173 research outputs found
Advantageous Attacks: The Role of Advantage in Targeting People Under the Law of Armed Conflict
Examining the effects of fear of failure, self-efficacy and gender role conflict in male and female engineering students
The field of engineering continues to have significantly fewer women engineers than men. Engineering has long been considered to be a male dominated career, with fewer women receiving bachelor\u27s degrees in engineering and gaining employment in the engineering field. The present study was an attempt to determine influencing factors that discourage women from pursuing engineering as an educational and career choice. The current study examined gender role conflict, self-efficacy, and fear of failure as potential factors influencing women\u27s preferences to pursue an engineering degree. Both male and female genders were participants in the research to determine gender differences for these factors. All participants were students majoring in the engineering discipline. In the current study, the Gender Role Conflict Scale (GRCS), the Performance Failure Appraisal Inventory (PFAI), and The Longitudinal Assessment of Engineering Self-Efficacy (LAESE) were analyzed. An additional instrument was designed to rate potential engineering student applicants based on their individual qualities and attributes that are important for successful engineers. Results indicated that females reported higher incidence of fear for their future in the engineering field, fear of being embarrassed or shamed in front of others, and fear of self-devaluation regarding their capabilities as an engineer. Results also indicated males reported higher levels of self-efficacy for mathematics in regard to their skill and abilities as engineers. There was no support for hypotheses that predicted females would be rated less desirably as future engineers based upon their gender, skills, and capabilities
Protecting Confidential Investigations or Gagging the Press? Freedom of Expression and Interference with the Administration of Justice at the Extraordinary Chambers in the Courts of Cambodia
“Like Wolves in Sheep’s Clothing”: Combating Racial Bias in Washington State’s Criminal Justice System
Despite their differences, both the majority and concurring opinions in Monday present new ways to address prosecutorial misconduct, deter the injection of racial bias into courtroom proceedings, and create substantively similar outcomes. Part II of this Note discusses the traditional prosecutorial misconduct test in Washington State, as well as the rules articulated by the Monday majority and concurrence. Part III discusses the implications of both the majority and concurring opinions, the primary differences in their approaches to deterrence, the degree of racial bias they require to warrant reversal of a conviction, and the discretion they afford the judiciary. Part III also suggests that courts must consider both the rights of criminal defendants and the aggregate impacts of racial bias on society at large when fashioning a rule to combat racial bias
Leveraging Heritrix and the Wayback Machine on a Corporate Intranet: A Case Study on Improving Corporate Archives
In this work, we present a case study in which we investigate using open-source, web-scale web archiving tools (i.e., Heritrix and the Wayback Machine installed on the MITRE Intranet) to automatically archive a corporate Intranet. We use this case study to outline the challenges of Intranet web archiving, identify situations in which the open source tools are not well suited for the needs of the corporate archivists, and make recommendations for future corporate archivists wishing to use such tools. We performed a crawl of 143,268 URIs (125 GB and 25 hours) to demonstrate that the crawlers are easy to set up, efficiently crawl the Intranet, and improve archive management. However, challenges exist when the Intranet contains sensitive information, areas with potential archival value require user credentials, or archival targets make extensive use of internally developed and customized web services. We elaborate on and recommend approaches for overcoming these challenges. [ABSTRACT FROM AUTHOR
Sunlight-mediated inactivation of health-relevant microorganisms in water: a review of mechanisms and modeling approaches.
