The Forms Things Want to Come As

Rather than take up the literary world’s on and off obsession with classifications and genre demarcations, this talk will center on the relationship between ideas, things, forms, and shapes — how writing can be a practice of, as poet A. R. Ammons once put it, looking for ‘the forms|things want to come as’. What does it mean for a thing to want to come as a form? What is the relationship between the content of an idea and its shape on the page? To examine such questions, Nelson will read from a variety of her works and think about how they relate (or don’t) to poet Robert Creeley’s famous contention, ‘form is never more than an extension of content’. Possible tributary lines of thought include: the literary nature of (some) philosophy; the question of ‘vernacular scholarship’ (a term coined by Eileen Myles), various strategies of performing the self in writing; and the value of never settling, of staying on the move. Maggie Nelson is the author of several acclaimed books of poetry and prose, including the forthcoming collection Like Love: Essays and Conversations (2024), the national bestseller On Freedom: Four Songs of Care and Constraint (2021), the National Book Critics Circle Award winner The Argonauts (2015), The Art of Cruelty: A Reckoning (2011), Bluets (2009; named by Bookforum as one of the top 10 best books of the past 20 years), The Red Parts (2007), Women, the New York School, and Other True Abstractions (2007), and Jane: A Murder (2005). In 2016 she received a MacArthur ‘genius’ Fellowship. She currently teaches at the University of Southern California and lives in Los Angeles, CA.Maggie Nelson, The Forms Things Want to Come As, lecture, reading, ICI Berlin, 12 July 2023, video recording, mp4, 51:20 <https://doi.org/10.25620/e230712

Jeep and its Commercialization: A History of an American Business

Undergraduat

A review of Bayesian belief network models as decision-support tools for wetland conservation : are water birds potential umbrella taxa?

10 pagesCreative approaches to identifying umbrella species hold promise for devising effective surrogates of ecological communities or ecosystems. However, mechanistic niche models that predict range or habitat overlap among species may yet lack development. We reviewed literature on taxon-centered Bayesian belief network (BBN) models to explore a novel approach to identify umbrella taxa identifying taxonomic groups that share the largest proportion of habitat requirements (i.e., states of important habitat variables) with other wetland-dependent taxa. We reviewed and compiled published literature to provide a comprehensive and reproducible account of the current understanding of habitat requirements for freshwater, wetland-dependent taxa using BBNs. We found that wetland birds had the highest degree of shared habitat requirements with other taxa, and consequently may be suitable umbrella taxa in freshwater wetlands. Comparing habitat requirements using a BBN approach to build species distribution models, this review also identified taxa that may not benefit from conservation actions targeted at umbrella taxa by identifying taxa with unique habitat requirements not shared with umbrellas. Using a standard node set that accurately and comprehensively represents the ecosystem in question, BBNs could be designed to improve identification of umbrella taxa. In wetlands, expert knowledge about hydrology, geomorphology and soils could add important information regarding physical landscape characteristics relevant to species. Thus, a systems-oriented framework may improve overarching inferences from BBNs and subsequent utility to conservation planning and management.Postprin

Improving Self-Care of Patients with Chronic Disease using Online Personal Health Record

Background Effective management of chronic diseases such as prostate cancer is important. Research suggests a tendency to use self-care treatment options such as over-the-counter (OTC) complementary medications among prostate cancer patients. The current trend in patient-driven recording of health data in an online Personal Health Record (PHR) presents an opportunity to develop new data-driven approaches for improving prostate cancer patient care. However, the ability of current online solutions to share patients’ data for better decision support is limited. An informatics approach may improve online sharing of self-care interventions among these patients. It can also provide better evidence to support decisions made during their self-managed care. Aims To identify requirements for an online system and describe a new case-based reasoning (CBR) method for improving self-care of advanced prostate cancer patients in an online PHR environment. Method A non-identifying online survey was conducted to understand self-care patterns among prostate cancer patients and to identify requirements for an online information system. The pilot study was carried out between August 2010 and December 2010. A case-base of 52 patients was developed. Results The data analysis showed self-care patterns among the prostate cancer patients. Selenium (55%) was the common complementary supplement used by the patients. Paracetamol (about 45%) was the commonly used OTC by the patients. Conclusion The results of this study specified requirements for an online case-based reasoning information system. The outcomes of this study are being incorporated in design of the proposed Artificial Intelligence (AI) driven patient journey browser system. A basic version of the proposed system is currently being considered for implementation

