Vectores clave del desarrollo del marketing de personal: encontrando un equilibrio entre el marketing y la gestión de RRHH desde la perspectiva del modelado cognitivo

Human resources management remains an important area of modern enterprise strategy, as the role of personnel increases in high-tech production, and the highest requirements are placed on competencies. The goal of personnel-marketing is to influence the choice of profession and place of work. Labor carrier-the buyer evaluates and makes a decision about choosing a workplace depending on how much the workplace actualizes his ability to work and meets his expectations as an employee. Discussion. Note that the choice of a job occurs twice: when the candidate sends a resume to the company and when the candidate makes a decision after the interview. The development prospects of any enterprise are closely linked to existing market trends, knowledge of which helps to choose the appropriate strategy and directions for the development of competencies and the distribution of labor resources. Results. These circumstances actualize the study of the concept of personnel marketing, which is especially important in the context of increasing market uncertainty (sanctions, sanitary and epidemiological restrictions, etc.).La gestión de recursos humanos sigue siendo un área importante de la estrategia empresarial moderna, a medida que aumenta el papel del personal en la producción de alta tecnología y se imponen los requisitos más altos a las competencias. El objetivo del marketing de personal es influir en la elección de la profesión y el lugar de trabajo. Transportista de mano de obra: el comprador evalúa y toma una decisión sobre la elección de un lugar de trabajo en función de cuánto el lugar de trabajo actualiza su capacidad para trabajar y cumple con sus expectativas como empleado. Discusión. Tenga en cuenta que la elección de un trabajo se produce dos veces: cuando el candidato envía un currículum a la empresa y cuando el candidato toma una decisión después de la entrevista. Las perspectivas de desarrollo de cualquier empresa están estrechamente vinculadas a las tendencias del mercado existente, cuyo conocimiento ayuda a elegir la estrategia y las orientaciones adecuadas para el desarrollo de competencias y la distribución de los recursos laborales. Resultados. Estas circunstancias actualizan el estudio del concepto de marketing de personal, que es especialmente importante en un contexto de creciente incertidumbre del mercado (sanciones, restricciones sanitarias y epidemiológicas, etc.)

Power system for schoolchildren based on their genotypes

The article discusses a decision support system based on the clustering of genotypes and used in managing personalized nutrition for schoolchildren. The results of solving the problem for specific objects that have passed laboratory studies of gene states are presented. Modern scientific research in the field of nutrigenomics has shown that the selection of the optimal nutrition plan, taking into account genetic characteristics, increases the effectiveness of such programs by 200-300% compared with traditional approaches. This report discusses the use of soft computing (the method of clustering multidimensional objects) to determine typical clusters for managing personalized customer nutrition based on their genotypes

Некоторые аспекты нормирования загрязняющих веществ в почве

There are considered Russian and foreign valuation experience of pollutants in soils. Actuality of the topic is that the soil plays an important role in the natural habitat of human. First of all, the soil is the main means of agricultural production, referring to the category of non-renewable natural resources.Рассмотрен российский и зарубежный опыт нормирования загрязняющих веществ в почвах. Актуальность данной темы заключается в том, что почве принадлежит важная роль в природной среде обитания человека прежде всего потому, что почва - основное средство сельскохозяйственного производства, относящееся к категории возобновимых природных ресурсов

Research the phytoplankton dynamics regimes depending on nutrient transformation processes in coastal systems

The paper describes the construction of a three-dimensional mathematical model of biogeochemical processes, considering the salinity and temperature influence on the phytoplankton populations’ development. The paper proposes a new difference scheme for solving convection-diffusion-reaction problems at large values of the Peclet grid number (2<Pe≤20), which is a linear combination of the central and the upwind leapfrog difference schemes. The three-layer difference scheme is more accurate than the traditional upwind leapfrog difference scheme for problems where convection prevails over diffusion. The construction of discrete equations for solving the problem of biogeochemical cycles on the basis of the scheme considering the filling of cells is described. The stationary regimes of phytoplankton dynamics problem were researched considering the transformation of phosphorus, nitrogen and silicon forms. Results of software complex, which allows to simulate biogeochemical processes in the Azov Sea, were described. The software package allows to forecast the dynamics of the Azov Sea ecosystem development in the conditions of modern salinization.The reported study was funded by RFBR, project number 20-01-00421