Health-relevant microorganisms present in natural surface waters and engineered treatment systems that are exposed to sunlight can be inactivated by a complex set of interacting mechanisms. The net impact of sunlight depends on the solar spectral irradiance, the susceptibility of the specific microorganism to each mechanism, and the water quality; inactivation rates can vary by orders of magnitude depending on the organism and environmental conditions. Natural organic matter (NOM) has a large influence, as it can attenuate radiation and thus decrease inactivation by endogenous mechanisms. Simultaneously NOM sensitizes the formation of reactive intermediates that can damage microorganisms via exogenous mechanisms. To accurately predict inactivation and design engineered systems that enhance solar inactivation, it is necessary to model these processes, although some details are not yet sufficiently well understood. In this critical review, we summarize the photo-physics, -chemistry, and -biology that underpin sunlight-mediated inactivation, as well as the targets of damage and cellular responses to sunlight exposure. Viruses that are not susceptible to exogenous inactivation are only inactivated if UVB wavelengths (280-320 nm) are present, such as in very clear, open waters or in containers that are transparent to UVB. Bacteria are susceptible to slightly longer wavelengths. Some viruses and bacteria (especially Gram-positive) are susceptible to exogenous inactivation, which can be initiated by visible as well as UV wavelengths. We review approaches to model sunlight-mediated inactivation and illustrate how the environmental conditions can dramatically shift the inactivation rate of organisms. The implications of this mechanistic understanding of solar inactivation are discussed for a range of applications, including recreational water quality, natural treatment systems, solar disinfection of drinking water (SODIS), and enhanced inactivation via the use of sensitizers and photocatalysts. Finally, priorities for future research are identified that will further our understanding of the key role that sunlight disinfection plays in natural systems and the potential to enhance this process in engineered systems
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Metabolite Responsive Nanoparticle-Protein Complex
Stimuli responsive polymers are an efficient means of targeted therapy.  Compared to conventional agents, they increase bioavailability and efficacy.  In particular, polymer hydrogel nanoparticles (NPs) can be designed to respond when exposed to a specific environmental stimulus such as pH or temperature. However, targeting a specific metabolite as the trigger for stimuli response could further elevate selectivity and create a new class of bioresponsive materials.  In this work we describe an N-isopropylacrylamide (NIPAm) NP that responds to a specific metabolite characteristic of a hypoxic environment found in cancerous tumors.  NIPAm NPs were synthesized by copolymerization with an oxamate derivative, a known inhibitor of lactate dehydrogenase (LDH).  The oxamate functionalized NPs (OxNP) efficiently sequestered LDH to produce an OxNP-protein complex.  When exposed to elevated concentrations of lactic acid, a substrate of LDH and a metabolite characteristic of hypoxic tumor microenvironments, OxNP-LDH complexes swelled (65%). The OxNP-LDH complexes were not responsive to structurally related small molecules. This work demonstrates a proof of concept for tuning NP responsiveness by conjugation with a key protein to target a specific metabolite of disease
Enhancing Vitality in Academic Medicine: Faculty Development and Productivity
The prevalence of low satisfaction and increased stress among faculty in academic medicine makes understanding facuity vitality in this field more important than ever before. To explore the contributors to and outcomes of faculty vitality, we conducted a multi-institutional study of faculty in academic medicine (N = 1,980, 42 percent response rate). Faculty were surveyed about climate and leadership, career and life management, satisfaction, engagement, productivity, and involvement in faculty development. Analysis reveals that controlling for other factors, academic medicine faculty who participate regularly in facuity development activ ities are significantly more satisfied, engaged, and productive
Behavioral responses of the endemic shrimp Halocardina rubra (Malacostraca:Atyidae) to an introduced fish, Gambusia affinis (Actinopterygii: Poeciliidae) and implications for the trophic structure of Hawaiian anchialine ponds
In the Hawaiian Islands, intentionally introduced exotic fishes have been linked to changes in native biodiversity and community composition. In 1905, the mosquito fish Gambusia affinis was introduced to control mosquitoes. Subsequently, G. affinis spread throughout the Islands and into coastal anchialine ponds. Previous studies suggest that presence of invasive fishes in anchialine ponds may eliminate native species, including the endemic shrimp Halocaridina rubra. We examined effects of G. affinis on H. rubra populations in anchialine ponds on the Kona-Kohala coast of the island of Hawai/i. In the presence of G. affinis, H. rubra exhibited a diel activity pattern that was not seen in fishless ponds. Shrimp in ponds with fish were active only at night. This pattern was evident in anchialine ponds and in laboratory experiments. In laboratory predation experiments, G. affinis preferentially consumed smaller H. rubra, and in the field the H. rubra collected from invaded sites were larger than those from fishless ponds. Analysis of trophic position using stable isotope analyses showed that feeding of H. rubra was not significantly distinct from that of snails, assumed to feed at trophic level 2.0 on epilithic algae, but G. affinis was slightly omnivorous, feeding at tropic level 2.2. The mosquito fish diet was apparently composed primarily of algae when the defensive behavior of H. rubra made them substantially unavailable as prey. The effect of successful establishment of G. affinis on shrimp behavior has the potential to alter abundance of benthic algae and processing and recycling of nutrients in anchialine pond ecosystems
Alexa?: Possibilities of Voice Assistant Technology and Artificial Intelligence in the Classroom
The following paper represents the combined effort of 10 educators exploring the experience and use of voice assistant technology in classrooms. This reflection and study of our classrooms looks to better understand both our use of technology and students’ use of technology in very specific ways. Is there a place for voice assistant technology in our classrooms? What benefits are there? What obstacles exist? We tell our stories and experiences here with the intent to provide context and continue the discussion among more of our colleagues
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