2,105 research outputs found
Custom Surrogate Host for ActiveX In-Process Servers
This paper describes the design, implementation and evaluation of
AX Host, a custom surrogate host for ActiveX in-process servers. AX Host aims to
give ActiveX client applications improved stability by using software fault
isolation
Remote Tool For Controlling User Interface Of Mobile Applications
It will be very useful for users to have an opportunity to control external visual appearance of their applications, especially the mobile one. This potentially functional feature provoked the authors beginning a research on development of mediator tools, which can help users for that. In this paper, will be presented a flexible tool, that controls remotely and dynamically visual appearance of cross platform mobile native shopping applications. Its architecture is multi-layered and later can be used like a base extension for other connecting tools. They can manage UI mobile applications from different types
INFLUENCE OF METEOROLOGICAL ELEMENTS IN ACCIDENTS IN ENTERPRISES WITH RADIOACTIVE ELEMENTS OR DANGEROUS CHEMICAL SUBSTANCES IN BULGARIA
In the analysis of the meteorological elements that influence the spread of radioactive particles, radioactive isotopes and dangerous chemical substances on the territory of Bulgaria, the winds and air currents that form in the airspace over Bulgaria are considered. These are the main meteorological elements that most strongly influence the change in the radioactive background. Another element that has an impact is precipitation in its various manifestations - horizontal and vertical in appearance and depending on the aggregate state of the water. Due to their negligible influence on the radiation environment, we will exclude the remaining meteorological elements from the factors forming the natural indicators of the state of the atmosphere, water and soil. Their influence in areas where there are located large enterprises working with such substances is presented.The report examines the influence of the main factor - the movement of air masses at different altitudes in the atmosphere in the Ludogorie region and the Danube River as an area where NPPs are located in Bulgaria and Romania and which, in the event of an accident, would cause the greatest consequences. The winds in 3 cities from this region, which are located near these enterprises, are described and the corresponding analysis is made.
Are blood cytokines reliable biomarkers of allergic disease diagnosis and treatment responses?
With the development of targeted therapies for allergic diseases, the need for biomarkers supporting disease diagnosis and management has increased. Recent research has elucidated the pattern of cytokines and their distinct roles in the pathogenesis of allergic diseases. This means that cytokines should be considered as biomarkers. In this review article, we summarize published findings and critically discuss the use of cytokine measurements in association with disease diagnosis and management. Among the variety of suggested cytokines, thymus and activation-regulated chemokine (TARC) stands out and can indeed serve as a biomarker of atopic dermatitis. Both biologic characteristics and technical issues determine the reliability and limit the use of blood cytokines as biomarkers
Mathematical model of composite fibre-glass aramide-wired cord rheological properties
This paper describes the rheological properties of composite fibre-glass aramide-wired cords which, in its turn, are applied in large-sized structures for space systems. Based on experimental data a new mathematical model describing creeping and relaxation of composite cords is proposed. This model defines the operation time of the composite cords to be 15 years
Influence of Protective Gas Content on Quality of Welded Joint While Welding With Impulse Supply of Electrode Wire
Currently one of the advanced ways of obtaining quality welded joint while welding of medium alloy martensitic-bainitic steel is the one with impulse supply of electrode wire in gas mixture Ar(70%±3%)+СО2(30%±3%). Results of experimental studies proved that application of protective gas Ar(70%±3%)+СО2(30%±3%) in comparison with СО2(100%) enables to increase strength properties of the welded joint by 10-15% and enlarge the transitioncoefficient of chemical elements
Further investigations of the deep double donor magnesium in silicon
The deep double donor levels of substitutional chalcogen impurities in
silicon have unique optical properties which may enable a spin/photonic quantum
technology. The interstitial magnesium impurity (Mg) in silicon is also a
deep double donor but has not yet been studied in the same detail as have the
chalcogens. In this study we look at the neutral and singly ionized Mg
absorption spectra in natural silicon and isotopically enriched 28-silicon in
more detail. The 1s(A) to 1s(T) transitions, which are very strong for
the chalcogens and are central to the proposed spin/photonic quantum
technology, could not be detected. We observe the presence of another double
donor (Mg) that may result from Mg in a reduced symmetry
configuration, most likely due to complexing with another impurity. The neutral
species of Mg reveal unusual low lying ground state levels detected
through temperature dependence studies. We also observe a shallow donor which
we identify as a magnesium-boron pair
A Mg-pair isoelectronic bound exciton identified by its isotopic fingerprint in Si
We use the greatly improved optical linewidths provided by highly enriched
Si to study a photoluminescence line near 1017 meV previously observed
in the luminescence spectrum of natural Si diffused with Mg, and suggested to
result from the recombination of an isoelectronic bound exciton localized at a
Mg-pair center. In Si this no-phonon line is found to be comprised of
five components whose relative intensities closely match the relative
abundances of Mg-pairs formed by random combinations of the three stable
isotopes of Mg, thus confirming the Mg-pair hypothesis. We further present the
results of temperature dependence studies of this center that reveal unusual
and as yet unexplained behaviour.Comment: 5 pages, 4 figure
CD25 as a unique marker on human basophils in stable-mildly symptomatic allergic asthma.
BACKGROUND
Basophils in acute asthma exacerbation are activated as evidenced by their increased expression levels of activation markers such as CD203c and CD63. However, whether basophils of allergic asthmatics who are in stable phase and have no asthma exacerbations display a specific and distinctive phenotype from those of healthy individuals has yet to be well characterized.
OBJECTIVE
We aimed to identify the phenotype of basophils from allergic asthmatics in the stable phase and investigate whether such a phenotype is affected by ex vivo allergen stimulation.
METHODS
We determined by flow cytometry, the expression of surface proteins such as CD25, CD32, CD63, CD69, CD203c, and CD300a and intracellular anti-apoptotic proteins BCL-2, BCL-xL, and MCL-1. We investigated these markers in blood basophils obtained from well-characterized patients with stable-mildly symptomatic form of allergic asthma with no asthma exacerbation and from healthy individuals. Moreover, we determined ex vivo CD63, CD69, and CD25 on blood basophils from stable-mildly symptomatic allergic asthmatics upon allergen stimulation.
RESULTS
In contrast to all tested markers, CD25 was significantly increased on circulating basophils in the patient cohort with stable-mildly symptomatic allergic asthma than in healthy controls. The expression levels of CD25 on blood basophils showed a tendency to positively correlate with FeNO levels. Notably, CD25 expression was not affected by ex vivo allergen stimulation of blood basophils from stable-mildly symptomatic allergic asthma patients.
CONCLUSION
Our data identifies CD25 as a unique marker on blood basophils of the stable phase of allergic asthma but not of asthma exacerbation as mimicked by ex vivo allergen stimulation
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