Estimation of relative risk of development and informativeness of diagnostic methods of hyperproliferative processes of endometrium

The aim: To conduct a comparative analysis of the results of ultrasound and hysteroscopic examinations with further histopathological findings and the clinical and anamnestic features of patients with hyperproliferative pathology in order to determine the etiopathogenetic mechanisms of the development of endometrial pathological processes. Materials and methods: We studied 119 medical records of patients of the Gynecological Department of Minipal Non-Commercial Enterprise “Ternopil Municipal City Hospital No. 2”, who applied for medical assistance because of benign endometrial hyperplasia in the reproductive age with a verified diagnosis of “uterine polyp” during 2017–2018. The control group consisted of 30 patients of the same age group, with menstrual disorders with no signs of hyperplastic processes of endometrium. With the consent of the patients, they were treated with diagnostic hysteroscopy in order to study evacuated material from the uterus. The results of the histological study confirmed the absence of signs of hyperplastic processes of endometrium. The results of diagnostic methods were evaluated by comparing the material’s histological data with the results of ultrasound and hysteroresectoscopy. Results: Taking into account the results of our research, women with hyperplastic processes of endometrium have the risk of the pathology of the nervous system is in 2.71 times higher (OR=2.71, CI–0.88: 8.33), cardiovascular pathology—in 2.04 (OR=2.04, CI–0.57:7.34), vascular diseases of the lower extremities—in 1.81 times (OR=1.81, CI–0.21:15.32) compared with the control group. While the risk of pathology of the urinary system and organs of vision is only—OR=0.48, CI–0.11:2.03 and OR=0.75, CI–0.08:7.48, respectively. Analyzing the results of the study using ultrasound examination, it was found that endometrial polyposis in combination with uterine leiomyoma was not detected in 3 women (15%), while all the results of hysteroscopy were confirmed by histopathological studies. When the endometrial hyperplastic processes were combined with adenomyosis— according to ultrasound examination a false positive result was obtained in 2 patients (13.3%), and in a hysteroscopic study we determined –1 false positive result. In patients the diagnosis of “endometrial polyp” according to the results of hysteroscopy was not confirmed in 2 women (2 false positive results 2.99%) and in 5 cases of ultrasound examination (5 false negative results 7.46%). The use of ultrasound examinations in patients with endometrial hyperplastic changes, according to our data, made it possible to identify pathology in 88.39% of cases, while the information content of the hysteroscopy was 98.21% (p<0.001). Conclusions: Thus, the results of the subjective examination of patients in the gynecological department: complaints, anamnestic data on gynecological and extragenital pathology should be used to identify etiopathogenetic factors and the formation of risk groups for the occurrence of hyperplastic processes of endometrium. Women with cervical erosion, uterine myoma and episodes of herpetic rash on the mucous membranes in past medical history have a higher likelihood of hyperplastic processes of endometrium. The vast majority of patients (63.87%) with polyps of the body of the uterus have a combined hyperproliferative pathology, which requires an individual approach to planning the scope of diagnostic examination and the choice of treatment method. Visualization of endometrium with hysteroscopy is more informative than ultrasound for diagnosing hyperproliferative processes, including uterine polyps. Hysteroscopic polypectomy has a high level of both clinical and economic benefits as well as diagnostic value in patients with hyperplastic processes of endometrium

