A newly discovered stellar type: dusty post-red giant branch stars in the Magellanic Clouds

Context: We present a newly discovered class of low-luminosity, dusty, evolved objects in the Magellanic Clouds. These objects have dust excesses, stellar parameters, and spectral energy distributions similar to those of dusty post-asymptotic giant branch (post-AGB) stars. However, they have lower luminosities and hence lower masses. We suggest that they have evolved off the red giant branch (RGB) instead of the AGB as a result of binary interaction. Aims: In this study we aim to place these objects in an evolutionary context and establish an evolutionary connection between RGB binaries (such as the sequence E variables) and our new sample of objects. Methods: We compared the theoretically predicted birthrates of the progeny of RGB binaries to the observational birthrates of the new sample of objects. Results: We find that there is order-of-magnitude agreement between the observed and predicted birthrates of post-RGB stars. The sources of uncertainty in the birthrates are discussed; the most important sources are probably the observational incompleteness factor and the post-RGB evolution rates. We also note that mergers are relatively common low on the RGB and that stars low on the RGB with mid-IR excesses may recently have undergone a merger. Conclusions: Our sample of dusty post-RGB stars most likely provides the first observational evidence for a newly discovered phase in binary evolution: post-RGB binaries with circumstellar dust.Comment: Accepted for publication in Astronomy and Astrophysics Letter

Unsupervised learning for cross-domain medical image synthesis using deformation invariant cycle consistency networks

Recently, the cycle-consistent generative adversarial networks (CycleGAN) has been widely used for synthesis of multi-domain medical images. The domain-specific nonlinear deformations captured by CycleGAN make the synthesized images difficult to be used for some applications, for example, generating pseudo-CT for PET-MR attenuation correction. This paper presents a deformation-invariant CycleGAN (DicycleGAN) method using deformable convolutional layers and new cycle-consistency losses. Its robustness dealing with data that suffer from domain-specific nonlinear deformations has been evaluated through comparison experiments performed on a multi-sequence brain MR dataset and a multi-modality abdominal dataset. Our method has displayed its ability to generate synthesized data that is aligned with the source while maintaining a proper quality of signal compared to CycleGAN-generated data. The proposed model also obtained comparable performance with CycleGAN when data from the source and target domains are alignable through simple affine transformations

Oscillatory instability in a driven granular gas

We discovered an oscillatory instability in a system of inelastically colliding hard spheres, driven by two opposite "thermal" walls at zero gravity. The instability, predicted by a linear stability analysis of the equations of granular hydrodynamics, occurs when the inelasticity of particle collisions exceeds a critical value. Molecular dynamic simulations support the theory and show a stripe-shaped cluster moving back and forth in the middle of the box away from the driving walls. The oscillations are irregular but have a single dominating frequency that is close to the frequency at the instability onset, predicted from hydrodynamics.Comment: 7 pages, 4 figures, to appear in Europhysics Letter

Quantum monitoring of cellular metabolic activities in single mitochondria

Free radicals play a vital role in all kinds of biological processes including immune responses. However, free radicals have short lifetimes and are highly reactive, making them difficult to measure using current methods. Here, we demonstrate that relaxometry measurement, or T1, inherited from the field of diamond magnetometry can be used to detect free radicals in living cells with subcellular resolution. This quantum sensing technique is based on defects in diamond, which convert a magnetic signal into an optical signal, allowing nanoscale magnetic resonance measurements. We functionalized fluorescent nanodiamonds (FNDs) to target single mitochondria within macrophage cells to detect the metabolic activity. In addition, we performed measurements on single isolated mitochondria. We were able to detect free radicals generated by individual mitochondria in either living cells or isolated mitochondria after stimulation or inhibition

Regulation of Calcium-Permeable TRPV2 Channel by Insulin in Pancreatic β-Cells

OBJECTIVE—Calcium-permeable cation channel TRPV2 is expressed in pancreatic β-cells. We investigated regulation and function of TRPV2 in β-cells

The rms-flux relations in different branches in Cyg X-2

In this paper, the rms-flux (root mean square-flux) relation along the Z-track of the bright Z-Source Cyg X-2 is analyzed using the observational data of Rossi X-ray Timing Explorer (RXTE). Three types of rms-flux relations, i.e. positive, negative, and 'arch'-like correlations are found in different branches. The rms is positively correlated with flux in normal branch (NB), but anti-correlated in the vertical horizontal branch (VHB). The rms-flux relation shows an 'arch'-like shape in the horizontal branch (HB). We also try to explain this phenomenon using existing models.Comment: Accepted for publication in Astrophysics & Space Scienc

h→μτh\to \mu\tau at Hadron Colliders

We study the observability for a lepton flavor-changing decay of a Higgs boson $h\to \mu\tau$ at hadron colliders. Flavor-changing couplings of a Higgs boson exist at tree level in models with multiple Higgs doublets. The $h\mu\tau$ coupling is particularly motivated by the favorable intepretation of $\nu_\mu-\nu_\tau$ oscillation. We find that at the Tevatron Run II the unique $\mu\tau$ signature could serve as the Higgs discovery channel, surpassing expectations for Higgs boson searches in the SM and in a large parameter region of the MSSM. The sensitivity will be greatly improved at the LHC, beyond the coverage at a muon collider Higgs factory.Comment: Version to appear in PR

Delineating Electrogenic Reactions during Lactose/H+ Symport†

Electrogenic reactions accompanying downhill lactose/H+ symport catalyzed by the lactose permease of Escherichia coli (LacY) have been assessed using solid-supported membrane-based electrophysiology with improved time resolution. Rates of charge translocation generated by purified LacY reconstituted into proteoliposomes were analyzed over a pH range from 5.2 to 8.5, which allows characterization of two electrogenic steps in the transport mechanism: (i) a weak electrogenic reaction triggered by sugar binding and observed under conditions where H+ translocation is abolished either by acidic pH or by a Glu325 -> Ala mutation in the H+ binding site (this step with a rate constant of ~200 s-1 for wildtype LacY leads to an intermediate proposed to represent an “occluded” state) and (ii) a major electrogenic reaction corresponding to 94% of the total charge translocated at pH 8, which is pH-dependent with a maximum rate of ~30 s-1 and a pK of 7.5. This partial reaction is assigned to rate-limiting H+ release on the cytoplasmic side of LacY during turnover. These findings together with previous electrophysiological results and biochemical-biophysical studies are included in an overall kinetic mechanism that allows delineation of the electrogenic steps in the reaction pathway

Signature of multilayer growth of 2D layered Bi2Se3 through heteroatom-assisted step-edge barrier reduction

During growth of two-dimensional (2D) materials, abrupt growth of multilayers is practically unavoidable even in the case of well-controlled growth. In epitaxial growth of a quintuple-layered Bi2Se3 film, we observe that the multilayer growth pattern deduced from in situ x-ray diffraction implies nontrivial interlayer diffusion process. Here we find that an intriguing diffusion process occurs at step edges where a slowly downward-diffusing Se adatom having a high step-edge barrier interacts with a Bi adatom pre-existing at step edges. The Se???Bi interaction lowers the high step-edge barrier of Se adatoms. This drastic reduction of the overall step-edge barrier and hence increased interlayer diffusion modifies the overall growth significantly. Thus, a step-edge barrier reduction mechanism assisted by hetero adatom???adatom interaction could be fairly general in multilayer growth of 2D heteroatomic materials