2,437 research outputs found
Ozone fumigation successfully controlled and eradicated multidrug-resistant Acinetobacter baumanii from an intensive care unit
Cette contribution porte sur la construction de savoirs professionnels dans l'alternance en formation initiale à l'enseignement. Elle postule que cette construction de savoirs se relie à l'émergence de l'identité professionnelle: le sujet en formation se construit comme acteur social en même temps des savoirs propices à son agir. Plus précisément, notre préoccupation de recherche concerne les indicateurs de cette co-construction soi/savoirs professionnels tels qu'on peut les inférer à partir de l'analyse de discours écrits ou oraux produits par les étudiants
Bjorken Flow, Plasma Instabilities, and Thermalization
At asymptotically high energies, thermalization in heavy ion collisions can
be described via weak-coupling QCD. We present a complete treatment of how
thermalization proceeds, at the parametric weak-coupling level. We show that
plasma instabilities dominate the dynamics, from immediately after the
collision until well after the plasma becomes nearly in equilibrium. Initially
they drive the system close to isotropy, but Bjorken expansion and increasing
diluteness makes the system again become more anisotropic. At time \tau ~
\alpha^(-12/5) Q^(-1) the dynamics become dominated by a nearly-thermal bath;
and at time \tau ~ \alpha^(-5/2) Q^(-1)$ the bath comes to dominate the energy
density, completing thermalization. After this time there is a nearly isotropic
and thermal Quark-Gluon Plasma.Comment: 22 pages, 5 figure
Thermalization in Weakly Coupled Nonabelian Plasmas
We investigate how relativistic, nonabelian plasmas approach equilibrium in a
general context. Our treatment is entirely parametric and for small Yang-Mills
coupling . First we study isotropic systems with an initially
nonequilibrium momentum distribution. We consider both the case of initially
very high occupancy and initially very low occupancy. Then we consider systems
which are anisotropic. We consider both weak anisotropy and large anisotropy,
and allow the occupancy to be parametrically large or small. Writing the
typical momentum of an initial excitation as Q and the final temperature as T,
full equilibration occurs in a time t ~ \alpha^{-2}/T for T > Q, and t ~
\alpha^{-2} Q^{1/2} T^{-3/2} for T < Q, unless the initial system is
sufficiently anisotropic and T > \alpha^{2/3} Q, in which case equilibration
occurs somewhat faster, t ~ \alpha^{-13/7} Q^{5/7} T^{-12/7} (or \alpha^{-2}/T
if that is longer).Comment: 55 pages including many figures, but with a comprehensive review of
results in the first 6 pages
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Crystal structures of Λ-[Ru(phen)2dppz]2+ with oligonucleotides containing TA/TA and AT/AT steps show two intercalation modes
The ruthenium complex [Ru(phen)2(dppz)] (where phen is a phenanthroline and dppz a dipyridyl–phenazine ligand) is
known as a ‘light switch’ complex because its luminescence in solution is significantly enhanced in the presence of DNA. This property is poised to serve in diagnostic and therapeutic applications, but its binding mode with DNA needs to be elucidated further. Here, we describe the crystal structures of the L enantiomer bound to two oligonucleotide duplexes. The dppz ligand intercalates symmetrically and perpendicularly from the minor groove of the d(CCGGTACCGG)2 duplex at the central TA/TA step, but not at the central AT/AT step of d(CCGGATCCGG)2. In both structures, however, a second ruthenium complex links the duplexes through the combination of a shallower angled intercalation into the C1C2/G9G10 step at the end of the duplex, and semi-intercalation into the G3G4 step of an adjacent duplex. The TA/TA specificity of the perpendicular intercalation arises from the packing of phenanthroline ligands against the adenosine residue
Modelling diverse root density dynamics and deep nitrogen uptake — a simple approach
We present a 2-D model for simulation of root density and plant nitrogen (N) uptake for crops grown in agricultural systems, based on a modification of the root density equation originally proposed by Gerwitz and Page in J Appl Ecol 11:773–781, (1974). A root system form parameter was introduced to describe the distribution of root length vertically and horizontally in the soil profile. The form parameter can vary from 0 where root density is evenly distributed through the soil profile, to 8 where practically all roots are found near the surface. The root model has other components describing root features, such as specific root length and plant N uptake kinetics. The same approach is used to distribute root length horizontally, allowing simulation of root growth and plant N uptake in row crops. The rooting depth penetration rate and depth distribution of root density were found to be the most important parameters controlling crop N uptake from deeper soil layers. The validity of the root distribution model was tested with field data for white cabbage, red beet, and leek. The model was able to simulate very different root distributions, but it was not able to simulate increasing root density with depth as seen in the experimental results for white cabbage. The model was able to simulate N depletion in different soil layers in two field studies. One included vegetable crops with very different rooting depths and the other compared effects of spring wheat and winter wheat. In both experiments variation in spring soil N availability and depth distribution was varied by the use of cover crops. This shows the model sensitivity to the form parameter value and the ability of the model to reproduce N depletion in soil layers. This work shows that the relatively simple root model developed, driven by degree days and simulated crop growth, can be used to simulate crop soil N uptake and depletion appropriately in low N input crop production systems, with a requirement of few measured parameters
Hepatitis C prevalence in Denmark in 2016—An updated estimate using multiple national registers
Background: Chronic hepatitis C (CHC) can be eliminated as a public health threat by meeting the WHO targets: 90% of patients diagnosed and 80% treated by 2030. To achieve and monitor progress towards elimination, an updated estimate of the size of the CHC population is needed, but Denmark has no complete national CHC register. By combining existing registers in 2007, we estimated the population living with CHC to be 16,888 (0.38% of the adult population).
