424 research outputs found

    PPS im IT-Servicemanagement: Möglichkeiten und Grenzen für die Provisionierung standardisierter Services

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    Zusammenfassung: Steigender Kostendruck und zunehmende Dienstleistungsorientierung erfordern ein Umdenken beim Einsatz von Methoden zum Management der Provisionierung von IT-Services. Wurden in der Vergangenheit primär Projektmanagementmethoden genutzt, rücken mit zunehmender Servicestandardisierung Methoden aus der Sachgüterfertigung in den Mittelpunkt. Im Beitrag wird dargestellt, welche Möglichkeiten und Grenzen industrielle Produktionsplanungsund -steuerungssysteme (PPS-Systeme) für die Provisionierung von IT-Services aufweisen. Das Beispiel der Global Delivery Unit SAP Services der T-Systems Enterprise Services GmbH veranschaulicht die Anwendung eines PPS-Systems im IT-Servicemanagemen

    A Service Model for the Development of Management Systems for IT-enabled Services

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    The shift from device and application towards service-orientated IT Management raises new questions that require concepts such as portfolio management, resource planning or mass customization for IT services. These concepts increase the complexity of IT Service Management and require additional tool support. Conceptual models are necessary in order to develop appropriate tools. The goal of our paper is to propose and validate a conceptual IT service model. We introduce the characteristics of IT services and analyze existing IT service models. A common IT service model is derived (theoretically) from the literature and validated through cases of IT service providers. These case studies from three German IT service providers also yield insights for further research

    Seed-mediated synthesis of gold nanorods: control of the aspect ratio by variation of the reducing agent

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    Seed-mediated growth methods involving reduction of tetrachloroaurate(III) with ascorbic acid are common for the synthesis of gold nanorods. This study shows, however, that simply by appropriate choice of the reducing agent a drastic influence on the aspect ratio can be attained. Weaker reducing agents, such as dihydroxybenzene isomers (hydroquinone, catechol or resorcinol) or glucose can increase the aspect ratio of the nanorods by an order of magnitude, up to values as high as 100 (nanowires). The increase in aspect ratio is mainly a consequence of an increase in length of the particles (up to 1-3μm). This effect is probably associated with a decrease in the reduction rate of gold(III) species by dihydroxybenzenes or glucose compared to ascorbic acid. The reduction potential of the reducing agents strongly depends on the pH value, and related effects on the dimensions of the nanoparticles are also reflected in this study. The nanorods exhibited penta-twinned nature without noteworthy defects (e.g. stacking faults and dislocations

    Long-lasting cross-protection against influenza A by neuraminidase and M2e-based immunization strategies

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    There is mounting evidence that in the absence of neutralizing antibodies cross-reactive T cells provide protection against pandemic influenza viruses. Here, we compared protection and CD8+ T cell responses following challenge with H1N1 2009 pandemic and H3N2 viruses of mice that had been immunized with hemagglutinin (HA), neuraminidase (NA) and the extracellular domain of matrix protein 2 (M2e) fused to a virus-like particle (VLP). Mice were challenged a first time with a sublethal dose of H1N1 2009 pandemic virus and, four weeks later, challenged again with an H3N2 virus. Mice that had been vaccinated with HA, NA, NA + M2e-VLP and HA + NA + M2e-VLP were protected against homologous H1N1 virus challenge. Challenged NA and NA + M2e-VLP vaccinated mice mounted CD8+ T cell responses that correlated with protection against secondary H3N2 challenge. HA-vaccinated mice were fully protected against challenge with homologous H1N1 2009 virus, failed to mount cross-reactive CD8+ T cells and succumbed to the second challenge with heterologous H3N2 virus. In summary, NA- and M2e-based immunity can protect against challenge with (homologous) virus without compromising the induction of robust cross-reactive CD8+ T cell responses upon exposure to virus

    Origin and spatial-temporal distribution of faecal bacteria in a bay of Lake Geneva, Switzerland

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    The origin and distribution of microbial contamination in Lake Geneva's most polluted bay were assessed using faecal indicator bacteria (FIB). The lake is used as drinking water, for recreation and fishing. During 1year, water samples were taken at 23 points in the bay and three contamination sources: a wastewater treatment plant (WWTP), a river and a storm water outlet. Analyses included Escherichia coli, enterococci (ENT), total coliforms (TC), and heterotrophic plate counts (HPC). E. coli input flux rates from the WWTP can reach 2.5 × 1010CFU/s; those from the river are one to three orders of magnitude lower. Different pathogenic Salmonella serotypes were identified in water from these sources. FIB levels in the bay are highly variable. Results demonstrate that (1) the WWTP outlet at 30m depth impacts near-surface water quality during holomixis in winter; (2) when the lake is stratified, the effluent water is generally trapped below the thermocline; (3) during major floods, upwelling across the thermocline may occur; (4) the river permanently contributes to contamination, mainly near the river mouth and during floods, when the storm water outlet contributes additionally; (5) the lowest FIB levels in the near-surface water occur during low-flow periods in the bathing seaso
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