Chronic disease management in Sub-Saharan Africa: whose business is it?

Public health specialists and clinicians alike agree that Humanity faces a global pandemic of chronic diseases in the 21(st) century. In this article we discuss the implications of this pandemic on another global issue, the health workforce. Because both issues are particularly acute in Sub-Saharan Africa (SSA), we will focus on this region and use Cameroon as a case in point. We first gauge the epidemic of chronic conditions in SSA. We then discuss the implications of chronic conditions for the reshaping of health systems and the health workforce. We conclude by making a strong case for the building up and strengthening the health workforce, insisting on the crucial role of nurses, their training, and involvement in chronic disease management

Formation interprofessionnelle: une exigence pour une approche intégrée des soins?

The aging of the population and the rising prevalence of chronic diseases mandate improved collaboration among different health professionals. Interprofessional training is one way to improve it, because it encourages health professionals to learn with, from and about one another and respects the integrity and contribution of each profession. Few medical or health professional schools develop such dimensions in their curricula, while postgraduate and continuous training seldom offer such opportunities. Institutional and political commitment may significantly contribute to the development of such dimensions in medical and other health profession education. Having a same mission, sharing responsibility for the team success, defining clear member roles and task, and communicating on a routine basis represent other key factors of success

Biomechanics of keratoconus: Two numerical studies

International audienceBackground The steep cornea in keratoconus can greatly impair eyesight. The etiology of keratoconus remains unclear but early injury that weakens the corneal stromal architecture has been implicated. To explore keratoconus mechanics, we conducted two numerical simulation studies. Methods A finite-element model describing the five corneal layers and the heterogeneous mechanical behaviors of the ground substance and lamellar collagen-fiber architecture in the anterior and posterior stroma was developed using the Holzapfel-Gasser-Ogden constitutive model. The geometry was from a healthy subject. Its stroma was divided into anterior, middle, and posterior layers to assess the effect of changing regional mechanical parameters on corneal displacement and maximum principal stress under intraocular pressure. Specifically, the effect of softening an inferocentral corneal button, the collagen-based tissues throughout the whole cornea, or specific stromal layers in the button was examined. The effect of simply disorganizing the orthogonally-oriented posterior stromal fibers in the button was also assessed. The healthy cornea was also subjected to eye rubbing-like loading to identify the corneal layer(s) that experienced the most tensional stress. Results Conical deformation and corneal thinning emerged when the corneal button or the mid-posterior stroma of the button underwent gradual softening or when the collagen fibers in the mid-posterior stroma of the button were dispersed. Softening the anterior layers of the button or the whole cornea did not evoke conical deformation. Button softening greatly increased and disrupted the stress on Bowman’s membrane while mid-posterior stromal softening increased stress in the anterior layers. Eye rubbing profoundly stressed the deep posterior stroma while other layers were negligibly affected. Discussion These observations suggest that keratoconus could be initiated, at least partly, by mechanical instability/damage in the mid-posterior stroma that then imposes stress on the anterior layers. This may explain why subclinical keratoconus is marked by posterior but not anterior elevation on videokeratoscopy

The impact of chronic disease management on primary care doctors in Switzerland: a qualitative study

Abstract Background Patient-centeredness and therapeutic relationship are widely explored as a means to address the challenge of chronic disease and multi-morbidity management, however research focusing on the perspective of doctors is still rare. In this study, we aimed to explore the impact of the patient’s chronic disease(s) on their healthcare provider. Methods A qualitative approach was taken using semi-structured interviews with general practitioners working in outpatient clinics either in individual practices or in a hospital setting in Geneva, Switzerland. Codes were developed through an iterative process and using grounded theory an inductive coding scheme was performed to identify the key themes. Throughout the analysis process the research team reviewed the analysis and refined the coding scheme. Results Twenty interviews, 10 in each practice type, allowed for saturation to be reached. The following themes relevant to the impact of managing chronic diseases emerge around the issue of feeling powerless as a doctor; facing the patient’s socio-economic context; guidelines versus the reality of the patient; time; and taking on the patient’s burden. Primary care practitioners face an emotional burden linked with their powerlessness and work conditions, but also with the empathetic bond with their patients and their circumstances. Doctors seem poorly prepared for this emotional strain. The health system is also not facilitating this with time constraints and guidelines unsuitable for the patient’s reality. Conclusions Chronic disease and multi-morbidity management is a challenge for healthcare providers. This has its roots in patient characteristics, the overall health system and healthcare providers themselves. Structural changes need to be implemented at different levels: medical education; health systems; adapted guidelines; leading to an overall environment that favors the development of the therapeutic relationship

Prise en charge de l’insuffisance cardiaque chronique - Nouveautés et implications pour le médecin de premier recours

