21,865 research outputs found
Distributed space-time-frequency block code for cognitive wireless relay networks
In this study, the authors consider cooperative transmission in cognitive wireless relay networks (CWRNs) over frequency-selective fading channels. They propose a new distributed space-time–frequency block code (DSTFBC) for a two-hop non-regenerative CWRN, where a primary source node and multiple secondary source nodes convey information data to their desired primary destination node and multiple secondary destination nodes via multiple cognitive relay nodes with dynamic spectrum access. The proposed DSTFBC is designed to achieve spatial diversity gain as well as allow for low-complexity decoupling detection at the receiver. Pairwise error probability is then analysed to study the achievable diversity gain of the proposed DSTFBC for different channel models including Rician fading and mixed Rayleigh–Rician fading
Performance analysis of cooperative transmission for cognitive wireless relay networks
In this paper, we consider cooperative transmission in cognitive wireless relay networks (CWRNs) over frequency-selective fading channels. We propose a new distributed space-time-frequency block code (DSTFBC) for a two-hop nonregenerative CWRN, where a primary source node and multiple secondary source nodes convey information data to their desired primary destination node and multiple secondary destination nodes via multiple cognitive relay nodes with dynamic spectrum access. The proposed DSTFBC is designed to achieve spatial diversity gain as well as allow for low-complexity decoupling detection at the receiver. Pairwise error probability is then analysed to study the achievable diversity gain of the proposed DSTFBC for different channel models including Rician fading and mixed Rayleigh-Rician fading
SLE_k: correlation functions in the coefficient problem
We apply the method of correlation functions to the coefficient problem in
stochastic geometry. In particular, we give a proof for some universal patterns
conjectured by M. Zinsmeister for the second moments of the Taylor coefficients
for special values of kappa in the whole-plane Schramm-Loewner evolution
(SLE_kappa). We propose to use multi-point correlation functions for the study
of higher moments in coefficient problem. Generalizations related to the
Levy-type processes are also considered. The exact multifractal spectrum of
considered version of the whole-plane SLE_kappa is discussed
Cross-Kerr nonlinearity between continuous-mode coherent states and single photons
Weak cross-Kerr nonlinearities between single photons and coherent states are
the basis for many applications in quantum information processing. These
nonlinearities have so far mainly been discussed in terms of highly idealized
single-mode models. We develop a general theory of the interaction between
continuous-mode photonic pulses and apply it to the case of a single photon
interacting with a coherent state. We quantitatively study the validity of the
usual single-mode approximation using the concepts of fidelity and conditional
phase. We show that high fidelities, non-zero conditional phases and high
photon numbers are compatible, under conditions where the pulses fully pass
through each other and where unwanted transverse-mode effects are suppressed.Comment: 8 pages, 2 figures, more general results in section V
Classical analogy for the deflection of flux avalanches by a metallic layer
Sudden avalanches of magnetic flux bursting into a superconducting sample
undergo deflections of their trajectories when encountering a conductive layer
deposited on top of the superconductor. Remarkably, in some cases flux is
totally excluded from the area covered by the conductive layer. We present a
simple classical model that accounts for this behaviour and considers a
magnetic monopole approaching a semi-infinite conductive plane. This model
suggests that magnetic braking is an important mechanism responsible for
avalanche deflection.Comment: 14 pages, 5 figure
Fish schooling as a basis for vertical axis wind turbine farm design
Most wind farms consist of horizontal axis wind turbines (HAWTs) due to the
high power coefficient (mechanical power output divided by the power of the
free-stream air through the turbine cross-sectional area) of an isolated
turbine. However when in close proximity to neighbouring turbines, HAWTs suffer
from a reduced power coefficient. In contrast, previous research on vertical
axis wind turbines (VAWTs) suggests that closely-spaced VAWTs may experience
only small decreases (or even increases) in an individual turbine's power
coefficient when placed in close proximity to neighbours, thus yielding much
higher power outputs for a given area of land. A potential flow model of
inter-VAWT interactions is developed to investigate the effect of changes in
VAWT spatial arrangement on the array performance coefficient, which compares
the expected average power coefficient of turbines in an array to a
spatially-isolated turbine. A geometric arrangement based on the configuration
of shed vortices in the wake of schooling fish is shown to significantly
increase the array performance coefficient based upon an array of 16x16 wind
turbines. Results suggest increases in power output of over one order of
magnitude for a given area of land as compared to HAWTs.Comment: Submitted for publication in BioInspiration and Biomimetics. Note:
The technology described in this paper is protected under both US and
international pending patents filed by the California Institute of Technolog
