86 research outputs found

    Histological and compositional responses of bone to immobilization and other experimental conditions

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    Histological techniques were utilized for evaluating progressive changes in tibial compact bone in adult male monkeys during chronic studies of immobilization-associated osteopenia. The animals were restrained in a semirecumbent position which reduces normally occurring stresses in the lower extremities and results in bone mass loss. The longest immobilization studies were of seven months duration. Losses of haversian bone tended to occur predominatly in the proximal tibia and were characterized by increased activation with excessive depth of penetration of osteoclastic activity. There was no apparent regulation of the size and orientation of resorption cavities. Rapid bone loss seen during 10 weeks of immobilization appeared to be due to unrestrained osteoclastic activity without controls and regulation which are characteristic of adaptive systems. The general pattern of loss persisted throughout 7 months of immobilization. Clear cut evidence of a formation phase in haversian bone was seen only after two months of reambulation

    High pressure study of BaFe2As2 - role of hydrostaticity and uniaxial stress

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    We investigate the evolution of the electrical resistivity of BaFe2As2 single crystals with pressure. The samples used were from the same batch grown from self flux and showed properties that were highly reproducible. Samples were pressurised using three different pressure media: pentane-isopentane (in a piston cylinder cell), Daphne oil (in an alumina anvil cell) and steatite (in a Bridgman cell). Each pressure medium has its own intrinsic level of hydrostaticity, which dramatically affects the phase diagram. An increasing uniaxial pressure component in this system quickly reduces spin density wave order and favours the appearance of superconductivity, similar to what is seen in SrFe2As2.Comment: 11 page

    On the Hidden Order in URu2_{2}Si2_{2} --- Antiferro Hexadecapole Order and its Consequences

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    An antiferro ordering of an electric hexadecapole moment is discussed as a promising candidate for the long standing mystery of the hidden order phase in URu2_{2}Si2_{2}. Based on localized ff-electron picture, we discuss the rationale of the selected multipole and the consequences of the antiferro hexadecapole order of xy(x2−y2)xy(x^{2}-y^{2}) symmetry. The mean-field solutions and the collective excitations from them explain reasonably significant experimental observations: the strong anisotropy in the magnetic susceptibility, characteristic behavior of pressure versus magnetic field or temperature phase diagrams, disappearance of inelastic neutron-scattering intensity out of the hidden order phase, and insensitiveness of the NQR frequency at Ru-sites upon ordering. A consistency with the strong anisotropy in the magnetic responses excludes all the multipoles in two-dimensional representations, such as (Oyz,Ozx)(O_{yz},O_{zx}). The expected azimuthal angle dependences of the resonant X-ray scattering amplitude are given. The (x2−y2)(x^{2}-y^{2})-type antiferro quadrupole should be induced by an in-plane magnetic field along [110][110], which is reflected in the thermal expansion and the elastic constant of the transverse (c11−c12)/2(c_{11}-c_{12})/2 mode. The (x2−y2)(x^{2}-y^{2})-type [(xy)(xy)-type] antiferro quadrupole is also induced by applying the uniaxial stress along [110][110] direction [[100][100] direction]. A detection of these induced antiferro quadrupoles under the in-plane magnetic field or the uniaxial stress using the resonant X-ray scattering provides a direct redundant test for the proposed order parameter.Comment: 10 pages, 10 figures, 5 table

    Details of Sample Dependence and Transport Properties of URu2Si2

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    Resistivity and specific heat measurements were performed in the low carrier unconventional superconductor URu2Si2 on various samples with very different qualities. The superconducting transition temperature (TSC) and the hidden order transition temperature (THO) of these crystals were evaluated as a function of the residual resistivity ratio (RRR). In high quality single crystals the resistivity does not seem to follow a T2 dependence above TSC, indicating that the Fermi liquid regime is restricted to low temperatures. However, an analysis of the isothermal longitudinal magnetoresistivity points out that the T2 dependence may be "spoiled" by residual inhomogeneous superconducting contribution. We discuss a possible scenario concerning the distribution of TSC related with the fact that the hidden order phase is very sensitive to the pressure inhomogeneity.Comment: 10 pages, 14 figures, accepted for publication in J. Phys. Soc. Jp

    Dual effect of oxidative stress on leukemia cancer induction and treatment

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