499 research outputs found
Observations on the crab fishery of Mangalore coast
Considerable quantities of crabs are caught in the inshore waters of
Mangalore coast and from the river mouths of this zone during DecemberJune
period and these find a ready market in the towns. Crabs are brought
to Mangalore town from the Ullal estuary and from Kasa,rgod, Kumbla,
Bengre and Mulki centres. The fishery is more active during FebruaryApril
when fishing for the shoaling fishes reaches the waning period. Unlike
in other towns in .the south or in the north, crab meat is very much in demand
in Mangalore
Ancient Leishmania coronin (CRN12) is involved in microtubule remodeling during cytokinesis
In general, coronins play an important role in actin-based processes, and are expressed in a variety of eukaryotic cells, including Leishmania. Here, we show that Leishmania coronin preferentially distributes to the distal tip during cytokinesis, and interacts with microtubules through a microtubule-based motor, kinesin K39. We further show that reduction in coronin levels by 40-50% in heterozygous coronin mutants results in generation of bipolar cells (25-30%), specifically in the log phase, owing to unregulated growth of the corset microtubules. Further analysis of bipolar cells revealed that the main cause of generation of bipolar cell morphology is the intrusion of the persistently growing corset microtubules into the other daughter cell corset from the opposite direction. This defect in cytokinesis, however, disappears upon episomal gene complementation. Additionally, our attempts to prepare homozygous mutants were unsuccessful, as only the aneuploid cells survive the selection process. These results indicate that coronin regulates microtubule remodeling during Leishmania cytokinesis and is essentially required for survival of these parasites in culture
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The utility of a correct choice under conditions of verbal reinforcement
The purpose of this study was to test Siegel's utility model of
choice behavior under conditions of verbal reinforcement, in a nursery
school population of both sexes. Two major hypotheses were
tested: The ordinal hypothesis stated that under conditions of increased
value of the payoff subjects' stable-state strategies will
occur in increasing order from matching to pure strategies. The
quantitative hypothesis stated that there is no difference between the
predicted and observed stable-state strategies.
In order to test the above mentioned hypotheses, thirty subjects
were randomly chosen from a preschool population. These in turn,
were assigned to the three payoff conditions; no payoff, payoff,
payoff-loss. Each subject was observed under two different experiments
which were identical with respect to all utility relevant features,
but were different with respect to the proportion of the occurrence of the two events, π[subscript i] values. In one experiment π₁ was
set equal to .75 and in the other π₁ was set equal to .80. The apparatus
used was Humphrey's (1939) modified, two-light situation.
This apparatus had never been used before with a preschool population.
The occurrence of the two lights was predetermined randomly
and was held constant during the experiment. The order in which
the two experiments were presented to each of the subjects was
random so that not all subjects received the same π[subscript i]. Reinforcement
was given by the same individual in both the experiments. The
most frequently occurring event was reversed for each of the subjects
from the first to the second testing situation. Under the no
payoff condition the subjects did not receive any extrinsic reinforcement.
Under the payoff condition the subjects received positive
reinforcement only for the correct choice. Under the payoff-loss
condition the subjects were reinforced positively for the correct
choice and reinforced negatively for the incorrect choice. The positive
verbal reinforcement used was, 'That's right, that's very good.'
The negative verbal reinforcement used was, 'That's wrong, that's
not very good.' The data under both the experiments were in the
form of p[superscript -] values, the proportion in which the subject chose the most
frequently occurring event.
Before testing for the overall ordinal hypothesis the data were
tested for sex differences. It was found that there was a significant difference between the stable-state strategies of boys and girls under
the no payoff condition when π₁ = .80 and under the payoff condition
when π₁ = .75.
The ordinal hypothesis which predicted increase in stable-state
strategy with increased payoff was considered untenable as a result
of inspecting the data, the data were such as to suggest that the type
of verbal reinforcement used, namely, a repetitive, simple, monotonous
type, was an ineffective reinforcer. The data were further
examined to see if these subjects had at least a rudimentary grasp of the
concept of probability adequate to the task in the experiment. It
was concluded that the sample of preschool children exhibited little,
if any, understanding of the concept of probability.
In testing the second hypothesis, the Siegel model was used to
quantitatively predict the stable-state strategies of boys and girls
from one experiment to the observed stable-state strategies in the
other experiment. Similarly, the data from the second experiment
was used to predict the stable-state strategies of boys and girls in
the first experiment. It was concluded that the strategies predicted
from the model for both boys or girls under the no payoff and payoff-loss condition did not differ significantly from their observed stable-state strategies. Under the payoff condition, the model predicted
accurately for boys but not for girls.
Heretofore, the Siegel model has been used to predict only with group data. But, since utility refers to subjective value, in this
study the model was used to predict the stable-state strategies of
individual boys and girls, from one condition to the other. It was
concluded that in predicting the individual stable-state strategies the
Siegel model does not predict for girls under conditions of the present
study
Heat Transfer in Horizontal Copper Tube Heated by Electric Heating Process
Heat transfer from electrical and electronics component is essential for better performance of that electrical system, The maximum heat transfer from that system results long period durability. In most of the system base provided for equipments are very small and placed in a very complicated position. so heat transfer by forced convection is not easy for that purpose.The heat transfer by natural convection is the familiar technique used in electronics cooling; there is huge group of apparatus that lends itself to natural convection .This category consist of stand-alone correspondence such as modems and small computers having an array of printed circuit boards (PCB) accumulate within an area. Natural convection heat transfer in heated horizontal duct drive away heat from the interior surface is offered. The duct is open-ended and round in cross section. The test section is heated by provision of heating coils, where constant wall heat flux mentioned. Heat transfer experiment is carried out for channel of 50 mm. internal diameter and 4 mm thickness with length 600 mm. Ratios of length to diameter of the channel are taken as L/D = 12. Wall heat fluxes maintained at q// = 300 W/m2 to 3150 W/m2 . A methodical investigational record for the localsteady state natural convection heat transfer activities is obtained. The wall heating condition on local steady-state heat transfer phenomena are studied.The present experimental data is compared with the existing theoretical and experimental results for the cases of vertical smooth tubes.
