Creating a National Network of Energy Discovery-Innovation Institutes: A Step Toward America's Energy Sustainability

Draft 1.1http://deepblue.lib.umich.edu/bitstream/2027.42/88576/1/2008_NREN_Draft_1.2.pd

Discovery potential of xenon-based neutrinoless double beta decay experiments in light of small angular scale CMB observations

The South Pole Telescope (SPT) has probed an expanded angular range of the CMB temperature power spectrum. Their recent analysis of the latest cosmological data prefers nonzero neutrino masses, mnu = 0.32+-0.11 eV. This result, if confirmed by the upcoming Planck data, has deep implications on the discovery of the nature of neutrinos. In particular, the values of the effective neutrino mass involved in neutrinoless double beta decay (bb0nu) are severely constrained for both the direct and inverse hierarchy, making a discovery much more likely. In this paper, we focus in xenon-based bb0nu experiments, on the double grounds of their good performance and the suitability of the technology to large-mass scaling. We show that the current generation, with effective masses in the range of 100 kg and conceivable exposures in the range of 500 kg year, could already have a sizable opportunity to observe bb0nu events, and their combined discovery potential is quite large. The next generation, with an exposure in the range of 10 ton year, would have a much more enhanced sensitivity, in particular due to the very low specific background that all the xenon technologies (liquid xenon, high-pressure xenon and xenon dissolved in liquid scintillator) can achieve. In addition, a high-pressure xenon gas TPC also features superb energy resolution. We show that such detector can fully explore the range of allowed effective Majorana masses, thus making a discovery very likely

Micromegas operation in high pressure xenon: charge and scintillation readout

The operational characteristics of a Micromegas operating in pure xenon at the pressure range of 1 to 10 bar are investigated. The maximum charge gain achieved in each pressure is approximately constant, around 4x10^2, for xenon pressures up to 5 bar and decreasing slowly above this pressure down to values somewhat above 10^2 at 10 bar. The MM presents the highest gains for xenon pressures above 4 bar, when compared to other micropattern gaseous multipliers. The lowest energy resolution obtained for X-rays of 22.1 keV exhibits a steady increase with pressure, from 12% at 1bar to about 32% at 10 bar. The effective scintillation yield, defined as the number of photons exiting through the MM mesh holes per primary electron produced in the conversion region was calculated. This yield is about 2x10^2 photons per primary electron at 1 bar, increasing to about 6x10^2 at 5 bar and, then, decreasing again to 2x10^2 at 10 bar. The readout of this scintillation by a suitable photosensor will result in higher gains but with increased statistical fluctuations.Comment: 22 pages, 11 figure

Solar neutrino-electron scattering as background limitation for double beta decay

The background on double beta decay searches due to elastic electron scattering of solar neutrinos of all double beta emitters with Q-value larger than 2 MeV is calculated, taking into account survival probability and flux uncertainties of solar neutrinos. This work determines the background level to be [1-2]E-7 counts /keV/kg/yr, depending on the precise Q-value of the double beta emitter. It is also shown that the background level increases dramatically if going to lower Q-values. Furthermore, studies are done for various detector systems under consideration for next generation experiments. It was found that experiments based on loaded liquid scintillator have to expect a higher background. Within the given nuclear matrix element uncertainties any approach exploring the normal hierarchy has to face this irreducible background, which is a limitation on the minimal achievable background for purely calorimetric approaches. Large scale liquid scintillator experiments might encounter this problem already while exploring the inverted hierarchy. Potential caveats by using more sophisticated experimental setups are also discussed

Primary and secondary scintillation measurements in a xenon Gas Proportional Scintillation Counter

NEXT is a new experiment to search for neutrinoless double beta decay using a 100 kg radio-pure high-pressure gaseous xenon TPC. The detector requires excellent energy resolution, which can be achieved in a Xe TPC with electroluminescence readout. Hamamatsu R8520-06SEL photomultipliers are good candidates for the scintillation readout. The performance of this photomultiplier, used as VUV photosensor in a gas proportional scintillation counter, was investigated. Initial results for the detection of primary and secondary scintillation produced as a result of the interaction of 5.9 keV X-rays in gaseous xenon, at room temperature and at pressures up to 3 bar, are presented. An energy resolution of 8.0% was obtained for secondary scintillation produced by 5.9 keV X-rays. No significant variation of the primary scintillation was observed for different pressures (1, 2 and 3 bar) and for electric fields up to 0.8 V cm-1 torr-1 in the drift region, demonstrating negligible recombination luminescence. A primary scintillation yield of 81 \pm 7 photons was obtained for 5.9 keV X-rays, corresponding to a mean energy of 72 \pm 6 eV to produce a primary scintillation photon in xenon.Comment: 16 pages, 10 figures, accepted for publication in JINS

Characterization of microbulk detectors in argon- and neon-based mixtures

A recent Micromegas manufacturing technique, so called Microbulk, has been developed, improving the uniformity and stability of this kind of detectors. Excellent energy resolutions have been obtained, reaching values as low as 11% FWHM at 5.9 keV in Ar+5%iC4H10. This detector has other advantages like its flexible structure, low material budget and high radio-purity. Two microbulk detectors with gaps of 50 and 25 um have been characterized in argon- and neon-based mixtures with ethane, isobutane and cyclohexane. The results will be presented and discussed. The gain curves have been fitted to the Rose-Korff gain model and dependences of the electron mean free path and the threshold energy for ionization have been obtained. The possible relation between these two parameters and the energy resolution will be also discussed.Comment: Submitted to the Journal of Instrumentatio

Data and product needs for influenza immunization programs in low- and middle-income countries: Rationale and main conclusions of the WHO preferred product characteristics for next-generation influenza vaccines.

In 2017, WHO convened a working group of global experts to develop the Preferred Product Characteristics (PPC) for Next-Generation Influenza Vaccines. PPCs are intended to encourage innovation in vaccine development. They describe WHO preferences for parameters of vaccines, in particular their indications, target groups, implementation strategies, and clinical data needed for assessment of safety and efficacy. PPCs are shaped by the global unmet public health need in a priority disease area for which WHO encourages vaccine development. These preferences reflect WHO's mandate to promote the development of vaccines with high public health impact and suitability in Low- and Middle-Income Countries (LMIC). The target audience is all entities intending to develop or to achieve widespread adoption of a specific influenza vaccine product in these settings. The working group determined that existing influenza vaccines are not well suited for LMIC use. While many developed country manufactures and research funders prioritize influenza vaccine products for use in adults and the elderly, most LMICs do not have sufficiently strong health systems to deliver vaccines to these groups. Policy makers from LMICs are expected to place higher value on vaccines indicated for prevention of severe illness, however the clinical development of influenza vaccines focuses on demonstrating prevention of any influenza illness. Many influenza vaccine products do not meet WHO standards for programmatic suitability of vaccines, which introduces challenges when vaccines are used in low-resource settings. And finally, current vaccines do not integrate well with routine immunization programs in LMICs, given age of vaccine licensure, arbitrary expiration dates timed for temperate country markets, and the need for year-round immunization in countries with prolonged influenza seasonality. While all interested parties should refer to the full PPC document for details, in this article we highlight data needs for new influenza vaccines to better demonstrate the value proposition in LMICs