Pattern formation on the surface of cationic-anionic cylindrical aggregates

Charged pattern formation on the surfaces of self--assembled cylindrical micelles formed from oppositely charged heterogeneous molecules such as cationic and anionic peptide amphiphiles is investigated. The net incompatibility $\chi$ among different components results in the formation of segregated domains, whose growth is inhibited by electrostatics. The transition to striped phases proceeds through an intermediate structure governed by fluctuations, followed by states with various lamellar orientations, which depend on cylinder radius $R_c$ and $\chi$. We analyze the specific heat, susceptibility $S(q^*)$, domain size $\Lambda=2\pi/q^*$ and morphology as a function of $R_c$ and $\chi$.Comment: Sent to PRL 11Jan05 Transferred from PRL to PRE 10Jun0

Maintaining Professional Face: Deceptive Impression Management in Community Sport Coaching

This article breaks new ground in the sociology of sports work through its novel exploration of workplace deception and the associated development of an original typology of deceptive impression management. Analysis of data collected from a two-phased research design, comprising online interviews and survey responses from 102 participants, revealed that community sport coaches employed deceptive impression management to display emotional control, an ideal practice of their work, and to feign expert knowledge. These types of deceptive impression management consisted of disguising disdain, flattering insincerely, camouflaging alternative approaches, covering-up mistakes, hiding a lack of expected knowledge, and reporting favourable metrics. Drawing on theories of dramaturgical analysis (Goffman, 1959, 1967, 1974) and emotional labour (Hochschild, 1979, 1983) as used in constructing a professional image, we examine how the coaches used deception to cope with challenging work circumstances that endanger projecting a professional appearance. The present article not only advances our sociological understanding of sports work but raises important questions for the preparation, development, and support of sports workers

An Assessment of Tire-Buying Among Millennial Consumers

This study first examines general purchasing trends among millennial consumers before digging into the perceptions that millennial consumers have of the tire-purchasing experience. Our initial hypothesis was that the negative view of tire-purchasing held by many millennial age consumers was driven by the difficulty of the process itself. Through our own research, we discovered that it is the perceptions held by those who have not yet purchased tires rather than the reality of the purchasing experience that is the issue

Planet migration: self-gravitating radiation hydrodynamical models of protoplanets with surfaces

We calculate radial migration rates of protoplanets in laminar minimum mass solar nebula discs using three-dimensional self-gravitating radiation hydrodynamical (RHD) models. The protoplanets are free to migrate, whereupon their migration rates are measured. For low mass protoplanets (10-50 M_\oplus) we find increases in the migration timescales of up to an order of magnitude between locally-isothermal and RHD models. In the high-mass regime the migration rates are changed very little. These results are arrived at by calculating migration rates in locally-isothermal models, before sequentially introducing self-gravity, and radiative transfer, allowing us to isolate the effects of the additional physics. We find that using a locally-isothermal equation of state, without self-gravity, we reproduce the migration rates obtained by previous analytic and numerical models. We explore the impact of different protoplanet models, and changes to their assumed radii, upon migration. The introduction of self-gravity gives a slight reduction of the migration rates, whilst the inertial mass problem, which has been proposed for high mass protoplanets with circumplanetary discs, is reproduced. Upon introducing radiative transfer to models of low mass protoplanets (\approx 10 M_\oplus), modelled as small radius accreting point masses, we find outward migration with a rate of approximately twice the analytic inward rate. However, when modelling such a protoplanet in a more realistic manner, with a surface which enables the formation of a deep envelope, this outward migration is not seen.Comment: 21 pages, 21 figure

Repairing relationship conflict in community sport work: “Offender” perspectives

Through our investigation of relationship conflict and repair in community sport coaching this article makes a novel contribution to the sociology of sport work. Such inquiry is necessary as interpersonal conflict has the potential to erode worker commitment, engagement, performance, satisfaction, and mental health. To date, the study of interpersonal conflict in coaching has been framed psychologically. It is our position that sociologically inspired inquiry is not only necessary but can valuably contribute to academic debate in this area. To redress this situation we conducted in-depth, semi-structured, interviews with 18 community sport coaches to produce rich insights into the participants’ (transgressors) understandings of fractured workplace relations, remedial work used to repair and restore relationships, as well as desirable and undesirable consequences emanating from these restorative efforts. Through our application of Ren and Gray’s and Goffman’s theorization addressing restoration mechanismsthe present study extends existing understanding by detailing how a) relationship conflict was triggered by the participants having violated the identity and control of significant working others, b) participants attempted to repair relations by offering accounts, apologies, and demonstrations of concern, and c) the success of these restorative efforts was variable and dependent on their being accepted by the offended parties. It is our hope that these original empirical and theoretical insights not only advance understanding about relationship conflict and repair but prompt further sociologically inspired research into this important interpersonal aspect of sport work