The latest recommendations of the European Society of Cardiology on chronic heart failure published in 2021 propose several new concepts. The main changes include a revision of the classification but most importantly modifications in the therapeutic management, especially concerning the first-line treatment of heart failure with reduced ejection fraction. Since heart failure affects approximately 2% of the general population, these new recommendations will have a definite impact on the practice of primary care physicians. Integrating these changes into heart failure management is essential to improve the prognosis, symptoms and the quality of life of patients. This article presents the most significant changes and their implications for primary care physicians.Les recommandations de la Société européenne de cardiologie sur l’insuffisance cardiaque chronique, parues en 2021, proposent plusieurs nouveaux concepts. On relève comme changements principaux une révision de la classification ainsi que des modifications dans la prise en charge thérapeutique, notamment concernant le traitement de première ligne de l’insuffisance cardiaque (IC) à fraction d’éjection réduite. L’IC touchant environ 2% de la population générale, ces nouvelles recommandations auront un impact certain sur la pratique clinique des médecins de premier recours. Intégrer ces nouveautés dans la prise en charge est essentiel afin d’améliorer le pronostic, les symptômes et la qualité de vie des patients. Cet article présente ces modifications majeures et leurs implications pour la pratique de premiers recours

Identification du patient complexe pour une prise en charge interprofessionnelle

La prise en charge des malades se complexifie, notamment en raison de l’augmentation de la prévalence des pathologies chroniques, des problématiques psychosociales et du vieillissement de la population.1 En effet, le patient qui cumule des problématiques de santé, sociales et environnementales voit celles-ci s’entremêler et inter agir les unes avec les autres pour créer une situation difficilement gérable. Ce nouvel état imprévu est appelé une propriété émergente, caractéristique des systèmes complexes.2,3 Par ailleurs, les guides de pratique basés sur les évidences sont élaborés pour une maladie spécifique et ne s’appliquent pas pour les patients avec plusieurs problèmes simultanés.4,5 Dans une publication de 2005, une modélisation de patients avec plusieurs maladies chroniques montre que les recommandations basées sur les preuves, pertinentes si elles s’appliquent à une maladie, perdent leur cohérence lorsqu’on doit les appliquer à un patient multimorbide

Urticaire : nouveautés et chronicité

Urticaria is a frequent disease and exist in an acute or chronic form. The pathophysiology, focused on mast cells and histamine among other mediators, is an active research field but still poorly understood. The medical care focus on the avoidance of triggers and aggravating factors. The recommended drug therapy has not changed. The acknowledgment of chronic urticaria as a chronic disease is essential according to the last international recommendations. Acknowledging the disease morbidity and consequences, in a private, social or professional environment, allows better medical care for patients. The latter should get support on the long term, thanks to multiple diagnostic and therapeutic guidance tools.L’urticaire est une maladie fréquente pouvant être aiguë ou chronique. Sa physiopathologie, centrée sur les mastocytes et de multiples médiateurs dont l’histamine, fait l’objet de nombreuses recherches mais reste encore mal connue. La prise en charge se concentre sur l’éviction des facteurs déclencheurs et aggravants. Les traitements médicamenteux recommandés n’ont pas changé. La reconnaissance de l’urticaire chronique en tant que maladie chronique est centrale dans les dernières recommandations internationales. La reconnaissance de la morbidité et des conséquences de la maladie, dans les cadres privé, social ou professionnel, permet une meilleure prise en charge des patient-es. Ces dernier-ères devront être accompagné-e-s sur le long terme, grâce à plusieurs outils diagnostiques et d’accompagnement thérapeutique

Partnerships in global health and collaborative governance: lessons learnt from the Division of Tropical and Humanitarian Medicine at the Geneva University Hospitals

BACKGROUND: In 2007 the “Crisp Report” on international partnerships increased interest in Northern countries on the way their links with Southern partners operated. Since its establishment in 2007 the Division of Tropical and Humanitarian Medicine at the Geneva University Hospitals has developed a variety of partnerships. Frameworks to assess these partnerships are needed and recent attention in the field of public management on collaborative governance may provide a useful approach for analyzing international collaborations. METHODS: Projects of the Division of Tropical and Humanitarian Medicine were analyzed by collaborators within the Division using the model proposed by Emerson and colleagues for collaborative governance, which comprises different components that assess the collaborative process. RESULTS: International projects within the Division of Tropical and Humanitarian Medicine can be divided into four categories: Human resource development; Humanitarian response; Neglected Tropical Diseases and Noncommunicable diseases. For each of these projects there was a clear leader from the Division of Tropical and Humanitarian Medicine as well as a local counterpart. These individuals were seen as leaders both due to their role in establishing the collaboration as well as their technical expertise. Across these projects the actual partners vary greatly. This diversity means a wide range of contributions to the collaboration, but also complexity in managing different interests. A common definition of the collaborative aims in each of the projects is both a formal and informal process. Legal, financial and administrative aspects of the collaboration are the formal elements. These can be a challenge based on different administrative requirements. Friendship is part of the informal aspects and helps contribute to a relationship that is not exclusively professional. CONCLUSION: Using collaborative governance allows the complexity of managing partnerships to be presented. The framework used highlights the process of establishing collaborations, which is an element often negated by other more traditional models used in international partnerships. Applying the framework to the projects of the Division of Tropical and Humanitarian Medicine highlights the importance of shared values and interests, credibility of partners, formal and informal methods of management as well as friendship