366 research outputs found
RADIX SORT WITH REDUCED TIME COMPLEXITY
Sorting is a technique that arranges data in a specific order, so that they can be accessed easily. Radix sort is one of the techniques. Processors execute programs as per the definition of codes. Time of execution depends on the design of the program. Complex programs take more time of execution. This technical paper explains radix sort algorithm that has been made simpler to reduce time complexity
A Novel Link Between Akt1 And Twist1 In Ovarian Tumor Cell Motility And Invasiveness
Ovarian cancer results in more deaths per year than any other cancer of the female reproductive system. The low survival rate is partly due to the lack of early detection and the susceptibility to relapse. The AKT serine threonine kinase plays a pivotal role in hallmark cellular processes for the progression of ovarian cancer, including tumor cell growth and migration. Therapeutic targeting of pan-AKT has been problematic, in part due to feedback mechanisms and crosstalk with other pathways. The hypothesis for this study is that AKT 1, -2 and -3 isoforms may have different roles and regulate cell processes in uniquely varied ways. A transgenic mouse model that expresses the SV40 T-antigen viral oncogene and is known to have dramatically increased susceptibility to ovarian cancer was utilized, and it had genetic inactivation of either AKT1 or AKT2 through targeted deletion of the individual genes because these isoforms have been implicated in this cancer. Primary ovarian tumor cell cultures were established and found to exhibit different morphology, proliferation and migration that may indicate a different role for the AKT1 and AKT2 isoforms in these contexts. Ovarian tumor cells with absence of AKT1 predominantly exhibited reduced cell migration when compared to cells with retention of AKT1 and absence of AKT2. Since AKT is known to be important for epithelial-mesenchymal transition (EMT), a process potentially associated with tumor cell metastasis, the expression of transcription factors implicated in EMT was assessed by real-time array analysis in ovarian tumor cells knocked-out for either AKT1 or AKT2. Twist1, one of the major players in EMT, was not detectable in the cells missing the AKT1 isoform. Results indicate an association of Twist1 with AKT1 in EMT and migration of ovarian tumors cells. This finding is significant because AKT2 has been implicated as the major player of cell migration in human breast cancer iv cells. Collectively, these findings support a tissue specific role of the AKT isoforms, and may provide insights regarding the most useful cell context in order to target components of the AKT signaling pathway indirectly affecting EMT in order to prevent tumor progression in patients with ovarian and perhaps other types of cancer
Domination integrity of total graphs
The domination integrity of a simple connected graph G is a measure of vulnerability of a graph. Here we determine the domination integrity of total graphs of path Pn, cycle Cn and star K1,n.Publisher's Versio
Allogeneic transplantation in elderly patients ≥65 years with non-Hodgkin lymphoma: A time-trend analysis
The system, control and cultural management of the Indian diamond firms in countries like Hong Kong and Antwerp compared to India.
