Investigating Dielectric Properties of Sintered Polymers for Rapid Manufacturing

Selective Laser Sintering (SLS) of polymers is the leading technology in the growing field of Rapid Manufacturing. High Speed Sintering (HSS) is a process that offers the potential to reduce costs and processing times and thus open significant new markets for Rapid Manufactured parts. Much academic research has been performed with respect to mechanical properties of Rapid Manufactured parts, however the area of electrical properties has received little attention to date. Electrical properties are obviously important in applications that will involve embedding of circuits with Rapid Manufactured 3D objects. However electrical properties are also important for a wide variety of electrical products where Rapid Manufactured parts can be used as housings etc. This paper focuses on the dielectric properties of parts made by SLS and HSS and compares properties with those for conventionally processed polymers. Dielectric strength results show that SLS parts are comparable with injection moulded parts, while HSS parts are inferior to SLS parts. Dielectric constant and dissipation factor results show that HSS parts are comparable with injection moulded parts, whilst SLS parts have superior properties. The presence of porosity (SLS and HSS) and the presence of carbon (HSS) are suggested as reasons behind the variation in dielectric properties when compared with injection moulded parts.Mechanical Engineerin

SPEAR-1: An experiment to measure current collection in the ionosphere by high voltage biased conductors

An experiment is described in which a high electrical potential difference, up to 45 kV, was applied between deployed conducting spheres and a sounding rocket in the ionosphere. Measurements were made of the applied voltage and the resulting currents for each of 24 applications of different high potentials. In addition, diagnostic measurements of optical emissions in the vicinity of the spheres, energetic particle flow to the sounding rocket, dc electric field and wave data were made. The ambient plasma and neutral environments were measured by a Langmuir probe and a cold cathode neutral ionization gauge, respectively. The payload is described and examples of the measured current and voltage characteristics are presented. The characteristics of the measured currents are discussed in terms of the diagnostic measurements and the in-situ measurements of the vehicle environment. In general, it was found that the currents observed were at a level typical of magnetically limited currents from the ionospheric plasma for potentials less than 12 kV, and slightly higher for larger potentials. However, due to the failure to expose the plasma contactor, the vehicle sheath modified the sphere sheaths and made comparisons with the analytic models of Langmuir-Blodgett and Parker-Murphy less meaningful. Examples of localized enhancements of ambient gas density resulting from the operation of the attitude control system thrusters (cold nitrogen) were obtained. Current measurements and optical data indicated localized discharges due to enhanced gas density that reduced the vehicle-ionosphere impedance

Regulator of G-Protein Signalling-14 (RGS14) Regulates the Activation of αMβ2 Integrin during Phagocytosis

Integrin-mediated phagocytosis, an important physiological activity undertaken by professional phagocytes, requires bidirectional signalling to/from αMβ2 integrin and involves Rap1 and Rho GTPases. The action of Rap1 and the cytoskeletal protein talin in activating αMβ2 integrins, in a RIAM-independent manner, has been previously shown to be critical during phagocytosis in mammalian phagocytes. However, the events downstream of Rap1 are not clearly understood. Our data demonstrate that one potential Rap1 effector, Regulator of G-Protein Signalling-14 (RGS14), is involved in activating αMβ2. Exogenous expression of RGS14 in COS-7 cells expressing αMβ2 results in increased binding of C3bi-opsonised sheep red blood cells. Consistent with this, knock-down of RGS14 in J774.A1 macrophages results in decreased association with C3bi-opsonised sheep red blood cells. Regulation of αMβ2 function occurs through the R333 residue of the RGS14 Ras/Rap binding domain (RBD) and the F754 residue of β2, residues previously shown to be involved in binding of H-Ras and talin1 head binding prior to αMβ2 activation, respectively. Surprisingly, overexpression of talin2 or RAPL had no effect on αMβ2 regulation. Our results establish for the first time a role for RGS14 in the mechanism of Rap1/talin1 activation of αMβ2 during phagocytosis

Sourcing Innovation in the Digital Age

This paper introduces a recent innovation survey, the first of its kind in the Digital Age. With coverage of 300 large firms, sampled to be representative of corporate innovation in eight countries, the survey provides a unique look at how innovation, particularly digital innovation, is being sourced by firms around the world. We find that open innovation at these companies is pervasive, but also recent. Only in the 2010s have many firms started innovating with external partners like universities, third-party experts, startups, or crowd. Overwhelmingly, firms use these new external innovation sources for digital technologies where they have internal capability shortfalls. Despite the remarkable growth in the use of external innovation sources, internal innovation sources remain more important for companies. These internal sources also produce the projects most likely to provide a competitive advantage

Safe functional reactive programming through dependent types

Functional Reactive Programming (FRP) is an approach to reactive programming where systems are structured as networks of functions operating on signals. FRP is based on the synchronous dataflow paradigm and supports both continuous-time and discrete-time signals (hybrid systems).What sets FRP apart from most other languages for similar applications is its support for systems with dynamic structure and for higher-order reactive constructs. Statically guaranteeing correctness properties of programs is an attractive proposition. This is true in particular for typical application domains for reactive programming such as embedded systems. To that end, many existing reactive languages have type systems or other static checks that guarantee domain-specific properties, such as feedback loops always being well-formed. However, they are limited in their capabilities to support dynamism and higher-order data-flow compared with FRP. Thus, the onus of ensuring such properties of FRP programs has so far been on the programmer as established static techniques do not suffice. In this paper, we show how dependent types allow this concern to be addressed. We present an implementation of FRP embedded in the dependently-typed language Agda, leveraging the type system of the host language to craft a domain-specific (dependent) type system for FRP. The implementation constitutes a discrete, operational semantics of FRP, and as it passes the Agda type, coverage, and termination checks, we know the operational semantics is total, which means our type system is safe

