15 research outputs found

    Inspection time and general speed of processing

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    Recent research suggests that the relationship between inspection time (IT) and psychometric intelligence arises because IT is a measure of general speed of processing (Gs). However, hierarchical models of intelligence propose several distinct speed of processing factors; this study examines IT in relation to these multiple speed factors. Participants (N=102) completed tests of speed of processing yielding 18 measures. Factor analysis revealed a second order general speed factor (Gs) and four group factors: perceptual speed, visualisation speed, decision time and movement time. IT correlated with a visualisation speed factor (r=0.36) and with a perceptual speed factor (r=0.28). However, the correlation between IT and perceptual speed was near-zero when the correlation with visualisation speed was partialled out. These findings are consistent with the notion that IT is a measure of Gs but suggest that IT most directly measures speed of visualisation processes. These results are also congruent with research on the psychophysics of IT.Tess A. O’Connor and Nicholas R. Burnshttp://www.elsevier.com/wps/find/journaldescription.cws_home/603/description#descriptio

    Multidecadal Basal Melt Rates and Structure of the Ross Ice Shelf, Antarctica, Using Airborne Ice Penetrating Radar

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    Basal melting of ice shelves is a major source of mass loss from the Antarctic Ice Sheet. In situ measurements of ice shelf basal melt rates are sparse, while the more extensive estimates from satellite altimetry require precise information about firn density and characteristics of near‐surface layers. We describe a novel method for estimating multidecadal basal melt rates using airborne ice penetrating radar data acquired during a 3‐year survey of the Ross Ice Shelf. These data revealed an ice column with distinct upper and lower units whose thicknesses change as ice flows from the grounding line toward the ice front. We interpret the lower unit as continental meteoric ice that has flowed across the grounding line and the upper unit as ice formed from snowfall onto the relatively flat ice shelf. We used the ice thickness difference and strain‐induced thickness change of the lower unit between the survey lines, combined with ice velocities, to derive basal melt rates averaged over one to six decades. Our results are similar to satellite laser altimetry estimates for the period 2003–2009, suggesting that the Ross Ice Shelf melt rates have been fairly stable for several decades. We identify five sites of elevated basal melt rates, in the range 0.5–2 m a⁻Âč, near the ice shelf front. These hot spots indicate pathways into the sub‐ice‐shelf ocean cavity for warm seawater, likely a combination of summer‐warmed Antarctic Surface Water and modified Circumpolar Deep Water, and are potential areas of ice shelf weakening if the ocean warms

    Freezing of ridges and water networks preserves the Gamburtsev Subglacial Mountains for millions of years

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    Once an ice sheet grows beyond a critical thickness, the basal thermal regime favors melting and development of subglacial water networks. Subglacial water is necessary for bedrock erosion, but the exact mechanisms that lead to preservation of subglacial topography are unclear. Here we resolve the freezing mechanisms that lead to long-term, high-altitude preservation across the Gamburtsev Subglacial Mountains in East Antarctica. Analyses of a comprehensive geophysical data set reveal a large-scale water network along valley floors. The ice sheet often drives subglacial water up steep topography where it freezes along high ridges beneath thinner ice. Statistical tests of hypsometry show the Gamburtsevs resemble younger midlatitude mountains, indicating exceptional preservation. We conclude that the Gamburtsevs have been shielded from erosion since the latest Eocene (∌34 Ma). These freezing mechanisms likely account for the spatial and temporal patterns of erosion and preservation seen in other glaciated mountain ranges

    New boundary conditions for the West Antarctic ice sheet: subglacial topography beneath Pine Island Glacier

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    Predictions about future changes in the Amundsen Sea sector of the West Antarctic ice sheet (WAIS) have been hampered by poorly known subglacial topography. Extensive airborne survey has allowed us to derive improved subglacial topography for the Pine Island Glacier basin. The trunk of this glacier lies in a narrow, 250-km long, 500-m deep sub-glacial trough, suggesting a long-lived and constrained ice stream. Two tributaries lie in similar troughs, others lie in less defined, shallower troughs. The lower basin of the glacier is surrounded by bedrock, which, after deglaciation and isostatic rebound, could rise above sea level. This feature would impede ice-sheet collapse initiated near the grounding line of this glacier, and prevent its progress into the deepest portions of WAIS. The inland-slope of the bed beneath the trunk of the glacier, however, confirms potential instability of the lower basin, containing sufficient ice to raise global sea by ∌24 cm

    ALDH2 mediates 5-nitrofuran activity in multiple species

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    Understanding how drugs work in vivo is critical for drug design and for maximizing the potential of currently available drugs. 5-nitrofurans are a class of pro-drugs widely used to treat bacterial and trypanosome infections, but despite relative specificity 5-nitrofurans often cause serious toxic side-effects in people. Here, we use yeast, zebrafish and human in vitro systems to assess the biological activity of 5-nitrofurans, and identify a conserved interaction between aldehyde dehydrogenase (ALDH) 2 and 5-nitrofurans across these species. In addition, we show that the activity of nifurtimox, a 5-nitrofuran anti-trypanosome pro-drug, is dependent on zebrafish Aldh2 and that nifurtimox is a substrate for human ALDH2. This study reveals a conserved and biologically relevant ALDH2-5-nitrofuran interaction that may have important implications for managing the toxicity of 5nitrofuran treatment.PostprintPeer reviewe
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