Концепт «природа» в виртуальном дискурсе сферы природопользования (на материале русского и английского языков)

Объектом исследования является концепт "природа" в виртуальном дискурсе сферы природопользования на английском и русском языках. Предметом исследования представлены языковые средства концепта "природа" в русском и английском языках. Цель работы – выявление семантических особенностей реализации концепта "природа" на материале сайтов в сфере природопользования на русском и английском языках. В процессе исследования были рассмотрены такие понятия, как концепт, языковая картина мира, научная картина мира, дискурс, дискурсивная картина мира, проанализированы семантические особенности концепта "природа" в русском и английском языках.The object of the research is the concept “nature” in virtual discourse in environmental management sphere in Russian and in English. The subject of the research is linguistic means representing the concept “nature” in Russian and English. The aim is to identify semantic features of verbalization of the concept “nature” in texts of virtual environmental management discourse in Russian and in English. During the research process, the following terms have been considered: concept, linguistic view of the world, scientific view of the world, discourse, discursive view of the world. Semantic features of the linguistic means representing the concept “nature” in Russian and in English have been analyzed

Influência do tratamento intensivo com suporte de peso corporal na função motora de crianças com paralisia cerebral

A aquisição da marcha sob o aspecto neuromotor da reabilitação vem a ser o principal desígnio do terapeuta durante a elaboração do plano de tratamento do paciente com paralisia cerebral, uma vez que a marcha representa não só um ganho da habilidade de locomover-se, mas também um conjunto de reações e padrões de movimento que auxiliam na função motora. Objetivo: Analisar os efeitos de um tratamento intensivo por meio do suporte de peso corporal em crianças com paralisia cerebral. Métodos: Participaram do estudo 10 crianças com paralisia cerebral, GMFCS nível IV ou V, idade entre 4 a 9 anos. Onde foram realizadas sessões diárias com suporte de peso corporal em esteira ergométrica com auxílio de terapeutas para executar o padrão de marcha mais próximo da normalidade, com pontos chaves em joelho e tornozelo com duração de 30 minutos de tratamento e intervalo de 24 horas, por um período de 10 dias. Para fins de avaliação pré e pós-intervenção, utilizando a escala de medição da função motora grossa GMFM, e da flexibilidade pelo Flexiteste. Resultados: Foi possível constatar um aumento relevante na função motora grossa dos sujeitos, onde o domínio Deitar e Rolar obteve maior pontuação, com um aumento de 10,77%. Sentar demonstrou aumento de 3,80%, Engatinhar e Ajoelhar 6,43% e o domínio Em Pé 3,45%. Relativo ao Flexiteste, a média entre os sujeitos relatou aumento expressivo de 4,2 pontos. Já em análise individual, percebe-se que 3 indivíduos obtiveram aumento de score de 6 pontos. Conclusão: Um protocolo intensivo de curta duração é capaz de trazer ganhos de flexibilidade e motores rápidos a crianças que possuem quadro de paralisia cerebral.The acquisition of gait under the neuromotor aspect of rehabilitation is the main goal of the therapist during the elaboration of the treatment plan of the patient with cerebral palsy, since gait represents not only a gain in the ability to move, but also a set of reactions and movement patterns that aid in motor function. Objective: To analyze the effects of intensive treatment by means of body weight support in children with cerebral palsy. Method: Ten children with cerebral palsy, GMFCS level IV or V, age between 4 and 9 years participated in the study. Where daily sessions were performed with body weight support on a treadmill with the help of therapists to perform the walking pattern closest to normal, with key points in the knee and ankle lasting 30 minutes of treatment and 24 hour intervals for one period of 10 days. For purposes of pre and post-intervention evaluation, using the GMFM gross motor function measurement scale, and Flexitest flexibility. Results: It was possible to observe a significant increase in the gross motor function of the subjects, where the lie down and roll domain obtained a higher score, with an increase of 10.77%. To sit demonstrated a 3.80% increase, Crawling and Kneeling 6.43% and the Standing Foot 3.45%. Relative to Flexitest, the mean between subjects reported a significant increase of 4.2 points. In the individual analysis, it was observed that 3 subjects had a 6-point score increase. Conclusions: An intensive short-duration protocol is capable of bringing flexibility gains and fast motor to children with cerebral palsy

Ultrasonic intensification as a tool for enhanced microbial biofuel yields

peer-reviewedUltrasonication has recently received attention as a novel bioprocessing tool for process intensification in many areas of downstream processing. Ultrasonic intensification (periodic ultrasonic treatment during the fermentation process) can result in a more effective homogenization of biomass and faster energy and mass transfer to biomass over short time periods which can result in enhanced microbial growth. Ultrasonic intensification can allow the rapid selective extraction of specific biomass components and can enhance product yields which can be of economic benefit. This review focuses on the role of ultrasonication in the extraction and yield enhancement of compounds from various microbial sources, specifically algal and cyanobacterial biomass with a focus on the production of biofuels. The operating principles associated with the process of ultrasonication and the influence of various operating conditions including ultrasonic frequency, power intensity, ultrasonic duration, reactor designs and kinetics applied for ultrasonic intensification are also described

