Soft tissue healing outcomes in dentistry with acellular dermal collagen matrix

Background and objectives: The collagen matrices are widely used for regeneration procedures alone or in combination with other dental regeneration materials. The aim of this work was to evaluate the soft tissue healing with acellular dermal collagen matrix (ADCM) being used in various defects. Materials and Methods: The ADCM - mucoderm® was used in peri-implant soft tissue augmentation, hard and soft tissue management in immediate restoration and sealing of extraction socket. For that reason, five patients were retrospectively analysed. Results: The collagen matrix underwent active remodelling into new soft tissue and successful soft tissue healing was observed. Conclusion: The use of mucoderm® led to successful soft tissue treatment in various defects

Chirurgia Robotica del Cancro del Colon Destro: Curva di Apprendimento ed Analisi dei Costi

Al giorno d'oggi, i pazienti richiedono senpre più di frequente un approccio chirurgico mini-invasivo, anche se solo una piccola percentuale di essi sembra avere accesso a questa chirurgia. I chirurghi, da parte loro, devono adattarsi agli sviluppi della tecnica chirurgica, soprattutto alla ridotta manovrabilità in campo operatorio e alla perdita della visione diretta. La curva di apprendimento delle procedure laparoscopiche o robotiche può essere lunga e difficile. La chirurgia robotica rappresenta la tecnologia più avanzata nel campo degli approcci minimamente invasivi. Questo lavoro prende in esame le caratteristiche generali, i vantaggi e gli svantaggi di queste tecniche chirurgiche, oltre a presentare i risultati di uno studio prospettico condotto per confrontare la curva di apprendimento del chirurgo e i costi socio-sanitari della colectomia destra eseguita per via laparoscopica o robotica. I risultati presentati in questa tesi dimostrano che le procedure laparoscopiche e robotiche hanno risultati operatori e postoperatori simili. La colectomia robotica destra sembra però avere una curva di apprendimento più veloce della laparoscopia. Per quanto riguarda i costi, una volta inclusi sia i costi operatori che la degenza ospedaliera, la laparoscopia e la chirurgia robotica sono associati a costi equivalenti. Ulteriori studi clinici sono necessari per rispondere alla domanda se l'approccio robotico potrebbe aumentare, grazie alla sua tecnologia avanzata, l'attuale bassa percentuale di pazienti sottoposti a chirurgia mini-invasiva

Preface [Special issue on Modeling and Simulation of Tumor Development, Treatment and Control]

Preface of the Special Issue: Modeling and Simulation of Tumor Development, Treatment, and Control, Edited by Nicola Bellomo and Elena De Angelis, Volume 37, Issue 11, Pages 1121-1252, 2003, Mathematical and Computer Modelling, ISSN 0895-7177, ELSEVIE

Evaluation of primary stability of single implants placed in fresh extraction sockets: a clinical trial

ABSTRACTDental implants have been used for the last 20 years. With the latest modern developments, however, minimally invasive protocols and immediate implants are currently used. The aim of this study was to evaluate the primary stability of a new implant design. Thirty immediate implants were placed and they all achieved successful osseointegration. Primary stability was reached with all the implants after the first apical threads. Within the limitations of the present study, the immediate implant approach seems to be a predictable treatment option, especially in conjunction with a specifically designed implant system

Malignant ventricular arrhythmias induction by programmed electrical stimulation of the right ventricular outflow tract only during type 1 brugada ECG maximization

OBJECTIVE: The role of electrophysiology study in Brugada syndrome (BS) sudden cardiac death risk stratification remains controversial and seems to depend on the phenotypic expression of the channelopathy. Ajmaline has a key role in the diagnosis of BS. We observed that programmed electrical stimulation (PES) of the right ventricular outflow tract (RVOT), only when type 1 BS ECG is unmasked by ajmaline administration, induces ventricular arrhythmias. CASE REPORT: We describe a case of ventricular fibrillation induction by PES of the RVOT when type 1 BS ECG is revealed by ajmaline, in a patient with a baseline dynamic intermittent type 1 and 2 BS ECG. CONCLUSIONS: The heterogeneous clinical presentations of BS are due to the underlying mechanisms. PES of the RVOT during positive ajmaline test maximizes the channelopathy and therefore sudden cardiac death risk-stratification in BS

Effectiveness of dual-wavelength (Diodes 980 Nm and 635 Nm) laser approach as a non-surgical modality in the management of periodontally diseased root surface: a pilot study

Conventional periodontal therapies have been widely discussed in the literature. The results of these therapies, surgically and non-surgically, have demonstrated high predictability and stable maintenance over time. With some clinical indications, such as inflamed sites with consistent bleeding on probing (BOP), it can be challenging for the root planning procedure to achieve predictable outcomes. Therefore, the aim and objectives of the present study were to evaluate whether the dual-wavelength (980 and 635 nm) laser therapy at lower power settings can be beneficial as a combined non-invasive modality in the management of periodontally diseased root surface in terms of improving the periodontal parameters. Thirty-five healthy patients were enrolled in this study. All patients had at least one pocket in the anterior and posterior teeth with initial periodontal pocket depth (PPD) > 6 mm associated with evidence of clinical inflammation, i.e. bleeding on probing (BOP++ or BOP+++) with no gingival recession. The treatment protocol utilized combined therapy of conventional debridement immediately followed by application of dual-wavelength laser therapy (photo-ablation and photodynamic therapies) at lower power settings. The results showed that all the pockets of involved teeth had an average gain of 3 mm of the clinical attachment level with no sign of BOP and reduction in the mobility of the teeth 35 days post-operatively. Thus, the utilization of the dual-wavelength approach of laser-assisted therapy at lower power settings appears to provide a promising and predictable non-invasive clinical approach in the management of compromised periodontally involved teeth

Amorphous silicon photosensors integrated in microfluidic structures as a technological demonstrator of a "true" Lab-on-Chip system

In this paper we present a compact technological demonstrator including on the same glass substrate an electrowetting-on-dielectrics (EWOD) system, a linear array of amorphous silicon photosensor and a capillary-driven microfluidic channel. The proposed system comprises also a compact modular electronics controlling the digital microfluidics through the USB interface of a computer. The system provides therefore both on-chip detection and microfluidic handling needed for the realization of a 'true' Lab-on-Chip. The geometry of the photosensors has been designed to maximize the radiation impinging on the photosensor and to minimize the inter-site crosstalk, while the fabrication process has been optimized taking into account the compatibility of all the technological steps for the fabrication of the EWOD system, the photosensor array and the microfluidics channels. As a proof of the successful integration of the different technological steps we demonstrated the ability of the a-Si:H photosensors to detect the presence of a droplet over an EWOD electrode and the effective coupling between the digital and the continuous microfluidics, that can allow for functionalization, immobilization and recognition of biomolecules without external optical devices or microfluidic interconnections