmi bien dâautres, guideront leur pas dans cette recrĂ©ation dâun mythe connu de tous. Câest lâoccasion pour nous de vous convier au Nouveau ThĂ©Ăątre du 8e, lieu de crĂ©ation dont le modus vivendi et la libertĂ© artistique sont u..
Utilisation du test GeneXpert pour le diagnostic de la tuberculose au service des maladies infectieuses du CHNU de Fann
Introduction: Nous avons rĂ©alisĂ© ce travail pour montrer notre expĂ©rience dâutilisation du GeneXpert et Ă©valuer son apport dans la confirmation du diagnostic de la tuberculose. MĂ©thodes: Etude prospective descriptive et analytique de janvier Ă DĂ©cembre 2013. RĂ©sultats: Quatre vingt quatorze patients ont bĂ©nĂ©ficiĂ© du geneXpert pour le dĂ©pistage de la tuberculose toute localisation confondue. Le geneXpert avait Ă©tĂ© positif dans 62% des cas. Les images radiologiques fortement Ă©vocatrices de tuberculose Ă©tait associĂ©es Ă un geneXpert positif dans 25% des cas. La recherche de BAAR rĂ©alisĂ©e chez 55 patients Ă©tait positive dans 9 cas (16%). Le geneXpert Ă©tait positif sur 46 frottis nĂ©gatif (54%)et dans 89% sur les frottis positifs. La prĂ©valence de la tuberculose extrapulmonaire Ă©tait de 34%. Le taux de positivitĂ© Ă©tait variable en fonction du type de prĂ©lĂšvement. Deux cas de rĂ©sistance Ă la rifampicine ont Ă©tĂ© dĂ©tectĂ©es. Conclusion: Le geneXpert a Ă©tĂ© dâun grand apport pour le diagnostic de la tuberculose pulmonaire et extrapulmonaire mais la bacilloscopie reste incontournable.Pan African Medical Journal 2016; 2
Guidelines for the diagnosis and management of chylomicron retention disease based on a review of the literature and the experience of two centers
Familial hypocholesterolemia, namely abetalipoproteinemia, hypobetalipoproteinemia and chylomicron retention disease (CRD), are rare genetic diseases that cause malnutrition, failure to thrive, growth failure and vitamin E deficiency, as well as other complications. Recently, the gene implicated in CRD was identified. The diagnosis is often delayed because symptoms are nonspecific. Treatment and follow-up remain poorly defined
BEEHOPE: um projeto de conservação das subespécies nativas de abelha da Europa Ocidental (linhagem M) à escala Europeia
O projeto BEEHOPE, com o tĂtulo original âHoneybee conservation centres in western Europe - an innovative strategy using sustainable beekeeping to reduce honeybee declineâ, foi um dos 10 aprovados na ĂĄrea da biodiversidade do 5Âș concurso transnacional (2013-2014) BiodivErsA/FACCE-JPI (http://www.biodiversa.org/766), subordinado ao tema âPromover sinergias e reduzir o compromisso entre o abastecimento de alimentos, biodiversidade e serviços dos ecossistemasâ. A diversidade nativa das populaçÔes de abelha melĂfera (Apis mellifera) da linhagem da Europa ocidental (M) tem vindo a ser crescentemente ameaçada pela introdução massiva de colĂłnias da linhagem da Europa oriental (C, onde se incluem as subespĂ©cies A. m. ligustica, A. m. carnica, A. m. macedĂłnica etc.), e tambĂ©m por outros fatores biĂłticos (Varroa e vĂrus associados, Nosema etc.) e abiĂłticos (pesticidas, perda e fragmentação de habitat, alteraçÔes climĂĄticas etc.). Ă neste contexto que surge o projeto BEEHOPE, o qual tem por objetivo Ășltimo contribuir para a conservação da diversidade genĂ©tica das populaçÔes de abelha melĂfera da linhagem M.info:eu-repo/semantics/publishedVersio
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