The Civil Law of Quebec: Some Disjointed Notes for a Lecture

Quebec private law, though not the public law, can be regarded as a reasonably characteristic example of that system of law known as the Civil Law, one of the world\u27s great legal systems; and you live in the province of Prince Edward Island and I of Nova Scotia, where another of the world\u27s great systems flourishes, the Common Law - you will notice that I say another , not the other . It is right and proper that we should attempt to familiarize ourselves with at least one other system of law besides our own, not necessarily with the detailed rules, which may or may not differ from ours, but with the approach of that other system to human problems, its method. For there is no better avenue to improved knowledge of other peoples than through their law, and no one can deny that a better understanding of French Canada in other parts of our country is badly needed

Learning together: Lessons from a collaborative curriculum design project

Based on an action research project implemented at two South African universities, we argue that content and language integration (ICL) collaborative partnerships benefit not only from collaboration between language and content specialists, but in addition, from collaboration between language specialists, general education specialists and content specialists from a variety of disciplines. However, as we illustrate below, these benefits may be accompanied by substantial challenges. We make a further claim, for the value of a transformative approach towards collaboration for content and language integration, in which the teacher/researchers engage in their practice in a critical and reflexive manner, and by so doing, foster their own deep learning, as well as the deep learning of the students

Machine learning -- based diffractive imaging with subwavelength resolution

Far-field characterization of small objects is severely constrained by the diffraction limit. Existing tools achieving sub-diffraction resolution often utilize point-by-point image reconstruction via scanning or labelling. Here, we present a new imaging technique capable of fast and accurate characterization of two-dimensional structures with at least wavelength/25 resolution, based on a single far-field intensity measurement. Experimentally, we realized this technique resolving the smallest-available to us 180-nm-scale features with 532-nm laser light. A comprehensive analysis of machine learning algorithms was performed to gain insight into the learning process and to understand the flow of subwavelength information through the system. Image parameterization, suitable for diffractive configurations and highly tolerant to random noise was developed. The proposed technique can be applied to new characterization tools with high spatial resolution, fast data acquisition, and artificial intelligence, such as high-speed nanoscale metrology and quality control, and can be further developed to high-resolution spectroscop

Phase-sensitive FMCW radar system for high-precision Antarctic ice shelf profile monitoring

Ice shelves fringe much of the Antarctic continent, and, despite being up to 2 km thick, are vulnerable to climate change. Owing to their role in helping to control the ice sheet contribution to sea level change there is great interest in measuring the rate at which they are melting into the ocean. This study describes the development and deployment of an ice-penetrating phase-sensitive FMCW radar, sufficiently robust and with sufficiently low-power consumption to be run through the Antarctic winter as a standalone instrument, yet with the stability and mm-precision needed to detect the very slow changes in ice shelf thickness in this exceptionally demanding environment. A number of elegant processing techniques are described to achieve reliable, high-precision performance and results presented on field data obtained from the Larsen-C ice shelf, Antarctica

Andreev Probe of Persistent Current States in Superconducting Quantum Circuits

Using the extraordinary sensitivity of Andreev interferometers to the superconducting phase difference associated with currents, we measure the persistent current quantum states in superconducting loops interrupted by Josephson junctions. Straightforward electrical resistance measurements of the interferometers give continuous read-out of the states, allowing us to construct the energy spectrum of the quantum circuit. The probe is estimated to be more precise and faster than previous methods, and can measure the local phase difference in a wide range of superconducting circuits.Comment: Changes made in light of referees comments; to appear in PR

Diffusion-controlled generation of a proton-motive force across a biomembrane

Respiration in bacteria involves a sequence of energetically-coupled electron and proton transfers creating an electrochemical gradient of protons (a proton-motive force) across the inner bacterial membrane. With a simple kinetic model we analyze a redox loop mechanism of proton-motive force generation mediated by a molecular shuttle diffusing inside the membrane. This model, which includes six electron-binding and two proton-binding sites, reflects the main features of nitrate respiration in E. coli bacteria. We describe the time evolution of the proton translocation process. We find that the electron-proton electrostatic coupling on the shuttle plays a significant role in the process of energy conversion between electron and proton components. We determine the conditions where the redox loop mechanism is able to translocate protons against the transmembrane voltage gradient above 200 mV with a thermodynamic efficiency of about 37%, in the physiologically important range of temperatures from 250 to 350 K.Comment: 26 pages, 4 figures. A similar model is used in arXiv:0806.3233 for a different biological system. Minor changes in the Acknowledgements sectio

Review of eating disorders and oxytocin receptor polymorphisms.

BACKGROUND AND AIMS: Oxytocin, a nine amino acid peptide synthesised in the hypothalamus, has been widely recognised for its role in anxiolysis, bonding, sociality, and appetite. It binds to the oxytocin receptor (OXTR)-a G-protein coupled receptor-that is stimulated by the actions of oestrogen both peripherally and centrally. Studies have implicated OXTR genotypes in conferring either a risk or protective effect in autism, schizophrenia, and eating disorders (ED). There are numerous DNA variations of this receptor, with the most common DNA variation being in the form of the single nucleotide polymorphisms (SNPs). Two OXTR SNPs have been most studied in relation to ED: rs53576 and rs2254298. Each SNP has the same allelic variant that produces genotypes AA, AG, and GG. In this critical review we will evaluate the putative role of rs53576 and rs2254298 SNPs in ED. Additionally, this narrative review will consider the role of gene-environment interactions in the development of ED pathology. FINDINGS: The OXTR SNPs rs53576 and rs2254298 show independent associations between the A allele and restrictive eating behaviours. Conversely, the G allele of the OXTR rs53576 SNP is associated with binging behaviours, findings that were also evident in neuroanatomy. One study found the A allele of both OXTR SNPs to confer risk for more severe ED symptomatology while the G allele conferred some protective effect. An interaction between poor maternal care and rs2254298 AG/AA genotype conferred increased risk for binge eating and purging in women. CONCLUSIONS: Individual OXTR SNP are unlikely in themselves to explain complex eating disorders but may affect the expression of and/or effectiveness of the OXTR. A growing body of G x E work is indicating that rs53576G homozygosity becomes disadvantageous for later mental health under early adverse conditions but further research to extend these findings to eating pathology is needed. The GWAS approach would benefit this area of knowledge