Commentary on the article: “Maintenance of Wellness in Patients With Obsessive-Compulsive Disorder Who Discontinue Medication After Exposure/Response Prevention Augmentation A Randomized Clinical Trial”

© 2022 The Authors. Published by Elsevier Inc. This is an open access article distributed under the Creative Commons Non Commercial-No Derivatives Attribution License, to view a copy of the license, see: https://creativecommons.org/licenses/by-nc-nd/4.0/Peer reviewe

Analysis of the motivation system and group cooperation on the example of the Ukrainian enterprise "Tempo"

Praca magisterska dotyczy analizowania współpracy pomiędzy ludźmi, oraz na jakim poziomie jest motywowanie pracowników w ukraińskim przedsiębiorstwie. Rozdział pierwszy obejmuje pojęcie grupy oraz zachowania grupowego w organizacji. W podrozdziałach zostały opisane mechanizmy grupowe, konflikty w miejscu pracy oraz metody ich rozwiązywania, a także istotność rozwoju personelu, zabezpieczenie konkurencyjności w przedsiębiorstwie. W drugim rozdziale przedstawiono pojęcie motywacji pracowników i system zwiększenia skuteczności pracy organizacji, jakie są bodźce materialne i niematerialne zachęcające pracowników w ujęciu krajowym i zagranicznym. W trzecim rozdziale została opisana wybrana spółka badana. Został rozpatrzony problem systemu motywacyjnego w organizacji poprzez analizę i ocenę głównych elementów układu pracy personelu. Uzyskano sposoby polepszenia systemu motywacyjnego w organizacji. Metody i techniki badawcze, wykorzystane w badaniu przedsiębiorstwa, są szczególnie bazujące na dokumentacji firmy, wywiadach eksperckich i kwestionariuszowych, które już były przedstawione w niektórych raportach, archiwalnych dokumentach oraz sprawozdaniach finansowych.Master's thesis is about analyzing cooperation between people and on what level is the motivation of employees in a Ukrainian enterprise. Chapter one covers the concept of group and group behavior in an organization. Subsection describe group mechanisms, conflicts in the workplace and methods of solving them, as well as the importance of staff development, securing competitiveness in the enterprise. The second chapter presents the concept of employee motivation and the system for enhancing the efficiency of the work of the organization, which are tangible and intangible incentives for employees in both domestic and foreign. The third chapter describes the selected research company. The problem of the motivational system in the organization has been addressed by analyzing and evaluating the main elements of the staff working system. There are ways to improve the incentive system in that organization. The research methods and techniques which was used are especially based on company documentation, expert interviews and questionnaires, which have already been reported in some reports, archival documents and financial reports

New perspectives in the treatment of body dysmorphic disorder [version 1; referees: 2 approved]

Body dysmorphic disorder (BDD) is a disabling illness with a high worldwide prevalence. Patients demonstrate a debilitating preoccupation with one or more perceived defects, often marked by poor insight or delusional convictions. Multiple studies have suggested that selective serotonin reuptake inhibitors and various cognitive behavioral therapy modalities are effective first-line treatments in decreasing BDD severity, relieving depressive symptoms, restoring insight, and increasing quality of life. Selective serotonin reuptake inhibitors have also recently been shown to be effective for relapse prevention. This review provides a comprehensive summary of the current understanding of BDD, including its clinical features, epidemiology, genetics, and current treatment modalities. Additional research is needed to fully elucidate the relationship between BDD and comorbid illnesses such as obsessive–compulsive-related disorders and depression and to develop therapies for refractory patients and those who have contraindications for pharmacological intervention

Predator Stress in Mice with Differences in Behavioral Copying: a Model of Human Behavior in Extreme Situations

