3,307 research outputs found
Gravitino fields in Schwarzschild black hole spacetimes
The analysis of gravitino fields in curved spacetimes is usually carried out
using the Newman-Penrose formalism. In this paper we consider a more direct
approach with eigenspinor-vectors on spheres, to separate out the angular parts
of the fields in a Schwarzschild background. The radial equations of the
corresponding gauge invariant variable obtained are shown to be the same as in
the Newman-Penrose formalism. These equations are then applied to the
evaluation of the quasinormal mode frequencies, as well as the absorption
probabilities of the gravitino field scattering in this background.Comment: 21 pages, 2 figures. arXiv admin note: text overlap with
arXiv:1006.3327 by other author
Microstability analysis of pellet fuelled discharges in MAST
Reactor grade plasmas are likely to be fuelled by pellet injection. This
technique transiently perturbs the profiles, driving the density profile hollow
and flattening the edge temperature profile. After the pellet perturbation, the
density and temperature profiles relax towards their quasi-steady-state shape.
Microinstabilities influence plasma confinement and will play a role in
determining the evolution of the profiles in pellet fuelled plasmas. In this
paper we present the microstability analysis of pellet fuelled H-mode MAST
plasmas. Taking advantage of the unique capabilities of the MAST Thomson
scattering system and the possibility of synchronizing the eight lasers with
the pellet injection, we were able to measure the evolution of the post-pellet
electron density and temperature profiles with high temporal and spatial
resolution. These profiles, together with ion temperature profiles measured
using a charge exchange diagnostic, were used to produce equilibria suitable
for microstability analysis of the equilibrium changes induced by pellet
injection. This analysis, carried out using the local gyrokinetic code GS2,
reveals that the microstability properties are extremely sensitive to the rapid
and large transient excursions of the density and temperature profiles, which
also change collisionality and beta e significantly in the region most strongly
affected by the pellet ablation.Comment: 21 pages, 10 figures. This is an author-created, un-copyedited
version of an article submitted for publication in Plasma Physics and
Controlled Fusion. IOP Publishing Ltd is not responsible for any errors or
omissions in this version of the manuscript or any version derived from i
Therapy-based exercise from the perspective of adult patients: a qualitative systematic review conducted using an ethnographic approach
© The Author(s) 2019.Objectives: Many patients do not meet recommended levels of therapy-based exercise. This review aims to explore how adult patients view being prescribed therapy-based exercise, the information/education they are given and receive and if/how they independently practise and adhere. Design: A qualitative systematic review conducted using an ethnographic approach and in accordance with the PRISMA statement. Sources: PubMed, CINAHL, SCOPUS and EMBASE databases (01 January 2000–31 December 2018). Methods: Qualitative studies with a focus on engagement/adherence with therapy-based exercise were included. Data extraction and quality appraisal were undertaken by two reviewers. Results were discussed and data synthesized. Results: A total of 20,294 titles were screened, with data extracted from 39 full texts and data from 18 papers used to construct three themes. ‘The Guidance received’ suggests that the type of delivery desired to support and sustain engagement was context-dependent and individually situated. ‘The Therapist as teacher’ advocates that patients see independent therapy-based exercise as a shared activity and value caring, kind and professional qualities in their therapist. ‘The Person as learner’ proposes that when having to engage with and practise therapy-based exercise because of ill-health, patients often see themselves as new learners who experience fear and uncertainty about what to do. Patients may have unacknowledged ambivalences about learning that impact on engagement and persistence. Conclusion: The quality of the interaction between therapists and patients appears integral to patients engaging with, and sustaining practice of, rehabilitation programmes. Programmes need to be individualized, and health care professionals need to take patients’ previous experiences and ambivalences in motivation and empowerment into account.Peer reviewe
Photoevaporation and close encounters: how the environment around Cygnus OB2 affects the evolution of protoplanetary disks
In our Galaxy, star formation occurs in a variety of environments, with a
large fraction of stars formed in clusters hosting massive stars. OB stars have
an important feedback on the evolution of protoplanetary disks around nearby
young stars and likely on the process of planet formation occurring in them.