Trade and Global Value Chains Initiative: Mid-Term Evaluation Report

The Trade and Global Value Chains Initiative seeks to test whether investments in social upgrading (better working conditions and access to better work) can lead to business and development gains, and also ensure that better skilled, younger workers enter the sector and work more productively. Previous research indicated that companies do not invest in social upgrading because they lack both sufficient incentive to act on their own and convincing evidence of the benefits. Investment with other stakeholders in social upgrading could deliver business benefits and help to ensure the longer-term profitability and sustainability of corporate supply chains. A catalytic fund is the delivery mechanism (a modified challenge fund with technical advice provided to grantees), making public funds available to successful coalition applicants and leveraging private sector investment. The aim is to facilitate corporate behavioural change, benefitting workers/smallholders (social upgrading) and suppliers and retailers (economic upgrading). The TGVCI focuses on Ready Made Garments, Bangladesh, and horticulture in South Africa and Kenya. This report presents the Mid-Term Evaluation (MTE) of the TGVCI conducted by the Evaluation Management Unit (EMU). Twenty projects have been funded in two rounds. The Round 1 projects are nearing completion and Round 2 projects are still on-going. This slightly delayed implementation means that the evidence available and the analysis feasible at this stage are necessarily limited. The projects do nevertheless allow reasonable conclusions to be drawn on relevance, effectiveness and plausible impacts, provide initial findings on cost-effectiveness and indications on sustainability

Exposure to Household Air Pollution from Biomass Cookstoves and Blood Pressure Among Women in Rural Honduras: A Cross‐Sectional Study

Growing evidence links household air pollution exposure from biomass cookstoves with elevated blood pressure. We assessed cross‐sectional associations of 24‐hour mean concentrations of personal and kitchen fine particulate matter (PM2.5), black carbon (BC), and stove type with blood pressure, adjusting for confounders, among 147 women using traditional or cleaner‐burning Justa stoves in Honduras. We investigated effect modification by age and body mass index. Traditional stove users had mean (standard deviation) personal and kitchen 24‐hour PM2.5 concentrations of 126 μg/m3 (77) and 360 μg/m3 (374), while Justa stove users’ exposures were 66 μg/m3 (38) and 137 μg/m3(194), respectively. BC concentrations were similarly lower among Justa stove users. Adjusted mean systolic blood pressure was 2.5 mm Hg higher (95% CI, 0.7‐4.3) per unit increase in natural log‐transformed kitchen PM2.5 concentration; results were stronger among women of 40 years or older (5.2 mm Hg increase, 95% CI, 2.3‐8.1). Adjusted odds of borderline high and high blood pressure (categorized) were also elevated (odds ratio = 1.5, 95% CI, 1.0‐2.3). Some results included null values and are suggestive. Results suggest that reduced household air pollution, even when concentrations exceed air quality guidelines, may help lower cardiovascular disease risk, particularly among older subgroups

Study Protocol for a Stepped-Wedge Randomized Cookstove Intervention in Rural Honduras: Household Air Pollution and Cardiometabolic Health

Growing evidence links household air pollution exposure from biomass-burning cookstoves to cardiometabolic disease risk. Few randomized controlled interventions of cookstoves (biomass or otherwise) have quantitatively characterized changes in exposure and indicators of cardiometabolic health, a growing and understudied burden in low- and middle-income countries (LMICs). Ideally, the solution is to transition households to clean cooking, such as with electric or liquefied petroleum gas stoves; however, those unable to afford or to access these options will continue to burn biomass for the foreseeable future. Wood-burning cookstove designs such as the Justa (incorporating an engineered combustion zone and chimney) have the potential to substantially reduce air pollution exposures. Previous cookstove intervention studies have been limited by stove types that did not substantially reduce exposures and/or by low cookstove adoption and sustained use, and few studies have incorporated community-engaged approaches to enhance the intervention

Genome-wide chromatin accessibility, DNA methylation and gene expression analysis of histone deacetylase inhibition in triple-negative breast cancer.

Triple-negative breast cancer (TNBC), especially the subset with a basal phenotype, represents the most aggressive subtype of breast cancer. Unlike other solid tumors, TNBCs harbor a low number of driver mutations. Conversely, we and others have demonstrated a significant impact of epigenetic alterations, including DNA methylation and histone post-translational modifications, affecting TNBCs. Due to the promising results in pre-clinical studies, histone deacetylase inhibitors (HDACi) are currently being tested in several clinical trials for breast cancer and other solid tumors. However, the genome-wide epigenetic and transcriptomic implications of HDAC inhibition are still poorly understood. Here, we provide detailed information about the design of a multi-platform dataset that describes the epigenomic and transcriptomic effects of HDACi. This dataset includes genome-wide chromatin accessibility (assessed by ATAC-Sequencing), DNA methylation (assessed by Illumina HM450K BeadChip) and gene expression (assessed by RNA-Sequencing) analyses before and after HDACi treatment of HCC1806 and MDA-MB-231, two human TNBC cell lines with basal-like phenotype