Proceedings of the 9th International Multidisciplinary Conference «Stress and Behavior» Saint-Petersburg, Russia, 16–19 May 2005.Increasing pressure of environmental stressful stimuli worldwide, such as fear of terror attacks and dramatic climate catastrophes raises the level of stress in the society, thus, resulting in a higher risk of psychosomatic disorders and a lower quality of life. This requires further improvement of stress medicine and, particularly, development of adequate animal models that would reflect individual differences in vulnerability to stress during extreme environmental danger. Here we propose a paradigm of acute predator stress in mice as a model of extreme environmental stress in humans. In this study, we related individual differences of animal’s stress-responsiveness in this model to parameters of behavioral coping in other paradigms. First, male CD1 mice were tested in the forced swim test, resident-intruder paradigm and sucrose test. Several weeks later, they were exposed to a predator stress for a time period of 9 h. Then they were placed into a small container and introduced into a cage, which contained a rat; mice were water- and food-deprived during the entire period of stress. A subgroup of mice received an i.p. injection of antidepressant imipramine (30 mg/kg) 30 min prior to stress. Non-stressed animals remained untreated and were kept in regular animal facility. Immediately after the stress period, stressed and non-stressed animals were tested for their vertical activity and preference to sucrose. Stressed mice exhibited an increased preference to sucrose and total consumption of liquids as compared to control, while their locomotor activity remained unaltered. Administration of imipramine before stress prevented stress-induced changes in sucrose preference. The mice that demonstrated subdominant copying in the resident-intruder test, demonstrated significantly higher values of consumed liquid as compared to dominant individuals, while in baseline conditions parameters of sucrose test did not differ between subgroups. Dominant mice demonstrated a larger variability in preference to sucrose measured after stress than their subdominant counterparts. Dominant animals had higher scores of vertical activity in the novel cage test in comparison to subdominant mice. In subdominant individuals, vertical activity correlated with preference to sucrose that was not a case for dominant animals. In dominant mice, the increase in preference to sucrose negatively correlated with latency of attack. Parameters of floating behavior in the forced swim did not correlate with any of variables measured before nor after stress. Our experimental approach possibly may be useful in modeling of individual features of human behavior and stress-responsiveness in extreme situations

Predator Stress in Mice with Differences in Behavioral Copying: a Model of Human Behavior in Extreme Situations

Proceedings of the 9th International Multidisciplinary Conference «Stress and Behavior» Saint-Petersburg, Russia, 16–19 May 2005.Increasing pressure of environmental stressful stimuli worldwide, such as fear of terror attacks and dramatic climate catastrophes raises the level of stress in the society, thus, resulting in a higher risk of psychosomatic disorders and a lower quality of life. This requires further improvement of stress medicine and, particularly, development of adequate animal models that would reflect individual differences in vulnerability to stress during extreme environmental danger. Here we propose a paradigm of acute predator stress in mice as a model of extreme environmental stress in humans. In this study, we related individual differences of animal’s stress-responsiveness in this model to parameters of behavioral coping in other paradigms. First, male CD1 mice were tested in the forced swim test, resident-intruder paradigm and sucrose test. Several weeks later, they were exposed to a predator stress for a time period of 9 h. Then they were placed into a small container and introduced into a cage, which contained a rat; mice were water- and food-deprived during the entire period of stress. A subgroup of mice received an i.p. injection of antidepressant imipramine (30 mg/kg) 30 min prior to stress. Non-stressed animals remained untreated and were kept in regular animal facility. Immediately after the stress period, stressed and non-stressed animals were tested for their vertical activity and preference to sucrose. Stressed mice exhibited an increased preference to sucrose and total consumption of liquids as compared to control, while their locomotor activity remained unaltered. Administration of imipramine before stress prevented stress-induced changes in sucrose preference. The mice that demonstrated subdominant copying in the resident-intruder test, demonstrated significantly higher values of consumed liquid as compared to dominant individuals, while in baseline conditions parameters of sucrose test did not differ between subgroups. Dominant mice demonstrated a larger variability in preference to sucrose measured after stress than their subdominant counterparts. Dominant animals had higher scores of vertical activity in the novel cage test in comparison to subdominant mice. In subdominant individuals, vertical activity correlated with preference to sucrose that was not a case for dominant animals. In dominant mice, the increase in preference to sucrose negatively correlated with latency of attack. Parameters of floating behavior in the forced swim did not correlate with any of variables measured before nor after stress. Our experimental approach possibly may be useful in modeling of individual features of human behavior and stress-responsiveness in extreme situations

THE EFFECT OF INACTIVATION OF MAST CELLS ON REPARATIVE REGENERATION OF THE SKIN

The effect of inactivation of mast cells on reparative regeneration of the skin was investigated. The mast cells membrane’s stabilization with Ketotifen retards reparative reactions. Mast cells act systematically