Análisis sensorial de mate frío (tereré) de jugo artificial sabor naranja mediante estadística de supervivencia

Se realizó un ensayo de aceptabilidad sensorial para determinar la concentración óptima de jugo para preparar mate frío o tereré y un análisis descriptivo para estudiar la variación de la intensidad de cuatro descriptores seleccionados durante el consumo del tereré. Los resultados del análisis descriptivo fueron correlacionados con los valores de sólidos solubles obtenidos mediante la simulación del consumo del mate frío. Para la determinación de la concentración óptima de jugo se realizó un ensayo de aceptabilidad con consumidores, y los datos fueron analizados con herramientas de estadística de supervivencia. La concentración óptima de jugo fue de 6,38 ± 0,62g/L, que corresponde a un 22,87% de consumidores que rechazan la muestra. El ensayo descriptivo indicó que en los primeros tererés predomina el sabor del jugo y que posteriormente el sabor a yerba mate se intensifica gradualmente. Los coeficientes de correlación lineal entre los puntajes asignados a los descriptores sensoriales y las concentraciones de sólidos solubles de la simulación del consumo del mate sugieren que deben realizarse otros análisis representativos de la muestra a fin de establecer correlaciones más significativas.A sensory acceptance test to determine the optimum concentration of artificial orange juice to prepare cold mate or tereré was performed, and a descriptive analysis to study the variation of four selected descriptors during tereré consumption was done. The results of the descriptive analysis were correlated with soluble solids values of a simulated cold mate consumption. Optimum juice concentration was determined by an acceptability test, and data were analyzed with survival statistics tools. The optimum concentration was 6.38 ± 0.62 g/L, which matches to 22.87% of consumers rejecting the sample. The descriptive test indicated that, in the first tereré, the juice descriptors prevailed, and the yerba mate descriptors gradually intensified with successive tererés. Linear correlation coefficients found between sensory descriptors scores and soluble solids concentrations in the simulated consumption suggest that other representative determinations should be done to find more significant correlationsFil: Neis, Emiliano Roberto. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; ArgentinaFil: Covinich, Monica Mariela. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; ArgentinaFil: Scipioni, Griselda Patricia. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales; Argentin

Análisis sensorial de mate frío (tereré) de jugo artificial sabor naranja mediante estadística de supervivencia

A sensory acceptance test to determine the optimum concentration of artificial orange juice to prepare cold mate or tereré was performed, and a descriptive analysis to study the variation of four selected descriptors during tereré consumption was done. The results of the descriptive analysis were correlated with soluble solids values of a simulated cold mate consumption. Optimum juice concentration was determined by an acceptability test, and data were analyzed with survival statistics tools. The optimum concentration was 6.38 ± 0.62 g/L, which matches to 22.87% of consumers rejecting the sample. The descriptive test indicated that, in the first tereré, the juice descriptors prevailed, and the yerba mate descriptors gradually intensified with successive tererés. Linear correlation coefficients found between sensory descriptors scores and soluble solids concentrations in the simulated consumption suggest that other representative determinations should be done to find more significant correlations.Se realizó un ensayo de aceptabilidad sensorial para determinar la concentración óptima de jugo para preparar mate frío o tereré y un análisis descriptivo para estudiar la variación de la intensidad de cuatro descriptores seleccionados durante el consumo del tereré. Los resultados del análisis descriptivo fueron correlacionados con los valores de sólidos solubles obtenidos mediante la simulación del consumo del mate frío. Para la determinación de la concentración óptima de jugo se realizó un ensayo de aceptabilidad con consumidores, y los datos fueron analizados con herramientas de estadística de supervivencia. La concentración óptima de jugo fue de 6,38 ± 0,62 g/L, que corresponde a un 22,87% de consumidores que rechazan la muestra. El ensayo descriptivo indicó que en los primeros tererés predomina el sabor del jugo y que posteriormente el sabor a yerba mate se intensifica gradualmente. Los coeficientes de correlación lineal entre los puntajes asignados a los descriptores sensoriales y las concentraciones de sólidos solubles de la simulación del consumo del mate sugieren que deben realizarse otros análisis representativos de la muestra a fin de establecer correlaciones más significativas

