409 research outputs found

    PedagogĂ­as de la precariedad en el orden educativo neoliberal. Inseguridad y recomposiciĂłn de las posibilidades en el actual contexto polĂ­tico-pedagĂłgico

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    The aim of this article is to analyse how neoliberal principles in education create a state of precariousness. The question that will guide the problematisation and the argumentation of the work is: What is the «status» of precariousness in the current order and how does it manifest itself - expressly or inadvertently - in the contemporary educational field? In order to address this question, a theoretical-analytical exercise has been carried out based on a review of relevant literature on the relationship between neoliberalisation and education. As a central hypothesis, we propose that the processes of precarisation constitute an objective necessity for the expansion and reproduction of the new neoliberal order. In addition, this order requires the production of a specific type of subjectivity that normalizes «precariousness» as a new historical condition, producing a particular notion of subjectivity and agency. The intersection between objective needs and the production of a particular subjectivity is produced in the cultural space through «pedagogies of precariousness». The installation of such pedagogies in formal education systems will be verified through the analysis of three predominant figures: the entrepreneur, the apprentice of competences and the teacher as technician. Finally, it is analysed how a «pedagogy of possibilities» could be opposed to «pedagogies of precariousness», enabling other forms of educational relations and new political-pedagogical horizons

    Conditional linearizability criteria for a system of third-order ordinary differential equations

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    We provide linearizability criteria for a class of systems of third-order ordinary differential equations (ODEs) that is cubically semi-linear in the first derivative, by differentiating a system of second-order quadratically semi-linear ODEs and using the original system to replace the second derivative. The procedure developed splits into two cases, those where the coefficients are constant and those where they are variables. Both cases are discussed and examples given

    Use of Complex Lie Symmetries for Linearization of Systems of Differential Equations - II: Partial Differential Equations

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    The linearization of complex ordinary differential equations is studied by extending Lie's criteria for linearizability to complex functions of complex variables. It is shown that the linearization of complex ordinary differential equations implies the linearizability of systems of partial differential equations corresponding to those complex ordinary differential equations. The invertible complex transformations can be used to obtain invertible real transformations that map a system of nonlinear partial differential equations into a system of linear partial differential equation. Explicit invariant criteria are given that provide procedures for writing down the solutions of the linearized equations. A few non-trivial examples are mentioned.Comment: This paper along with its first part ODE-I were combined in a single research paper "Linearizability criteria for systems of two second-order differential equations by complex methods" which has been published in Nonlinear Dynamics. Due to citations of both parts I and II these are not replaced with the above published articl

    Spatially resolved generation profiles for building, land and water-bound PV: a case study of four Dutch energy transition scenarios

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    Alongside a transition from steerable and centralized traditional electricity generation to intermittent and more decentralized renewable electricity generation from solar panels and wind turbines, Dutch energy transition scenarios project a widespread deployment of heat pumps and electric vehicles towards 2050. While clearly contributing to the decarbonization of the Dutch energy system, these developments impose challenges regarding electricity supply-demand mismatch and grid congestion. Spatially resolved electricity demand and supply profiles are required to gain a better insight into where and when such problems are likely to occur within the different scenarios. The present paper focuses on Dutch solar energy supply and features the construction of geodatabases of scenario-specific, spatially resolved electricity generation profiles for building, land and water-bound PV. Country-level PV capacities are geographically distributed based on spatial variance in roof PV potential and availability of suitable land and water use areas. Corresponding electricity generation profiles are constructed using historical meteorological measurements, a diffuse fraction model and a anisotropic transposition model. Empirically found performance ratio profiles are applied to account for a multitude of performance loss factors, including shading, dust and inverter efficiency. In 2050, building-bound capacity is projected to show only limited overlap with both land-bound and water-bound PV capacity. On the other hand, regions with considerable water-bound PV capacity also tend to show considerable land-bound PV capacity. Compared to the present-day situation, yearly country-level PV electricity generation is projected to be a factor 18.5, 15.7, or 7.7 higher in 2050 when respectively following the Regional, National or International Steering scenarios.</p

    The prevalence of triggers in paediatric migraine: a questionnaire study in 102 children and adolescents

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    The prevalence and characterization of migraine triggers have not been rigorously studied in children and adolescents. Using a questionnaire, we retrospectively studied the prevalence of 15 predefined trigger factors in a clinic-based population. In 102 children and adolescents fulfilling the Second Edition of The International Headache Classification criteria for paediatric migraine, at least one migraine trigger was reported by the patient and/or was the parents’ interpretation in 100% of patients. The mean number of migraine triggers reported per subject was 7. Mean time elapsed between exposure to a trigger factor and attack onset was comprised between 0 and 3 h in 88 patients (86%). The most common individual trigger was stress (75.5% of patients), followed by lack of sleep (69.6%), warm climate (68.6%) and video games (64.7%). Stress was also the most frequently reported migraine trigger always associated with attacks (24.5%). In conclusion, trigger factors were frequently reported by children and adolescents with migraine and stress was the most frequent

    A General Method for Targeted Quantitative Cross-Linking Mass Spectrometry

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    Chemical cross-linking mass spectrometry (XL-MS) provides protein structural information by identifying covalently linked proximal amino acid residues on protein surfaces. The information gained by this technique is complementary to other structural biology methods such as x-ray crystallography, NMR and cryo-electron microscopy[1]. The extension of traditional quantitative proteomics methods with chemical cross-linking can provide information on the structural dynamics of protein structures and protein complexes. The identification and quantitation of cross-linked peptides remains challenging for the general community, requiring specialized expertise ultimately limiting more widespread adoption of the technique. We describe a general method for targeted quantitative mass spectrometric analysis of cross-linked peptide pairs. We report the adaptation of the widely used, open source software package Skyline, for the analysis of quantitative XL-MS data as a means for data analysis and sharing of methods. We demonstrate the utility and robustness of the method with a cross-laboratory study and present data that is supported by and validates previously published data on quantified cross-linked peptide pairs. This advance provides an easy to use resource so that any lab with access to a LC-MS system capable of performing targeted quantitative analysis can quickly and accurately measure dynamic changes in protein structure and protein interactions
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