44,094 research outputs found
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Remarkably high abundance of presolar grains in interplanetary dust particles collected from the comet Grigg-Skjellerup dust stream
Isotopic studies of IDPs collected from the comet Grigg-Skjellerup dust stream reveal extremely high abundances of presolar grains in two of four IDPs. These abundances exceed those of any other extraterrestrial material analyzed and support a cometary origin for these IDPs
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Trends in long-term prescribing of dependence forming medicines
Using patient-level primary care data to estimate the extent to which antidepressant medicines are prescribed to people continuously for long periods of time.
Aim
This descriptive research used patient-level primary care data to estimate the extent to which antidepressant medicines are prescribed to people continuously for long periods of time. The study also drew on survey data and data on the number of prescriptions dispensed.
Findings
- The number of antidepressant prescriptions dispensed each year in England doubled between 2008 and 2018
- Survey data show that the proportion of adults reporting use of antidepressants in the past year increased in the 1990s, and again between 2007 and 2014
- The average length of time that antidepressants are continuously prescribed to people for has increased over time.
- Some types of antidepressants (for example, tricyclics and other antidepressants) tend to be prescribed for longer periods than other types (such as SSRIs).
- In 2014, one in twelve prescribing periods for tricyclics and other antidepressants lasted for three years or more
Methods
The analyses in this report are descriptive and show the overall prevalence of long-term prescribing in each year.
We used a sample of around 50,000 patients prescribed at least one antidepressant medicine between 2000 and 2017. This was drawn from the Clinical Practice Research Datalink (CPRD). The CPRD contains data about prescriptions issued by GPs (including the length and size of prescription) and characteristics of the patients prescribed to (such as their age, sex, and area where they live). Medicines were grouped for analysis into: tricyclics, selective serotonin reuptake inhibitors (SSRIs), and other ADMs. The length of individual prescriptions and continuous prescribing periods were derived using information on consultation dates, the quantity of tablets prescribed, and the numeric daily dose
Relationship Between Obesity and Periodontal Status in Vietnamese Patients
This study aims to investigate periodontal status, and the relationship between obesity and periodontal status in patients who first visited the Institute of Traditional Medicine, Ho Chi Minh City, Vietnam. 118 patients aged 18 or older, including 56 obese subjects (BMI≥27.5, mean age: 33.8, males: 11, females: 45) and 62 non-obese subjects (BMI<27.5, mean age: 34.3, males: 4, females: 58) were enrolled for a period of 5 months from February 2014 to June 2014. The information on socio-demographic characteristics and dental habits were collected by questionnaire. Periodontal status (PLI, GI, BOP, PD, CAL) was examined and the anthropometric index was measured. There was significantly higher prevalence of periodontitis (39.3%) in the obese group than the non-obese group (16.4%). Means of GI, BOP, PD, and CAL in obese subjects were significantly higher than those in non-obese subjects. Significantly higher percentages of subjects who had lower education, visited dental offices, scaled and polished their teeth regularly were in the non-obese group than in the obese group. Multiple logistic regression analysis revealed that age (OR=3.10), routine of dental visit (OR=3.34) and obesity (OR=2.79) were risk factors significantly related to periodontitis. Periodontal status in obese subjects was poorer than non-obese subjects. Obesity might be the risk factor for periodontitis in Vietnamese patients
Dynamics of horizontal-like maps in higher dimension
We study the regularity of the Green currents and of the equilibrium measure
associated to a horizontal-like map in C^k, under a natural assumption on the
dynamical degrees. We estimate the speed of convergence towards the Green
currents, the decay of correlations for the equilibrium measure and the
Lyapounov exponents. We show in particular that the equilibrium measure is
hyperbolic. We also show that the Green currents are the unique invariant
vertical and horizontal positive closed currents. The results apply, in
particular, to Henon-like maps, to regular polynomial automorphisms of C^k and