Reconversion of experimental classes of Analytical Chemistry due to the ASPO

En este trabajo se presentan los ajustes realizados en la cátedra de Química Analítica para reconvertir las clases presenciales en clases remotas en el contexto de la pandemia por el COVID-19. El principal desafío fue desarrollar las clases prácticas de laboratorio en forma remota y aun así, promover la adquisición de destrezas y habilidades en el manejo de los instrumentos de laboratorio. Cada trabajo práctico se acompañó de una explicación teórica en formato digitalizado con imágenes secuenciadas y un hipervínculo con videos demostrativos de las partes más significativas de la experiencia dentro del laboratorio. Cada clase conto con un espacio de consulta sincrónica favoreciendo la retroalimentación. Se realizaron evaluaciones formativas utilizando los recursos disponibles en el aula virtual. Este tiempo de ASPO significó para los docentes un aprendizaje intenso que sirvió para reposicionarse y repensar las prácticas, considerando modalidades de enseñanza mixtas en la postpandemia.This work presents the modications that were made in the Analytical Chemistry course to change the classroom lessons into remote ones in the context of the COVID-19 pandemic. The main challenge was to develop practical laboratory classes remotely and yet promote the acquisition of skills and abilities in the handling of laboratory instruments. Each practical work was accompanied by a theoretical explanation in digital format, which contained a brief introduction and a hyperlink with short demonstrative videos for the most remarkable parts of the laboratory experiments. Formative assessments were made using the multiple-choice resource of the virtual classroom. This time of ASPO meant intense learning for the professors, which allowed them to reposition themselves and rethink teaching practices, considering mixed teaching modalities for the post-pandemic.Fil: Baumann, Alicia Jeannette. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales; ArgentinaFil: Scipioni, Griselda Patricia. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales; ArgentinaFil: Sadañoski, Marcela Alejandra. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; ArgentinaFil: Neis, Emiliano Roberto. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste; ArgentinaFil: Acuña, Miriam Gladys. Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales; Argentin

Leucoselect Phytosome Modulates Serum Eicosapentaenoic Acid, Docosahexaenoic Acid, and Prostaglandin E3 in a Phase I Lung Cancer Chemoprevention StudyEffects of Grape Seed Extract on Complex Lipid Metabolomics

Grape seed procyanidin extract (GSE) has been shown to exert antineoplastic properties in preclinical studies. Recently, we reported findings from a modified phase I, open-label, dose escalation clinical study conducted to evaluate the safety, tolerability, MTD, and potential chemopreventive effects of leucoselect phytosome, a standardized GSE complexed with soy phospholipids to enhance bioavailability, in heavy active and former smokers. Three months of leucoselect phytosome treatment significantly decreased bronchial Ki-67 labeling index (LI), a marker of cell proliferation on the bronchial epithelium. Because GSE is widely used as a supplement to support cardiovascular health, we evaluate the impact of oral leucoselect phytosome on the fasting serum complex lipid metabolomics profiles in our participants. One month of leucoselect phytosome treatment significantly increased eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), the omega-3 polyunsaturated fatty acids (n-3 PUFA) with well-established anticancer properties. Leucoselect phytosome also significantly increased unsaturated phosphatidylcholines (PC), likely from soy phospolipids in the phytosome and functioning as transporters for these PUFAs. Furthermore, 3-month leucoselect phytosome treatment significantly increased serum prostaglandin (PG) E3 (PGE3), a metabolite of EPA with anti-inflammatory and antineoplastic properties. Such increases in PGE3 correlated with reductions of bronchial Ki-67 LI (r = -0.9; P = 0.0374). Moreover, posttreatment plasma samples from trial participants significantly inhibited proliferation of human lung cancer cell lines A549 (adenocarcinoma), H520 (squamous cell carcinoma), DMS114 (small cell carcinoma), and 1198 (preneoplastic cell line). Our findings further support the potential utility of leucoselect phytosome in reducing cardiovascular and neoplastic risks in heavy former and active smokers. PREVENTION RELEVANCE: In this correlative study of leucoselect phytosome for lung cancer chemoprevention in heavy active and former smokers, we demonstrate for the first time, favorable modulations of n-3PUFA and downstream PGE3 in fasting serum, further supporting the chemopreventive potential of leucoselect phytosome against lung cancer

A Pilot Study of a Grape Seed Procyanidin Extract for Lung Cancer Chemoprevention

Grape seed procyanidin extract (GSE) had been reported to exert antineoplastic properties in preclinical studies. A modified phase I, open-label, dose-escalation clinical study was conducted to evaluate the safety, tolerability, MTD, and potential chemopreventive effects of leucoselect phytosome (LP), a standardized GSE complexed with soy phospholipids to enhance bioavailability, in heavy active and former smokers. Eight subjects ages 46-68 years were enrolled into the study and treated with escalating oral doses of LP for 3 months. Bronchoscopies with bronchoalveolar lavage and bronchial biopsies were performed before and after 3 months of LP treatment. Hematoxylin and eosin stain for histopathology grading and IHC examination for Ki-67 proliferative labeling index (Ki-67 LI) were carried out on serially matched bronchial biopsy samples from each subject to determine responses to treatment. Two subjects were withdrawn due to issues unrelated to the study medication, and a total of 6 subjects completed the full study course. In general, 3 months of LP, reaching the highest dose per study protocol was well tolerated and no dosing adjustment was necessary. Such a treatment regimen significantly decreased bronchial Ki-67 LI by an average of 55% (P = 0.041), with concomitant decreases in serum miR-19a, -19b, and -106b, which were oncomirs previously reported to be downregulated by GSE, including LP, in preclinical studies. In spite of not reaching the original enrollment goal of 20, our findings nonetheless support the continued clinical translation of GSE as an antineoplastic and chemopreventive agent against lung cancer