Quantification of Field Resistance to Verticillium dahliae in Eight Russet-Skinned Potato Cultivars Using Real-Time PCR

Abstract Changes in potato production over the past 10 to 20 years, have resulted in increased emphasis being placed on breeding for resistance to Verticillium wilt, caused by Verticillium dahliae Kleb. While many russet-skinned cultivars recently have been released with reported resistance to Verticillium wilt, information is lacking on the level of pathogen colonization, and therefore, the level of true genetic resistance is not known. Eight russet-skinned cultivars were grown in field trials with low and high levels of V. dahliae in the soil, and evaluated for wilt, stem colonization, yield, and tuber vascular discoloration. A recently developed QPCR assay was validated, with strong relationships to culture plating assays over three stem sampling dates. Additionally, stem colonization levels, as determined by QPCR, were related to wilt and tuber vascular discoloration. However, total yield did not exhibit a strong relationship to any other parameter evaluated in this study. Results from these studies indicate that varying levels of true resistance are present in the russet-skinned cultivars evaluated, and that the QPCR assay can be reliable in rapidly evaluating resistance to V. dahliae under field conditions. Based on pathogen quantification using stem colonization derived from traditional plating assays and QPCR, the resistance level of several cultivars is more clearly defined and discussed. Resumen Los cambios en la producción de papa en los pasados 10 a 20 años, han resultado en un aumento en el énfasis ubicado en el mejoramiento para la resistencia al marchitamiento por Verticillium, causado por Verticillium dahliae Kleb. Mientras que muchos cultivares de piel tipo russet se han liberado recientemente con resistencia reportada al marchitamiento por Verticillium, la información carece del nivel de colonización del patógeno, y de aquí que no se conozca el nivel de resistencia genética verdadera. Se sembraron ocho cultivares con piel tipo russet en ensayos de campo con niveles bajo y alto de V. dahliae en el suelo, y evaluados para marchitez, colonización del tallo, rendimiento, y decoloración vascular del tubérculo. Se evaluó recientemente un ensayo QPCR, con relaciones fuertes a ensayos de cultivos en placas sobre tres fechas de muestreo del tallo. Adicionalmente, los niveles de colonización del tallo, como se determinaron por QPCR, se relacionaron al marchitamiento y a la decoloración vascular del tubérculo. No obstante, el rendimiento total no exhibió una relación fuerte a ningún otro parámetro evaluado en este estudio. Los resultados de estos estudios indican que están presentes diversos niveles de resistencia verdadera en las variedades de piel tipo russet evaluadas, y que el ensayo de QPCR puede ser confiable en la evaluación rápida de resistencia a V. dahliae bajo condiciones de campo. Con base en la cuantificación del patógeno mediante el uso de la colonización del tallo derivada de los ensayos tradicionales de placas y QPCR, el nivel de resistencia de varios cultivares está más claramente definido y discutido

Background Field Equations for the Duality Symmetric String

This paper describes the background field equations for strings in T-duality symmetric formalisms in which the dimension of target space is doubled and the sigma model supplemented with constraints. These are calculated by demanding the vanishing of the beta-functional of the sigma model couplings in the doubled target space. We demonstrate the equivalence with the background field equations of the standard string sigma model.Comment: 26 pages, latex, v2 typos correcte

Promoting well-being: Crisis, loss and alcohol

Well-being is a concept which can connect together a number of important ideas that have a strong resonance for professional education and practice across the human services. This can critically include considerations of illness, crisis, and loss. Such acute moments in individuals’ lives can be examined through their precipitating events, coping mechanisms, and responses. This article explores some of the dimensions of well-being and how they facilitate a greater understanding of illness, crisis, and loss. These deliberations are then exemplified through a focus on alcohol and other drug use

Distribution and relative abundance of caribou in the Hudson Plains Ecozone of Ontario

To determine past distribution and relative abundance of caribou (Rangifer tarandus caribou) in the Hudson Plains Ecozone (HPE) of Ontario, we reviewed past HPE-wide winter systematic aerial surveys, partial winter systematic surveys, summer photographic surveys, incidental observations of caribou, and other sources of information from the period 1950—2003. We conducted new HPE-wide aerial surveys in February 2003 and 2004 to evaluate current distribution patterns. From this information, we defined 9 core wintering areas in the HPE and differentiated between 3 catego¬ries of relative abundance. Wintering areas for the January—March period have changed relatively little over the past 45 years. Summer distribution of caribou along the Hudson Bay coast apparently shifted or expanded from the area west of the Severn River to the central and eastern portions of the coast since the 1980s, and caribou observations have become much more common in the area east of the Winisk River since 1998. Because major resource development activities in the HPE are proposed and some are imminent, we recommend additional caribou surveys to document current caribou population identity, size, and distribution, and research projects to better define caribou wintering areas, calving areas, and movement patterns in the HPE