Towards connecting people, locations and real-world events in a cellular network
The success of personal mobile communication technologies has led an emerging expansion of the telecommunication infrastructure but also to an explosion to mobile broadband data traffic as more and more people completely rely on their mobile devices, either for work or entertainment. The continuously interaction of their mobile devices with the mobile network infrastructure creates digital traces that can be easily logged by the network operators. These digital traces can be further used, apart from billing and resource management, for large-scale population monitoring using mobile traffic analysis. They could be integrated into intelligent systems that could help at detecting exceptional events such as riots, protests or even at disaster preventions with minimal costs and improve people safety and security, or even save lives. In this paper we study the use of fully anonymized and highly aggregate cellular network data, like Call Detail Records (CDRs) to analyze the telecommunication traffic and connect people, locations and events. The results show that by analyzing the CDR data exceptional spatio-temporal patterns of mobile data can be correlated to real-world events. For example, high user network activity was mapped to religious festivals, such as Ramadan, Le Grand Magal de Touba and the Tivaouane Maouloud festival. During the Ramadan period it was noticed that the communication pattern doubled during the night with a slow start during the morning and along the day. Furthermore, a peak increase in the number of voice calls and voice calls duration in the area of Kafoutine was mapped to the Casamance Conflict in the area which resulted in four deaths. Thus, these observations could be further used to develop an intelligent system that detects exceptional events in real-time from CDRs data monitoring. Such system could be used in intelligent transportation management, urban planning, emergency situations, network resource allocation and performance optimization, etc
RhoA function in lamellae formation and migration is regulated by the alpha6beta4 integrin and cAMP metabolism
Clone A colon carcinoma cells develop fan-shaped lamellae and exhibit random migration when plated on laminin, processes that depend on the ligation of the alpha6beta4 integrin. Here, we report that expression of a dominant negative RhoA (N19RhoA) in clone A cells inhibited alpha6beta4-dependent membrane ruffling, lamellae formation, and migration. In contrast, expression of a dominant negative Rac (N17Rac1) had no effect on these processes. Using the Rhotekin binding assay to assess RhoA activation, we observed that engagement of alpha6beta4 by either antibody-mediated clustering or laminin attachment resulted in a two- to threefold increase in RhoA activation, compared with cells maintained in suspension or plated on collagen. Antibody-mediated clustering of beta1 integrins, however, actually suppressed Rho A activation. The alpha6beta4-mediated interaction of clone A cells with laminin promoted the translocation of RhoA from the cytosol to membrane ruffles at the edges of lamellae and promoted its colocalization with beta1 integrins, as assessed by immunofluorescence microscopy. In addition, RhoA translocation was blocked by inhibiting phosphodiesterase activity and enhanced by inhibiting the activity of cAMP-dependent protein kinase. Together, these results establish a specific integrin-mediated pathway of RhoA activation that is regulated by cAMP and that functions in lamellae formation and migration
Functional rescue of dystrophin deficiency in mice caused by frameshift mutations using Campylobacter jejuni Cas9
Duchenne muscular dystrophy (DMD) is a fatal, X-linked muscle wasting disease caused by mutations in the DMD gene. In 51% of DMD cases, a reading frame is disrupted because of deletion of several exons. Here, we show that CjCas9 derived from Campylobacter jejuni can be
used as a gene editing tool to correct an out-of-frame Dmd exon in Dmd knockout mice. Herein, we used Cas9 derived from S. pyogenes to generate Dmd knockout (KO) mice with a frameshift mutation in Dmd gene. Then, we expressed CjCas9, its single-guide RNA, and the eGFP gene
in the tibialis anterior muscle of the Dmd KO mice using an all-in-one adeno-associated virus (AAV) vector. CjCas9 cleaved the target site in the Dmd gene efficiently in vivo and induced small insertions or deletions at the target site. This treatment resulted in conversion of the
disrupted Dmd reading frame from out-of-frame to in-frame, leading to the expression of dystrophin in the sarcolemma. Importantly, muscle strength was enhanced in the CjCas9-treated muscles, without off-target mutations, indicating high efficiency and specificity of CjCas9. This work suggests that in vivo DMD frame correction, mediated by CjCas9 has great potential for the treatment of DMD and other neuromuscular diseases
Bounds on Lorentz and CPT Violation from the Earth-Ionosphere Cavity
Electromagnetic resonant cavities form the basis of many tests of Lorentz
invariance involving photons. The effects of some forms of Lorentz violation
scale with cavity size. We investigate possible signals of violations in the
naturally occurring resonances formed in the Earth-ionosphere cavity.
Comparison with observed resonances places the first terrestrial constraints on
coefficients associated with dimension-three Lorentz-violating operators at the
level of 10^{-20} GeV.Comment: 8 pages REVTe
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