Geometrical Defects in Josephson Junction Arrays

Dislocations and disclinations in a lattice of Josephson junctions will affect the dynamics of vortex excitations within the array. These defects effectively distort the space in which the excitations move and interact. The interaction energy between such defects and excitations are determined and vortex trajectories in twisted lattices are calculated. Finally, possible experiments observing these effects are presented.Comment: 26 pages including 5 figure

Transformation of alignment files improves performance of variant callers for long-read RNA sequencing data

Long-read RNA sequencing (lrRNA-seq) produces detailed information about full-length transcripts, including novel and sample-specific isoforms. Furthermore, there is an opportunity to call variants directly from lrRNA-seq data. However, most state-of-the-art variant callers have been developed for genomic DNA. Here, there are two objectives: first, we perform a mini-benchmark on GATK, DeepVariant, Clair3, and NanoCaller primarily on PacBio Iso-Seq, data, but also on Nanopore and Illumina RNA-seq data; second, we propose a pipeline to process spliced-alignment files, making them suitable for variant calling with DNA-based callers. With such manipulations, high calling performance can be achieved using DeepVariant on Iso-seq data

Fish and chips: Various methodologies demonstrate utility of a 16,006-gene salmonid microarray

BACKGROUND: We have developed and fabricated a salmonid microarray containing cDNAs representing 16,006 genes. The genes spotted on the array have been stringently selected from Atlantic salmon and rainbow trout expressed sequence tag (EST) databases. The EST databases presently contain over 300,000 sequences from over 175 salmonid cDNA libraries derived from a wide variety of tissues and different developmental stages. In order to evaluate the utility of the microarray, a number of hybridization techniques and screening methods have been developed and tested. RESULTS: We have analyzed and evaluated the utility of a microarray containing 16,006 (16K) salmonid cDNAs in a variety of potential experimental settings. We quantified the amount of transcriptome binding that occurred in cross-species, organ complexity and intraspecific variation hybridization studies. We also developed a methodology to rapidly identify and confirm the contents of a bacterial artificial chromosome (BAC) library containing Atlantic salmon genomic DNA. CONCLUSION: We validate and demonstrate the usefulness of the 16K microarray over a wide range of teleosts, even for transcriptome targets from species distantly related to salmonids. We show the potential of the use of the microarray in a variety of experimental settings through hybridization studies that examine the binding of targets derived from different organs and tissues. Intraspecific variation in transcriptome expression is evaluated and discussed. Finally, BAC hybridizations are demonstrated as a rapid and accurate means to identify gene content

Scaling of the buckling transition of ridges in thin sheets

When a thin elastic sheet crumples, the elastic energy condenses into a network of folding lines and point vertices. These folds and vertices have elastic energy densities much greater than the surrounding areas, and most of the work required to crumple the sheet is consumed in breaking the folding lines or ``ridges''. To understand crumpling it is then necessary to understand the strength of ridges. In this work, we consider the buckling of a single ridge under the action of inward forcing applied at its ends. We demonstrate a simple scaling relation for the response of the ridge to the force prior to buckling. We also show that the buckling instability depends only on the ratio of strain along the ridge to curvature across it. Numerically, we find for a wide range of boundary conditions that ridges buckle when our forcing has increased their elastic energy by 20% over their resting state value. We also observe a correlation between neighbor interactions and the location of initial buckling. Analytic arguments and numerical simulations are employed to prove these results. Implications for the strength of ridges as structural elements are discussed.Comment: 42 pages, latex, doctoral dissertation, to be submitted to Phys Rev

Risk Communication for Viral Hepatitis Management Among Migrants

The burden of viral hepatitis is high with huge mortality and morbidity on human population. The increasing migration of people from areas highly prevalent of viral hepatitis poses a unique threat to the healthcare systems of the host nations. The deficient universal standards for screening, vaccination, and treatment of viral hepatitis have therefore made the burden of chronic liver disease and hepatocellular carcinoma to increase among migrant populations globally. This study examines the role of risk communication in managing viral hepatitis among migrants at the different levels of pre-departure phase, travel phase, destination phase, interception phase and the return phase. The study concluded on the need for concerted effort by national governments to develop a national communication policy with comprehensive risk communication strategies on viral hepatitis management among migrant