to their small pertubations.Comment: Dedicated to Professor Gennadi Henkin on the occasion of his 65th
birthday, 37 pages, to appear in Advances in Mat
The Higgs Sector on a Two-Sheeted Space Time
We present a general formalism based on the framework of non-commutative
geometry, suitable to the study the standard model of electroweak interactions,
as well as that of more general gauge theories. Left- and right-handed chiral
fields are assigned to two different sheets of space-time (a discretized
version of Kaluza-Klein theory). Scalar Higgs fields find themselves treated on
the same footing as the gauge fields, resulting in spontaneous symmetry
breaking in a natural and predictable way. We first apply the formalism to the
Standard Model, where one can predict the Higgs mass and the top Yukawa
coupling. We then study the left-right symmetric model, where we show that this
framework imposes constraints on the type and coefficients of terms appearing
in the Higgs potential.Comment: 24 pages, uses revtex
Influence of complex configurations on properties of pygmy dipole resonance in neutron-rich Ca isotopes
Starting from the quasiparticle random phase approximation based on the
Skyrme interaction SLy5, we study the effects of phonon-phonon coupling~(PPC)
on the low-energy electric dipole response in Ca. Using the same set
of parameters we describe available experimental data for Ca and
give prediction for Ca. The inclusion of the PPC results in the
formation of low-energy states. There is an impact of the PPC effect on
low-energy ~strength of Ca. The PPC effect on the electric
dipole polarizability is discussed. We predict a strong increase of the summed
~strength below 10MeV, with increasing neutron number from Ca till
Ca.Comment: 11 pages, 10 figure
Relative pay and job satisfaction: some new evidence
This paper investigates the determinants of job satisfaction using data from the National Educational Longitudinal Study. The determinants of interest include actual pay, relative pay, hours of work, job autonomy and several personal characteristics. We also investigate the determinants of satisfaction with pay conditional on a worker's satisfaction with other domains of job satisfaction, such as satisfaction with job security. We find that relative pay is statistically significant but that its effect on satisfaction with pay is relatively small. Job autonomy has a powerful influence on satisfaction with pay. So too does being black.
Isogeometric analysis for functionally graded microplates based on modified couple stress theory
Analysis of static bending, free vibration and buckling behaviours of
functionally graded microplates is investigated in this study. The main idea is
to use the isogeometric analysis in associated with novel four-variable refined
plate theory and quasi-3D theory. More importantly, the modified couple stress
theory with only one material length scale parameter is employed to effectively
capture the size-dependent effects within the microplates. Meanwhile, the
quasi-3D theory which is constructed from a novel seventh-order shear
deformation refined plate theory with four unknowns is able to consider both
shear deformations and thickness stretching effect without requiring shear
correction factors. The NURBS-based isogeometric analysis is integrated to
exactly describe the geometry and approximately calculate the unknown fields
with higher-order derivative and continuity requirements. The convergence and
verification show the validity and efficiency of this proposed computational
approach in comparison with those existing in the literature. It is further
applied to study the static bending, free vibration and buckling responses of
rectangular and circular functionally graded microplates with various types of
boundary conditions. A number of investigations are also conducted to
illustrate the effects of the material length scale, material index, and
length-to-thickness ratios on the responses of the microplates.Comment: 57 pages, 14 figures, 18 table
Structure of low-lying quadrupole states in nuclei near 132Sn
The properties of the low-lying 2^+ states in the even-even nuclei around
132Sn are studied within the quasiparticle random phase approximation. Starting
from a Skyrme interaction in the particle-hole channel and a density-dependent
zero-range interaction in the particle-particle channel, we use the finite rank
separable approach in our investigation. It is found that the fourth 2^+ state
in 132Te could be a good candidate for a mixed-symmetry state.Comment: 6 pages, 2 figures, proceedings of International Conference on
Nuclear Structure and Related Topics (NSRT09), June 2009, JINR, Dubna, Russi
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