16 research outputs found

    Vitamin D in health and disease: Current perspectives

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    Despite the numerous reports of the association of vitamin D with a spectrum of development, disease treatment and health maintenance, vitamin D deficiency is common. Originating in part from the diet but with a key source resulting from transformation by exposure to sunshine, a great deal of the population suffers from vitamin D deficiency especially during winter months. It is linked to the treatment and pathogenesis and/or progression of several disorders including cancer, hypertension, multiple sclerosis, rheumatoid arthritis, osteoporosis, muscle weakness and diabetes. This widespread deficiency of Vitamin D merits consideration of widespread policies including increasing awareness among the public and healthcare professionals

    ALIVE:a framework for flexible and adaptive service coordination

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    There is a large body of research on software services, but the issues of communication and dynamic reconfiguration have received little attention, as have adaptation to environment and dynamic combination of service building blocks into new applications. Here, we present the approach of the FP7 alive project to the use of formal models of coordination and organisation mechanisms to deliver a flexible, high-level means to describe the structure of interactions between services in the environment. Our aim is to create a framework for services engineering for “live” open systems of active services. We propose to build on the current activities in service-oriented engineering by defining three levels: (i) An organisational level models the organisational structure of executing and interlinked services and the context around them. (ii) A coordination level provides flexible ways to model interaction between the services. (iii) These two levels connect with existing (semantic) Web services, which contain semantic descriptions to make components aware of their social context and of the rules of engagement with other services

    Multiple sclerosis and vitamin D: an update

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