The nearby massive association Cygnus OB2 is an outstanding laboratory to study
this feedback. It is the closest massive association to our Sun, and hosts
hundreds of massive stars and thousands of low mass members. In this paper, we
analyze the spatial variation of the disk fraction in Cygnus OB2 and we study
its correlation with the local values of Far and Extreme ultraviolet radiation
fields and the local stellar surface density. We present definitive evidence
that disks are more rapidly dissipated in the regions of the association
characterized by intense local UV field and large stellar density. In
particular, the FUV radiation dominates disks dissipation timescales in the
proximity (i.e. within 0.5 pc) of the O stars. In the rest of the association,
EUV photons potentially induce a significant mass loss from the irradiated
disks across the entire association, but the efficiency of this process is
reduced at increasing distances from the massive stars due to absorption by the
intervening intracluster material. We find that disk dissipation due to close
stellar encounters is negligible in Cygnus OB2, and likely to have affected 1%
or fewer of the stellar population. Disk dissipation is instead dominated by
photoevaporation. We also compare our results to what has been found in other
young clusters with different massive populations, concluding that massive
associations like Cygnus OB2 are potentially hostile to protoplanetary disks,
but that the environments where disks can safely evolve in planetary systems
are likely quite common in our Galaxy.Comment: Accepted for publication in ApJS as part of the special issue on the
Chandra Cygnus OB2 Legacy Projec
Naturally processed measles virus peptide eluted from class II HLA-DRB1*03 recognized by T lymphocytes from human blood
AbstractThis is the first report of the direct identification of a HLA-DRB1*03 measles-derived peptide from measles virus infected EBV-transformed B cells. We purified HLA-DR3-peptide complexes from EBV-B cells infected with measles virus (Edmonston strain) and sequenced the HLA-DR3-peptides by mass spectrometry. A class II peptide, derived from a measles phosphoprotein, ASDVETAEGGEIHELLRLQ (P1, residues 179–197), exhibited the capacity to stimulate peripheral blood mononuclear cells to proliferate. Our data provides direct evidence that the antigenic peptide of measles virus was processed by antigen-presenting cells, presented in the context of HLA class II molecules, and was recognized by peripheral blood T cells from healthy individuals previously immunized with measles vaccine. The approach described herein provides a useful methodology for the future identification of HLA-presented pathogen-derived epitopes using mass spectrometry. The study of cell-mediated immune responses to the measles-derived peptide in immune persons should provide significant insight into the design and development of new vaccines
Calibration of <i>Herschel</i> SPIRE FTS observations at different spectral resolutions
The SPIRE Fourier Transform Spectrometer on-board the Herschel Space Observatory had two standard spectral resolution modes for science observations: high resolution (HR) and low resolution (LR), which could also be performed in sequence (H+LR). A comparison of the HR and LR resolution spectra taken in this sequential mode revealed a systematic discrepancy in the continuum level. Analysing the data at different stages during standard pipeline processing demonstrates that the telescope and instrument emission affect HR and H+LR observations in a systematically different way. The origin of this difference is found to lie in the variation of both the telescope and instrument response functions, while it is triggered by fast variation of the instrument temperatures. As it is not possible to trace the evolution of the response functions using housekeeping data from the instrument subsystems, the calibration cannot be corrected analytically. Therefore, an empirical correction for LR spectra has been developed, which removes the systematic noise introduced by the variation of the response functions
Correcting the extended-source calibration for the <i>Herschel</i>-SPIRE Fourier-transform spectrometer
We describe an update to the Herschel-Spectral and Photometric Imaging Receiver (SPIRE) Fourier-transform spectrometer (FTS) calibration for extended sources, which incorporates a correction for the frequency-dependent far-field feedhorn efficiency, ηff. This significant correction affects all FTS extended-source calibrated spectra in sparse or mapping mode, regardless of the spectral resolution. Line fluxes and continuum levels are underestimated by factors of 1.3–2 in thespectrometer long wavelength band (447–1018 GHz; 671–294 μm) and 1.4–1.5 in the spectrometer short wavelength band (944–1568 GHz; 318–191 μm). The correction was implemented in the FTS pipeline version 14.1 and has also been described in the SPIRE Handbook since 2017 February. Studies based on extended-source calibrated spectra produced prior to this pipeline version should be critically reconsidered using the current products available in the Herschel Science Archive. Once the extended-source calibrated spectra are corrected for ηff, the synthetic photometry and the broad-band intensities from SPIRE photometer maps agree within 2–4 per cent – similar levels to the comparison of point-source calibrated spectra and photometry from point-source calibrated maps. The two calibration schemes for the FTS are now self-consistent: the conversion between the corrected extended-source and point-source calibrated spectra can be achieved with the beam solid angle and a gain correction that accounts for the diffraction loss
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