In the era of globalization, internalization of business is at its peak. In order to survive the severe competition from the competitors, the companies expand their business operations across international boundaries. Due to the growing importance of globalization in relation to business context, the need to study the cross-cultural management is very essential. Therefore, various researchers have studied the different aspects of cross-cultural management. However, very little research has been conducted on the cross-cultural differences that are faced by the large organizations. This research aims to study these cultural differences in relation to the diamond industry which is a booming industry with a very vast scale globally. The findings of this study are derived from a qualitative approach as the topic under consideration cannot be quantified. Semi-structured interviews of the owners as well as the employees of the Indian diamond trading companies were conducted in order to gain an insight of the issues faced by them in working cross-culturally. Also, ethnographic research was conducted by the researcher. The findings of the research conducted provide an in-depth knowledge of the major cross-cultural differences faced by the companies or its employees. These findings are then further analyzed in detail and its impact on the business existence is also studied. It also mentions the various ways in which companies or the employee’s can handle the cultural differences and run the business successfully. Different cultural problems can be faced by the Indian companies in other countries like Hong Kong and Antwerp. However, this research attempts to point out few of the main cross-cultural issues faced by these companies
Coupled parameterized reduced order modelling of thermomechanical phenomena arising in blast furnaces
Blast furnace operations are subjected to temperatures up to 1500º C, causing high thermal stresses in blast furnace hearth walls. First, an axisymmetric isotropic homogeneous model is introduced and solved using finite element method. Next, we introduced the relevant geometric parameters and material parameters. We used the Proper Orthogonal Decomposition (POD) to construct the reduced basis space. For the computation of degrees of freedom, we used Galerkin projection and artificial neural network. Further to the simplified model, we introduced the mathematical model characterised by temperature dependence of material properties and presence of different materials. Homogenization is used to identify an equivalent orthotropic material from the periodic assembly of homogeneous isotropic materials. Finite element formulation is used to solve the complex thermomechanical model. Finally, we extended the POD-artificial neural network approach to the complex thermomechanical model
Microscopic derivation of multi-channel Hubbard models for ultracold nonreactive molecules in an optical lattice
Recent experimental advances in the cooling and manipulation of bialkali
dimer molecules have enabled the production of gases of ultracold molecules
that are not chemically reactive. It has been presumed in the literature that
in the absence of an electric field the low-energy scattering of such
nonreactive molecules (NRMs) will be similar to atoms, in which a single
-wave scattering length governs the collisional physics. However, in Ref.
[1], it was argued that the short-range collisional physics of NRMs is much
more complex than for atoms, and that this leads to a many-body description in
terms of a multi-channel Hubbard model. In this work, we show that this
multi-channel Hubbard model description of NRMs in an optical lattice is robust
against the approximations employed in Ref. [1] to estimate its parameters. We
do so via an exact, albeit formal, derivation of a multi-channel resonance
model for two NRMs from an ab initio description of the molecules in terms of
their constituent atoms. We discuss the regularization of this two-body
multi-channel resonance model in the presence of a harmonic trap, and how its
solutions form the basis for the many-body model of Ref. [1]. We also
generalize the derivation of the effective lattice model to include multiple
internal states (e.g., rotational or hyperfine). We end with an outlook to
future research.Comment: 19 pages, 4 figure
INVESTIGATION OF CAPACITY GAINS IN MIMO CORRELATED RICIAN FADING CHANNELS SYSTEMS
This paper investigate the effect of Rician fading and correlation on the capacity and diversity of MIMO channels. The use of antenna arrays at both sides of the wireless communication link (MIMO systems) can increase channel capacity provided the propagation medium is rich scattering or Rayleigh fading and the antenna arrays at both sides are uncorrelated. However, the presence of line-of-sight (LOS) component and correlation of real world wireless channels may affect the system performance. Along with that we also investigate power distribution methods for higher capacity gains and effect of CSI at the transmitter on the capacity for range of SNR. Our investigation follows capacity gain as function of number of antennas and signal-to-noise (SNR) power ratio Block and frequency nonselective Rician fading channel is assumed, and the effect of Rician factor (L) and the correlation parameter (ρ) on the capacity and diversity gains of MIMO channels are found. Inde
Discontinuous Galerkin Model Order Reduction of Geometrically Parametrized Stokes Equation
The present work focuses on the geometric parametrization and the reduced order modeling of the Stokes equation. We discuss the concept of a parametrized geometry and its application within a reduced order modeling technique. The full order model is based on the discontinuous Galerkin method with an interior penalty formulation. We introduce the broken Sobolev spaces as well as the weak formulation required for an affine parameter dependency. The operators are transformed from a fixed domain to a parameter dependent domain using the affine parameter dependency. The proper orthogonal decomposition is used to obtain the basis of functions of the reduced order model. By using the Galerkin projection the linear system is projected onto the reduced space. During this process, the offline-online decomposition is used to separate parameter dependent operations from parameter independent operations. Finally this technique is applied to an obstacle test problem.The numerical outcomes presented include experimental error analysis, eigenvalue decay and measurement of online simulation time
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