4,400 research outputs found

    Addressing Homelessness Through Religion

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    Every time I pass by a man in the street holding up a piece of cardboard saying “Homeless, Will Work for Food”, a little girl standing next to her mother by the side of the road begging for money, or families sleeping in tents underneath bridges on vacant industrial property or by shopping malls, it makes me question why the US is able to spend billions to help poor countries in the world but hasn\u27t solved its own problems. Reading Forbes magazine that ranked the 100 largest US charities in 2018, I am surprised to see many US charities such as Americares Foundation, Habitat For Humanity International, and Food For The Poor are rated as top ranking for their large revenue and high percentage of charitable commitment to support for international needs; while day by day I see more homeless people roaming around the streets, sleeping by their carts, or getting in long lines waiting for a place to stay at the homeless shelters in my community and nearby cities. Insufficient income and lack of affordable housing are the leading causes of homelessness. Homelessness not only affects those that are homeless, it affects everyone living in the community

    Blooming Lotus

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    While reflecting on my poetry chapbook, Blooming Lotus, I ask myself what I was trying to accomplish by creating the chapbook. I have always been interested in my East Asian culture, but growing up as an Asian American has resulted in some ignorance in regards to the topic. I wanted to explore more of my own heritage through the creation of this chapbook by writing poems inspired by East Asian culture. Not only did I want to expose myself to East Asian culture but I also wanted to expose my readers to it as well. Most of my poems required research, which mostly was through the internet but I was able to reach out to my parents and relatives to share their personal stories with me. I enjoyed being able to learn about my family\u27s background as they were immigrants during the Vietnam War and enjoyed being able to hear all the stories that have been passed down from generations. I feel that I was able to learn more about my culture through this chapbook and able to portray it to others as well through my writing

    Entanglement of purification: from spin chains to holography

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    Purification is a powerful technique in quantum physics whereby a mixed quantum state is extended to a pure state on a larger system. This process is not unique, and in systems composed of many degrees of freedom, one natural purification is the one with minimal entanglement. Here we study the entropy of the minimally entangled purification, called the entanglement of purification, in three model systems: an Ising spin chain, conformal field theories holographically dual to Einstein gravity, and random stabilizer tensor networks. We conjecture values for the entanglement of purification in all these models, and we support our conjectures with a variety of numerical and analytical results. We find that such minimally entangled purifications have a number of applications, from enhancing entanglement-based tensor network methods for describing mixed states to elucidating novel aspects of the emergence of geometry from entanglement in the AdS/CFT correspondence.Comment: 40 pages, multiple figures. v2: references added, typos correcte

    Evolutionary repression of chondrogenic genes in the vertebrate osteoblast

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    University of Saskatchewan, Natural Sciences and Engineering Research Council of Canada. Grant Numbers: RGPIN 2014‐05563, RGPIN 435655‐201Peer ReviewedGene expression in extant animals might reveal how skeletal cells have evolved over the past 500 million years. The cells that make up cartilage (chondrocytes) and bone (osteoblasts) express many of the same genes, but they also have important molecular differences that allow us to distinguish them as separate cell types. For example, traditional studies of later-diverged vertebrates, such as mouse and chick, defined the genes Col2a1 and sex-determining region Y-box 9 as cartilage-specific. However, recent studies have shown that osteoblasts of earlier-diverged vertebrates, such as frog, gar, and zebrafish, express these 'chondrogenic' markers. In this review, we examine the resulting hypothesis that chondrogenic gene expression became repressed in osteoblasts over evolutionary time. The amphibian is an underexplored skeletal model that is uniquely positioned to address this hypothesis, especially given that it diverged when life transitioned from water to land. Given the relationship between phylogeny and ontogeny, a novel discovery for skeletal cell evolution might bolster our understanding of skeletal cell development

    Urinary Phthalate Metabolites and Biomarkers of Oxidative Stress in a Mexican-American Cohort: Variability in Early and Late Pregnancy.

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    People are exposed to phthalates through their wide use as plasticizers and in personal care products. Many phthalates are endocrine disruptors and have been associated with adverse health outcomes. However, knowledge gaps exist in understanding the molecular mechanisms associated with the effects of exposure in early and late pregnancy. In this study, we examined the relationship of eleven urinary phthalate metabolites with isoprostane, an established marker of oxidative stress, among pregnant Mexican-American women from an agricultural cohort. Isoprostane levels were on average 20% higher at 26 weeks than at 13 weeks of pregnancy. Urinary phthalate metabolite concentrations suggested relatively consistent phthalate exposures over pregnancy. The relationship between phthalate metabolite concentrations and isoprostane levels was significant for the sum of di-2-ethylhexyl phthalate and the sum of high molecular weight metabolites with the exception of monobenzyl phthalate, which was not associated with oxidative stress at either time point. In contrast, low molecular weight metabolite concentrations were not associated with isoprostane at 13 weeks, but this relationship became stronger later in pregnancy (p-value = 0.009 for the sum of low molecular weight metabolites). Our findings suggest that prenatal exposure to phthalates may influence oxidative stress, which is consistent with their relationship with obesity and other adverse health outcomes

    GME: Gym in Medical Education-Maintaining Physical and Mental Well Being During the COVID-19 Pandemic

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