КЛИНИКО-ЭКСПЕРИМЕНАЛЬНЫЕ ИССЛЕДОВАНИЯ ИММУНОМОДУЛИРУЮЩЕГО ЭФФЕКТА АМИСУЛЬПРИДА

Study of immunomodulatory effect of atypical antipsychotic amisulpride has revealed a positive clinical effect after 6-week therapy of schizophrenic patients regarding both positive and negative symptoms. A decrease in activity of humoral immunity factors (В lymphocytes, immunoglobulins, HLA-DR+-cells) identified among schizophrenic patients in the process of amisulpride therapy can be attributed to a positive effect optimizing the ratio Th1/Th2. Amisulpride when used under experimental conditions produced a suppression of IgM-immune response in mice of the C57BL/6J strain. This effect was more expressed in animals with aggressive behavior pattern. Изучение иммуномодулирующего эффекта атипичного антипсихотика амисульприда в клинике продемонстрировало положительный клинический эффект в динамике 6-недельной терапии больных шизофренией в отношении как позитивной, так и негативной симптоматики. Установленное снижение активности факторов гуморального иммунитета (В лимфоцитов, иммуноглобулинов, клеток HLA-DR+) у больных шизофренией в процессе терапии амисульпридом можно отнести к благоприятному эффекту, оптимизирующему соотношение Т лимфоцитов-хелперов Tх1/Tх2. Использование амисульприда в экспериментальных условиях привело к угнетению IgM-иммунного ответа у мышей линии С57BL/6J, наиболее выраженное при проявлении у них агрессивного типа поведения.

Morphological changes of the endometrium in hyperplastic process in women of reproductive age

The aim: To conduct a morphological study of endometrial tissue to identify changes characteristic of viral lesions to develop improved antirelapse treatment of HPE in women of reproductive age. Materials and methods: We surveyed 90 patients of the gynecological department who sought medical for hyperplastic processes of the endometrium in reproductive age. All women underwent hysteroscopy, the resulting material was subjected to morphological examination. Results: It became known that the virus is involved in the pathogenesis of endometrial hyperplasia. It is likely that it exists in epitheliocytes not only as a “passenger”, but also as an etiological factor. It became known that it was in complex hyperplasia with atypia that the percentage reached the highest level, which is a precancerous condition. Conclusions: Typical morphological change of the endometrium – multinucleation, multinuclearity and koilocytotic atypia in women of childbearing age with HPE – was revealed. The presence of infectious pathogens in the endometrium of patients with HPE can be regarded as one of the possible triggers for the development of hyperplastic processes

The effectiveness of the use of the silicon-containing preparation Siliplant in the case of clonal micropropagation of the rose Reine Sammut

Clonal micropropagation of plants is a modern popular method of vegetative reproduction, which allows to obtain high-quality planting material in a large volume in a short time. The research is devoted to the technology of clonal micropropagation of the rose Reine Sammut, in particular, optimization of the nutrient medium composition. To increase the efficiency of micropropagation, the silicon-containing preparation Siliplant was added to the composition of the nutrient medium according to the Murashige-Skoog (MS) recipe as an alternative to the complex of trace elements. At the stage of the actual micropropagation with the combined use of 6-benzylaminopurine (6-BAP) at doses of 1.0; 2.0 and 3.0 mg/l and Siliplant at doses of 1.0; 2.0 and 3.0 ml/l, no large differences were found. Nevertheless, the inclusion of Siliplant (1.0 ml/l) and 6-BAP (3.0 mg/l) in the medium contributed to an increase in the reproduction factor by 3.1 pcs./cuttings at LSD05 = 1.0 pcs. In addition, Siliplant at a dose of 1.0 ml/l as part of a hormone-free nutrient medium MS contributed to a significant increase in shoot growth (by 4.2 mm at LSD05 = 3.6), and at a dose of 3.0 ml/l stimulated the development of standard micro-plants of roses

Intramolecular thermal and catalytic [4+2]-cycloaddition in 2-alkenylfurans

Data on the intramolecular Diels-Alder reaction in the 2-alkenylfuran series are generalised. The methods and conditions for the formation of tricyclic systems are considered. The effect of substituents in the furan and unsaturated fragments on the cycloaddition are discussed. The results of using this reaction for the synthesis of alkaloids and terpenoids are presented