322 research outputs found

    A Study of the Colorado Commission on Judicial Qualifications

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    Dynamical Characterization of Galaxies at z~4-6 via Tilted Ring Fitting to ALMA [CII] Observations

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    Until recently, determining the rotational properties of galaxies in the early universe (z>4, Universe age <1.5Gyr) was impractical, with the exception of a few strongly lensed systems. Combining the high resolution and sensitivity of ALMA at (sub-) millimeter wavelengths with the typically high strength of the [CII] 158um emission line from galaxies and long-developed dynamical modeling tools raises the possibility of characterizing the gas dynamics in both extreme starburst galaxies and normal star forming disk galaxies at z~4-7. Using a procedure centered around GIPSY's ROTCUR task, we have fit tilted ring models to some of the best available ALMA [CII] data of a small set of galaxies: the MS galaxies HZ9 & HZ10, the Damped Lyman-alpha Absorber (DLA) host galaxy ALMA J0817+1351, the submm galaxies AzTEC/C159 and COSMOS J1000+0234, and the quasar host galaxy ULAS J1319+0950. This procedure directly derives rotation curves and dynamical masses as functions of radius for each object. In one case, we present evidence for a dark matter halo of O(10^11) solar masses. We present an analysis of the possible velocity dispersions of AzTEC/C159 and ULAS J1319+0950 based on matching simulated observations to the integrated [CII] line profiles. Finally, we test the effects of observation resolution and sensitivity on our results. While the conclusions remain limited at the resolution and signal-to-noise ratios of these observations, the results demonstrate the viability of the modeling tools at high redshift, and the exciting potential for detailed dynamical analysis of the earliest galaxies, as ALMA achieves full observational capabilities.Comment: 20 pages, 6 figures, Accepted for publication in Ap

    Rates, risk factors & methods of self harm among minority ethnic groups in the UK: a systematic review

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    <p>Abstract</p> <p>Background</p> <p>Studies suggest that the rates of self harm vary by ethnic group, but the evidence for variation in risk factors has not been synthesised to inform preventive initiatives.</p> <p>Methods</p> <p>We undertook a systematic literature review of research about self harm that compared at least two ethnic groups in the United Kingdom.</p> <p>Results</p> <p>25 publications from 1765 titles and abstracts met our inclusion criteria. There was higher rate of self harm among South Asian women, compared with South Asian men and White women. In a pooled estimate from two studies, compared to their white counterparts, Asian women were more likely to self harm (Relative Risk 1.4, 95%CI: 1.1 to 1.8, p = 0.005), and Asian men were less likely to self harm (RR 0.5, 95% CI: 0.4 to 0.7, p < 0.001). Some studies concluded that South Asian adults self-harm impulsively in response to life events rather than in association with a psychiatric illness. Studies of adolescents showed similar methods of self harm and interpersonal disputes with parents and friends across ethnic groups. There were few studies of people of Caribbean, African and other minority ethnic groups, few studies took a population based and prospective design and few investigated self harm among prisoners, asylum seekers and refugees.</p> <p>Conclusion</p> <p>This review finds some ethnic differences in the nature and presentation of self harm. This argues for ethnic specific preventive actions. However, the literature does not comprehensively cover the UK's diverse ethnic groups.</p

    Searching for C ii Emission from the First Sample of z ∼ 6 O i Absorption-associated Galaxies with the Atacama Large Millimeter/submillimeter Array

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    We report the first statistical analyses of [C ii ] and dust continuum observations in six strong O i absorber fields at the end of the reionization epoch obtained by the Atacama Large Millimeter/submillimeter Array (ALMA). Combined with one [C ii ] emitter reported in Wu et al., we detect one O i -associated [C ii ] emitter in six fields. At redshifts of O i absorbers in nondetection fields, no emitters are brighter than our detection limit within impact parameters of 50 kpc and velocity offsets between ±200 km s ^−1 . The averaged [C ii ]-detection upper limit is 50 kpc) and having larger outflow velocities within ±600 km s ^−1 . If these detections are confirmed in the future, then the mechanism of pushing metals at larger distances with higher velocities needs to be further explored from the theoretical side

    Borrelia recurrentis employs a novel multifunctional surface protein with anti-complement, anti-opsonic and invasive potential to escape innate immunity

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    Borrelia recurrentis, the etiologic agent of louse-borne relapsing fever in humans, has evolved strategies, including antigenic variation, to evade immune defence, thereby causing severe diseases with high mortality rates. Here we identify for the first time a multifunctional surface lipoprotein of B. recurrentis, termed HcpA, and demonstrate that it binds human complement regulators, Factor H, CFHR-1, and simultaneously, the host protease plasminogen. Cell surface bound factor H was found to retain its activity and to confer resistance to complement attack. Moreover, ectopic expression of HcpA in a B. burgdorferi B313 strain, deficient in Factor H binding proteins, protected the transformed spirochetes from complement-mediated killing. Furthermore, HcpA-bound plasminogen/plasmin endows B. recurrentis with the potential to resist opsonization and to degrade extracellular matrix components. Together, the present study underscores the high virulence potential of B. recurrentis. The elucidation of the molecular basis underlying the versatile strategies of B. recurrentis to escape innate immunity and to persist in human tissues, including the brain, may help to understand the pathological processes underlying louse-borne relapsing fever

    Reverberation Mapping of the Kepler-Field AGN KA1858+4850

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    KA1858+4850 is a narrow-line Seyfert 1 galaxy at redshift 0.078 and is among the brightest active galaxies monitored by the Kepler mission. We have carried out a reverberation mapping campaign designed to measure the broad-line region size and estimate the mass of the black hole in this galaxy. We obtained 74 epochs of spectroscopic data using the Kast Spectrograph at the Lick 3-m telescope from February to November of 2012, and obtained complementary V-band images from five other ground-based telescopes. We measured the H-beta light curve lag with respect to the V-band continuum light curve using both cross-correlation techniques (CCF) and continuum light curve variability modeling with the JAVELIN method, and found rest-frame lags of lag_CCF = 13.53 (+2.03, -2.32) days and lag_JAVELIN = 13.15 (+1.08, -1.00) days. The H-beta root-mean-square line profile has a width of sigma_line = 770 +/- 49 km/s. Combining these two results and assuming a virial scale factor of f = 5.13, we obtained a virial estimate of M_BH = 8.06 (+1.59, -1.72) x 10^6 M_sun for the mass of the central black hole and an Eddington ratio of L/L_Edd ~ 0.2. We also obtained consistent but slightly shorter emission-line lags with respect to the Kepler light curve. Thanks to the Kepler mission, the light curve of KA1858+4850 has among the highest cadences and signal-to-noise ratios ever measured for an active galactic nucleus; thus, our black hole mass measurement will serve as a reference point for relations between black hole mass and continuum variability characteristics in active galactic nuclei
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