187 research outputs found
SYNERGISTIC EFFECT OF SILVER NANOPARTICLES WITH DOXYCYCLINE AGAINST KLEBSIELLA PNEUMONIA
Objective: Green synthesis, characterization of silver nanoparticles (AgNPs) and study of the synergistic effect of AgNPs with antibiotic doxycycline against Klebsiella pneumonia.Methods: AgNps were synthesized from bacteria isolated from samples obtained from petroleum soil. After characterization of the nanoparticles, the antibacterial activity of the nanoparticle was studied, and simultaneously the same nanoparticle was used in combination with doxycycline antibiotic.Results: It was observed that compared to the effects of AgNps and antibiotic alone, the collective effect on both of them was more evident, which indicate the synergistic effect of the two components.Conclusion: These findings highlight the potential for AgNPs to enhance the activity of doxycycline antibiotic against Klebsiella pneumonia infections.Keywords: Silver nanoparticle, Green Synthesis, Klebsiella Pneumonia, Doxycyclin
Repression of the alkaline phosphatase of Vibrio cholerae
The synthesis of alkaline phosphatase by two strains of Vibrio cholerae belonging to the Inaba and Ogawa serotypes has been examined in relation to the phosphate concentration of the culture medium. The synthesis of the enzyme in both strains was repressed in cells grown in the presence of a high concentration of inorganic phosphate. Lowering the phosphate content of the growth medium led to a derepression of enzyme activity. The presence of glucose in low phosphate medium stimulated the degree of derepression. The synthesis of the enzyme by strain Inaba 569B was more sensitive to inorganic phosphate than that of strain Ogawa 154. The enzyme was presumably located in the periplasmic space since it was released when the organisms were converted to spheroplasts
Enterotoxin production, DNA repair and alkaline phosphatase of Vibrio cholerae before and after animal passage
Summary: Three strains of Vibrio cholerae differing in biotype, serotype and/or toxinogenicity were studied. The capability for dark repair of DNA and stability of alkaline phosphatase decreased concomitantly with toxinogenicity on laboratory passage of highly enterotoxinogenic strain 569B. These properties could be restored by passaging strain 569B once through a guinea-pig
N-(6-{2-[6-(2,2-Dimethylpropanamido)-2-pyridyl]ethyl}-2-pyridyl)-2,2-dimethylpropanamide
The title compound, C22H30N4O2, lies about a crystallographic inversion center. The whole molecule is disordered over two positions with a refined occupancy ratio of 0.636 (10):0.364 (10). The pyridine rings are approximately planar, with maximum deviations of 0.033 (10) and 0.063 (17) Å for the major and minor components, respectively. The mean planes of the pyridine rings form dihedral angles of 17 (2)° in the major component and 18 (2)° in the minor component with the respective formamide groups attached to them. In the crystal packing, intermolecular N—H⋯O and C—H⋯O hydrogen bonds link the molecules into two-dimensional networks parallel to the ab plane
MEASURING LOSS, LATENCY AND JITTER BASED ON APPLICATION TYPES TO IMPROVE APPLICATION ROUTING DECISIONS
Current Software Defined Wide Area Network (SDWAN) solutions typically utilize a Service Level Agreement (SLA) definition in conjunction with policy to match and classify traffic types in order to direct traffic over SDWAN tunnels. An SLA definition can include values of loss, latency, and jitter, which are measured via a Bi-directional Forwarding Detection (BFD) channel that exists between two Transport Locators (TLOCs). These values collectively represent the liveliness of a network including the status of the BFD link. In current implementations, BFD control messages are sent with a high priority Differentiated Services Code Point (DSCP) marking, such as \u2748\u27. SLA metrics based on such a high priority packet, however, do not reflect the priority that it will be received by the actual data that flows through an edge device. Techniques presented herein address such issues by providing for a more accurate representation or measurements of loss, latency, and jitter for various desired traffic profiles for a network along with capabilities to use such measurements to direct different traffic types to correct tunnels
Initial‐valued first‐order fuzzy differential equation in Bi‐level inventory model with fuzzy demand
In the present paper, two methods for the solution of an initial valued first ordered fuzzy differential equation are presented and applied in a fuzzy EOQ model. The constructed model is a bi‐level inventory problem involving wholesaler‐retailers‐customers. The wholesaler buys and sells the item instantaneously to several retailers. In the next level, the retailers sell the units to customers with a time dependent imprecise demand, which introduce the fuzzy nature in the differential equation. The selling price of the item is a step‐wise time dependent decreasing function. The fuzzy objectives are transformed into crisp one following fuzzy extension principle and centroid formula. The model is illustrated through Interactive Fuzzy Decision Making (IFDM) and Multi Objective Genetic Algorithm (MOGA) and the results from two methods are compared.
First Published Online: 14 Oct 201
Co-Infection of HSV in Gonococcal Urethritis Patients
Co-infection with two different pathogens may alter the classical clinical course that manifests infection as single pathogen. In STIs, such co-infection may trigger the reactivation of a latent infection, and syndromic approach may not be insufficient to free the host of the entire gamut of infectivity agents. Present study analyzed appropriate samples for Neisseria gonorrheae and HSV from 200 patients presented to STI clinic. Gonorrhea was detected in 4% and HSV in 5% of patients. 25% of gonorrhea patients had HSV-2 co-infection with an overall 4.5% yield of subclinical HSV cases which would have been missed leading to inappropriate treatment, risk of recurrence and transmission to contacts. Awareness regarding encounter with multiple infections is necessary for effective management
FPGA based Security Login System using GSM with OTP Generation
Security of system is major concern in this age of high-tech infrastructure. In today\u27s materialistic world, security holds an in dispensable place. Security in every aspect is highly desirable may be at home or at office etc. as thefts and robberies are increasing day by day. To overcome this security threat, a security system has been proposed using GSM technology, by generating One Time Password and implementing in FPGA. As FPGAs offer all of the features needed to implement most complex designs. This security system activates, authenticates and validates the user and then unlocks the system. This project attempts to create security login systemwhere the user is granted access if he enters the correct predefined password and is denied access if he enter the wrong password. When password is entered GSM gets activated and send SMS to user\u27s mobile phone, after authentication random OTP is generated and should be verified such that the system gets accessed. In every 3 minutes this OTP verification code will change and is valid for 3 minutes. The outcome of each and all would be available in the LCD of the Spartan 3E board. VHDL codes are used to design this system using Xilinx ISE 9.2i
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