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McrD binds asymmetrically to methyl-coenzyme M reductase improving active-site accessibility during assembly
Methyl-coenzyme M reductase (MCR) catalyzes the formation of methane, and its activity accounts for nearly all biologically produced methane released into the atmosphere. The assembly of MCR is an intricate process involving the installation of a complex set of posttranslational modifications and the unique Ni-containing tetrapyrrole called coenzyme F430. Despite decades of research, details of MCR assembly remain largely unresolved. Here, we report the structural characterization of MCR in two intermediate states of assembly. These intermediate states lack one or both F430 cofactors and form complexes with the previously uncharacterized McrD protein. McrD is found to bind asymmetrically to MCR, displacing large regions of the alpha subunit and increasing active-site accessibility for the installation of F430-shedding light on the assembly of MCR and the role of McrD therein. This work offers crucial information for the expression of MCR in a heterologous host and provides targets for the design of MCR inhibitors
Ectopic pregnancy in a tertiary care center: a retrospective study
Background: Ectopic pregnancy is an obstetric emergency which if not diagnosed in time can cost the life of the patient. This emphasizes the importance of diagnosing this perilous condition and hence this study was undertaken to study symptoms with which the patients with ectopic pregnancy present.Methods: Retrospective study of 5 years was done in the department of Obstetrics and Gynecology, M. S. Ramaiah medical college and teaching hospital, Bangalore, India between January 2011 to January 2016. Detailed analysis of patients with ectopic pregnancy inclusive of the age and clinical features were studied.Results: A total of 90 patients with ectopic pregnancy were studied. 95.5% of the patients (n=86) presented with abdominal pain, 81.1% (n=73) of the patients presented with amenorrhea, 24.4% (n=22) patients presented with bleeding per vagina, 30% (n=27) patients with nausea, vomiting and 48.8% (n=44) presented with fainting and giddiness.Conclusions: It is very essential to study the symptoms of ectopic pregnancy as this may help in early detection of ectopic pregnancy and hence can reduce the mortality in this catastrophic condition
Preparation of Silver Decorated Reduced Graphene Oxide Nanohybrid for Effective Photocatalytic Degradation of Indigo Carmine Dye
Background: Even though silver decorated reduced graphene oxide (Ag-rGO) shows max-
imum absorptivity in the UV region, most of the research on the degradation of dyes using Ag-rGO is
in the visible region. Therefore the present work focused on the photocatalytic degradation of indigo
carmine (IC) dye in the presence of Ag-rGO as a catalyst by UV light irradiation.
Methods: In this context, silver-decorated reduced graphene oxide hybrid material was fabricated and
explored its potential for the photocatalytic degradation of aqueous IC solution in the UV region. The
decoration of Ag nanoparticles on the surface of the rGO nanosheets is evidenced by TEM analysis.
The extent of mineralization of the dye was measured by estimating chemical oxygen demand (COD)
values before and after irradiation.
Results: The synthesized Ag-rGO binary composites displayed excellent photocatalytic activity in 2
Χ 10-5 M IC concentration and 5mg catalyst loading. The optical absorption spectrum of Ag-rGO
showed that the energy band-gap was found to be 2.27 eV, which is significantly smaller compared to
the band-gap of GO. 5 mg of Ag-rGO was found to be an optimum quantity for the effective degrada-
tion of IC dye. The degradation rate increases with the decrease in the concentration of the dye at al-
kaline pH conditions. The photocatalytic efficiency was 92% for the second time.
Conclusion: The impact of the enhanced reactive species generation was consistent with higher pho-
tocatalytic dye degradation. The photocatalytic mechanism has been proposed and the hydroxyl radi-
cal was found to be the reactive species responsible for the degradation of dye. The feasibility of reus-
ing the photocatalyst showed that the photocatalytic efficiency was very effective for the second tim
Pressure controlled trimerization for switching of anomalous Hall effect in triangular antiferromagnet MnSn
Here, we present a detailed theoretical and experimental study on the
pressure induced switching of anomalous Hall effect (AHE) in the triangular
antiferromagnetic (AFM) compound MnSn. Our theoretical model suggests
pressure driven significant splitting of the in-plane Mn bond lengths an
effective trimerization, which in turn stabilizes a helical AFM ground state by
modifying the inter-plane exchange parameters in the system. We experimentally
demonstrate that the AHE in MnSn reduces from 5 cm at ambient
pressure to zero at an applied pressure of about 1.5 GPa. Furthermore, our
pressure dependent magnetization study reveals that the conventional triangular
AFM ground state of MnSn systematically transforms into the helical AFM
phase where the symmetry does not support a non-vanishing Berry curvature
required for the realization of a finite AHE. The pressure dependent x-ray
diffraction (XRD) study rules out any role of structural phase transition in
the observed phenomenon. In addition, the temperature dependent in-plane
lattice parameter at ambient pressure is found to deviate from the monotonic
behavior when the system enters into the helical AFM phase, thereby, supporting
the proposed impact of trimerization in controlling the AHE. We believe that
the present study makes an important contribution towards understanding the
stabilization mechanism of different magnetic ground states in MnSn and
related materials for their potential applications pertaining to AHE switching
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