Aim: To estimate the population living with diagnosed and undiagnosed CHC in Denmark on 31 December 2016. Among additional aims were to estimate the proportion of patients attending specialised clinical care.
Methods: People with diagnosed CHC were identified from four national registers. The total diagnosed population was estimated by capture-recapture analysis. The undiagnosed population was estimated by comparing the register data with data from two cross-sectional surveys.
Results: The population living with diagnosed CHC in Denmark was 7,581 persons (95%CI: 7,416–12,661) of which 6,116 (81%) were identified in the four registers. The estimated undiagnosed fraction was 24%, so the total CHC infected population was 9,975 corresponding to 0.21% of the adult population (95%CI: 9,758–16,659; 0.21%-0.36%). Only 48% of diagnosed patients had received specialised clinical care.
Conclusion: CHC prevalence in Denmark is declining and 76% of patients have been diagnosed. Linking diagnosed patients to care and increasing efforts to test people with former or current drug use will be necessary to achieve CHC elimination
Wave Intensity Analysis Provides Novel Insights Into Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension.
BACKGROUND: In contrast to systemic hypertension, the significance of arterial waves in pulmonary hypertension (PH) is not well understood. We hypothesized that arterial wave energy and wave reflection are augmented in PH and that wave behavior differs between patients with pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). METHODS AND RESULTS: Right heart catheterization was performed using a pressure and Doppler flow sensor-tipped catheter to obtain simultaneous pressure and flow velocity measurements in the pulmonary artery. Wave intensity analysis was subsequently applied to the acquired data. Ten control participants, 11 patients with PAH, and 10 patients with CTEPH were studied. Wave speed and wave power were significantly greater in PH patients compared with controls, indicating increased arterial stiffness and right ventricular work, respectively. The ratio of wave power to mean right ventricular power was lower in PAH patients than CTEPH patients and controls. Wave reflection index in PH patients (PAH: ≈25%; CTEPH: ≈30%) was significantly greater compared with controls (≈4%), indicating downstream vascular impedance mismatch. Although wave speed was significantly correlated to disease severity, wave reflection indexes of patients with mildly and severely elevated pulmonary pressures were similar. CONCLUSIONS: Wave reflection in the pulmonary artery increased in PH and was unrelated to severity, suggesting that vascular impedance mismatch occurs early in the development of pulmonary vascular disease. The lower wave power fraction in PAH compared with CTEPH indicates differences in the intrinsic and/or extrinsic ventricular load between the 2 diseases
Vortices on Orbifolds
The Abelian and non-Abelian vortices on orbifolds are investigated based on
the moduli matrix approach, which is a powerful method to deal with the BPS
equation. The moduli space and the vortex collision are discussed through the
moduli matrix as well as the regular space. It is also shown that a quiver
structure is found in the Kahler quotient, and a half of ADHM is obtained for
the vortex theory on the orbifolds as the case before orbifolding.Comment: 25 pages, 4 figures; references adde
The mineralocorticoid receptor antagonist eplerenone reduces renal interstitial fibrosis after long-term cyclosporine treatment in rat: antagonizing cyclosporine nephrotoxicity
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